Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Luoling Xu"'
Autor:
Alberto J Leon, Viktoriya Borisevich, Nahal Boroumand, Robert Seymour, Rebecca Nusbaum, Olivier Escaffre, Luoling Xu, David J Kelvin, Barry Rockx
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 12, Iss 3, p e0006343 (2018)
Henipavirus infection causes severe respiratory and neurological disease in humans that can be fatal. To characterize the pathogenic mechanisms of henipavirus infection in vivo, we performed experimental infections in ferrets followed by genome-wide
Externí odkaz:
https://doaj.org/article/68c6f98461c44ecc96c48a268fbcd8cb
Autor:
Stéphane G Paquette, David Banner, Stephen S H Huang, Raquel Almansa, Alberto Leon, Luoling Xu, Jessica Bartoszko, David J Kelvin, Alyson A Kelvin
Publikováno v:
PLoS Pathogens, Vol 11, Iss 10, p e1005173 (2015)
Seasonal influenza viruses are typically restricted to the human upper respiratory tract whereas influenza viruses with greater pathogenic potential often also target extra-pulmonary organs. Infants, pregnant women, and breastfeeding mothers are high
Externí odkaz:
https://doaj.org/article/d18717a363a84475a29f9db2719183b0
Autor:
Mark J Cameron, Alyson A Kelvin, Alberto J Leon, Cheryl M Cameron, Longsi Ran, Luoling Xu, Yong-Kyu Chu, Ali Danesh, Yuan Fang, Qianjun Li, Austin Anderson, Ronald C Couch, Stephane G Paquette, Ndingsa G Fomukong, Otfried Kistner, Manfred Lauchart, Thomas Rowe, Kevin S Harrod, Colleen B Jonsson, David J Kelvin
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e45842 (2012)
In terms of its highly pathogenic nature, there remains a significant need to further define the immune pathology of SARS-coronavirus (SARS-CoV) infection, as well as identify correlates of immunity to help develop vaccines for severe coronaviral inf
Externí odkaz:
https://doaj.org/article/83e201f30e734dff9f9277efcd9a9996
Autor:
Alyson A Kelvin, David Banner, Giuliano Silvi, Maria Luisa Moro, Nadir Spataro, Paolo Gaibani, Francesca Cavrini, Anna Pierro, Giada Rossini, Mark J Cameron, Jesus F Bermejo-Martin, Stéphane G Paquette, Luoling Xu, Ali Danesh, Amber Farooqui, Ilaria Borghetto, David J Kelvin, Vittorio Sambri, Salvatore Rubino
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 5, Iss 8, p e1279 (2011)
The Chikungunya virus infection zones have now quickly spread from Africa to parts of Asia, North America and Europe. Originally thought to trigger a disease of only mild symptoms, recently Chikungunya virus caused large-scale fatalities and widespre
Externí odkaz:
https://doaj.org/article/534b3931cd724bb496bccd0c79e5ef73
Autor:
David J. Kelvin, Stephen S. H. Huang, Alberto J. Leόn, Stéphane G. Paquette, Alyson A. Kelvin, David Banner, Luoling Xu
Publikováno v:
Virology. :177-183
The major burden of influenza morbidity resides within the elderly population. The challenge managing influenza-associated illness in the elderly is the decline of immune function, where mechanisms leading to immunological senescence have not been el
Autor:
Robert L. Seymour, Olivier Escaffre, Nahal Boroumand, Luoling Xu, Viktoriya Borisevich, Barry Rockx, Alberto J. Leon, David J. Kelvin, Rebecca J. Nusbaum
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 12, Iss 3, p e0006343 (2018)
PLoS Neglected Tropical Diseases (print), 12(3):e0006343. Public Library of Science
PLoS Neglected Tropical Diseases
PLOS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases (print), 12(3):e0006343. Public Library of Science
PLoS Neglected Tropical Diseases
PLOS Neglected Tropical Diseases
Henipavirus infection causes severe respiratory and neurological disease in humans that can be fatal. To characterize the pathogenic mechanisms of henipavirus infection in vivo, we performed experimental infections in ferrets followed by genome-wide
Autor:
Pak-Kei M. Chan, Jesus F. Bermejo-Martin, David J. Kelvin, Julio C. Medina, Yuan Fang, Patricia V. Turner, Longsi Ran, Mark J. Cameron, Tassie L. Collins, Luoling Xu, Nutan Mytle, Ali Danesh, Cheryl M. Cameron, Ran Ran, Thomas Rowe, Timothy J. Sullivan, Michael G. Johnson
Publikováno v:
Journal of Virology
How viral and host factors contribute to the severe pathogenicity of the H5N1 subtype of avian influenza virus infection in humans is poorly understood. We identified three clusters of differentially expressed innate immune response genes in lungs fr
Autor:
Steven E. Bosinger, Charit Seneviratne, Luoling Xu, Marcus Czub, Thomas Rowe, David Banner, Alyson A. Kelvin, David J. Kelvin, Mark E. DeVries, Ali Danesh, Colleen B. Jonsson, Longsi Ran, Cheryl M. Cameron, Mark J. Cameron
Publikováno v:
Molecular Immunology
Chemokines and their receptors function in the recruitment and activation of cells of the immune system to sites of inflammation. As such, chemokines play an important role in mediating pathophysiological events during microbial infection. In particu
Autor:
David J. Kelvin, Charit Seneviratne, Atsuo Ochi, Ali Danesh, Markus Czub, Mark J. Cameron, Steven E. Bosinger, David Banner, Longsi Ran, Cheryl M. Cameron, Luoling Xu, Thomas Rowe, Mark E. DeVries
Publikováno v:
Developmental and Comparative Immunology
Summary Ferrets ( Mustela putorius furo ) develop symptoms upon influenza infection that resemble those of humans, including sneezing, body temperature variation and weight loss. Highly pathogenic strains of influenza A, such as H5N1, have the capaci
Autor:
Erling W. Rud, Luoling Xu, Steven E. Bosinger, Jocelyn Fournier, Longsi Ran, Monique Parenteau, Karoline A. Hosiawa, Mark J. Cameron, Mohamed R. Boulassel, David J. Kelvin, Desmond Persad
Publikováno v:
The Journal of Immunology. 173:6858-6863
HIV infection is characterized by a host response composed of adaptive and innate immunity that partially limits viral replication; however, it ultimately fails in eradicating the virus. To model host gene expression during acute HIV infection, we in