Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Luoyan, Ai"'
Autor:
Xiaojing Xu, Luoyan Ai, Keshu Hu, Li Liang, Minzhi Lv, Yan Wang, Yuehong Cui, Wei Li, Qian Li, Shan Yu, Yi Feng, Qing Liu, Ying Yang, Jiao Zhang, Fei Xu, Yiyi Yu, Tianshu Liu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Immunotherapy confers little to no benefit in the treatment of microsatellite stable (MSS) metastatic colorectal cancer (mCRC). Mechanistic insights suggested that epidermal growth factor receptor (EGFR) antibody plus irinotecan might augmen
Externí odkaz:
https://doaj.org/article/c52ef4cf4de347268916103efecfb9a4
Autor:
Giwa, Abdulmoseen Segun, Maurice, Ndungutse Jean, Luoyan, Ai, Liu, Xinxin, Yunlong, Yang, Hong, Zhao
Publikováno v:
In Heliyon September 2023 9(9)
Autor:
Mengling Liu, Xiaojing Xu, Ke Peng, Pengcong Hou, Yitao Yuan, Suyao Li, Xun Sun, Zhongyi Shi, Jiayu Zhang, Yu Dong, Qing Liu, Luoyan Ai, Li Liang, Lu Gan, Qihong Huang, Yiyi Yu, Tianshu Liu
Publikováno v:
Oncogenesis, Vol 11, Iss 1, Pp 1-11 (2022)
Abstract BRAF V600E-mutant colorectal cancer (CRC) is a rare subtype of colorectal cancer with poor prognosis. Compelling evidence indicates that the heparanase (HPSE) gene has multiple functions in cancer, however, its role in BRAF V600E-mutant CRC
Externí odkaz:
https://doaj.org/article/2ed35b4959e841c7b11e32e0a43d51aa
Autor:
Yimeng Ren, Yun Qian, Luoyan Ai, Yile Xie, Yaqi Gao, Ziyan Zhuang, Jinxian Chen, Ying-Xuan Chen, Jing-Yuan Fang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Transport protein particle (TRAPP) is a multimeric protein complex regulating membrane trafficking pathways. Here the authors show that TRAPPC4, a core subunit of TRAPP complex, is required for RAB11-mediated recycling of PD-L1, affecting T-cell-medi
Externí odkaz:
https://doaj.org/article/42b747d961694a008ae75ed740330fe4
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
PurposeWe aimed to investigate the mortality patterns and quantitatively assess the risks of cardiovascular death (CVD) in patients with colorectal cancer (CRC). We also established a competing-risk model to predict the probability of CVD for patient
Externí odkaz:
https://doaj.org/article/1b7cdf03da3f4f81a24d930c32cd1c28
Autor:
Qian Li, Yimei Wang, Qing Liu, Jie Gao, Tianshu Liu, Duojiao Wu, Luoyan Ai, Yuan Ji, Shihai Zhao, Yue-Hong Cui, Xiaoshi Jin, Jingjie Li, Yiyi Yu
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 10 (2021)
Externí odkaz:
https://doaj.org/article/3d37d71db6874d35ac690debb0759c5f
Publikováno v:
PLoS ONE, Vol 16, Iss 9, p e0257415 (2021)
Degradation of 2,4,6-trichlorophenol (2,4,6-TCP) by zero-valent iron (ZVI) activating three common peroxides (peroxymonosulfate (PMS), hydrogen peroxide (H2O2), and peroxydisulfate (PS)) was investigated. The effects of ZVI dosage, peroxides concentr
Externí odkaz:
https://doaj.org/article/6e7205af30f64b5db51121f110f5021c
Autor:
Wei Wu, Lin Jinyi, Yan Wang, Yiyi Yu, Hang Jin, Qian Li, Luoyan Ai, Mengling Liu, Shan Yu, Suyao Li, Qing Liu, Tianshu Liu
Publikováno v:
European Journal of Cancer. 157:10-20
Combination of immune checkpoint inhibitor (ICI) and anti-vascular endothelial growth factor (VEGF) therapy has increasingly become a promising strategy in various tumors. However, the combination might be associated with increased cardiotoxicities.
In the last decade, the use of immune checkpoint inhibitors (ICIs) targeting cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) and programmed cell death protein 1 (PD-1) and its ligand (PD-L1) has significantly improved prognosis of patients with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92e2b6d32f971e0bc6a89a979697d404
https://doi.org/10.21203/rs.3.rs-2364882/v1
https://doi.org/10.21203/rs.3.rs-2364882/v1
Publikováno v:
Gut. 70:2261-2272
ObjectiveAs a canonical membrane tethering factor, the function of synbindin has been expanding and indicated in immune response. Here, we investigated the role of synbindin in the regulation of toll-like receptor 4 (TLR4) signalling and macrophage r