Effects of propofol on the dopamine, metabolites and GABAA receptors in media prefrontal cortex in freely moving rats

Autor: Wang, Yuan, Yu, Tian, Yuan, Chengdong, Yuan, Jie, Luo, Zhuxin, Pan, Yunchao, Zhang, Yi, Zhang, Yu, Yu, Buwei

Recent researches indicate that the mechanism of anesthetic induce loss of consciousness (LOC) is related to dopamine dysfunction in the media prefrontal cortex (mPFC). Given GABAA receptors are the main target for commonly intravenous anesthetic pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::666e7ba3e9657a8f1302010a07069eec
https://europepmc.org/articles/PMC4891442/

Effects of propofol on the dopamine, metabolites and GABAA receptors in media prefrontal cortex in freely moving rats.

Autor: Wang Y; Department of Anesthesiology, Ruijin Hospital, Shanghai Jiao Tong University School of MedicineShanghai, China; Guizhou Key Laboratory of Anesthesia and Organ Protection, Zunyi Medical CollegeZunyi, Guizhou, China., Yu T; Guizhou Key Laboratory of Anesthesia and Organ Protection, Zunyi Medical College Zunyi, Guizhou, China., Yuan C; Guizhou Key Laboratory of Anesthesia and Organ Protection, Zunyi Medical College Zunyi, Guizhou, China., Yuan J; Guizhou Key Laboratory of Anesthesia and Organ Protection, Zunyi Medical College Zunyi, Guizhou, China., Luo Z; Guizhou Key Laboratory of Anesthesia and Organ Protection, Zunyi Medical College Zunyi, Guizhou, China., Pan Y; Guizhou Key Laboratory of Anesthesia and Organ Protection, Zunyi Medical College Zunyi, Guizhou, China., Zhang Y; Guizhou Key Laboratory of Anesthesia and Organ Protection, Zunyi Medical College Zunyi, Guizhou, China., Zhang Y; Guizhou Key Laboratory of Anesthesia and Organ Protection, Zunyi Medical College Zunyi, Guizhou, China., Yu B; Department of Anesthesiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine Shanghai, China.

Publikováno v: American journal of translational research [Am J Transl Res] 2016 May 15; Vol. 8 (5), pp. 2301-8. Date of Electronic Publication: 2016 May 15 (Print Publication: 2016).