Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Luodan Liang"'
Autor:
Yonggao Mou, Zhenghe Chen, Shuya Hou, Yuting Jiang, Sheng Zhong, Gaojing Dou, Zhen Guo, Xinhui Wang, Xiaoxia Liu, Xiaye Lv, Bo Wu, Hongyu Wang, Luodan Liang
Objective To screen ideal lead compounds with potential inhibition of 3-phosphoinositi-dependent protein kinase 1 (PDK1) from ZINC15 database, which is beneficial to drug design and improvement.Methods The Discovery Studio 4.5 computer-aided virtual
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea08e3137d905e14a94e3916a94c5caa
https://doi.org/10.21203/rs.3.rs-579921/v1
https://doi.org/10.21203/rs.3.rs-579921/v1
Publikováno v:
Neuroscience letters. 708
Although cerebral vascular smooth muscle cell (VSMC) phenotypic switching is involved in the vascular dysfunction after subarachnoid haemorrhage (SAH), the precise mechanisms are still unclear. High mobility group box-1 (HMGB1) has been identified as