Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Luning Zhuang"'
Autor:
Richard Pazdur, Ann T. Farrell, Kirsten B. Goldberg, Ruby Leong, Chao Liu, Christopher M. Sheth, Yuan-Li Shen, Donna Przepiorka, Pedro L. Del Valle, Luning Zhuang, Sriram Subramaniam, Kunthel By, Kelly J. Norsworthy
Supplementary Figure 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40f695b031ea2746b3b535c50a6f75f0
https://doi.org/10.1158/1078-0432.22472658.v1
https://doi.org/10.1158/1078-0432.22472658.v1
Autor:
Richard Pazdur, Ann T. Farrell, Kirsten B. Goldberg, Ruby Leong, Chao Liu, Christopher M. Sheth, Yuan-Li Shen, Donna Przepiorka, Pedro L. Del Valle, Luning Zhuang, Sriram Subramaniam, Kunthel By, Kelly J. Norsworthy
Supplementary Table S2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::662c2fafd3def9de60e42b7af6e56a78
https://doi.org/10.1158/1078-0432.22472652.v1
https://doi.org/10.1158/1078-0432.22472652.v1
Autor:
Richard Pazdur, Ann T. Farrell, Kirsten B. Goldberg, Ruby Leong, Chao Liu, Christopher M. Sheth, Yuan-Li Shen, Donna Przepiorka, Pedro L. Del Valle, Luning Zhuang, Sriram Subramaniam, Kunthel By, Kelly J. Norsworthy
Supplementary Table S1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77f7c389244ff34327770c1c37b2a2de
https://doi.org/10.1158/1078-0432.22472655
https://doi.org/10.1158/1078-0432.22472655
Autor:
Richard Pazdur, Gideon M. Blumenthal, Ann T. Farrell, Kirsten B. Goldberg, Steven Bowen, Christopher M. Sheth, Chao Liu, Ruby Leong, Yuan Li Shen, Donna Przepiorka, Rong Wang, Baikuntha Aryal, Natalie E. Simpson, Luning Zhuang, Liang Li, Xin Gao, Emily Y. Jen
Supplementary Table 1 contains FDA's screening algorithm for capillary leak syndrome (CLS).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23ed8d0ff75dab154150f0380e96edf0
https://doi.org/10.1158/1078-0432.22476914.v1
https://doi.org/10.1158/1078-0432.22476914.v1
Autor:
Richard Pazdur, Ann T. Farrell, Kirsten B. Goldberg, Ruby Leong, Chao Liu, Christopher M. Sheth, Yuan-Li Shen, Donna Przepiorka, Pedro L. Del Valle, Luning Zhuang, Sriram Subramaniam, Kunthel By, Kelly J. Norsworthy
On November 21, 2018, the FDA approved glasdegib (Daurismo; Pfizer), a small-molecule Hedgehog inhibitor, in combination with low-dose cytarabine (LDAC) for treatment of newly diagnosed acute myeloid leukemia (AML) in adults ≥ 75 years or with como
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caa9d058c026a5b87d84c0288f1eb1b1
https://doi.org/10.1158/1078-0432.c.6528291
https://doi.org/10.1158/1078-0432.c.6528291
Autor:
Richard Pazdur, Gideon M. Blumenthal, Ann T. Farrell, Kirsten B. Goldberg, Steven Bowen, Christopher M. Sheth, Chao Liu, Ruby Leong, Yuan Li Shen, Donna Przepiorka, Rong Wang, Baikuntha Aryal, Natalie E. Simpson, Luning Zhuang, Liang Li, Xin Gao, Emily Y. Jen
Tagraxofusp-erzs (Elzonris, Stemline) is a cytotoxin that targets CD123-expressing cells. On December 21, 2018, FDA approved tagraxofusp-erzs for the treatment of blastic plasmacytoid dendritic cell neoplasms (BPDCN) in adult and pediatric patients 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f4b2d8a53c69b4c65849d1eebfa9190
https://doi.org/10.1158/1078-0432.c.6529523
https://doi.org/10.1158/1078-0432.c.6529523
Publikováno v:
Antimicrob Agents Chemother
In 2018, the FDA approved plazomicin for the treatment of complicated urinary tract infections (cUTI) including pyelonephritis in adult patients with limited or no alternative treatment options. The objective of this article is to provide the scienti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc2d07787ab51cb43b6e8aae9fc43f46
https://europepmc.org/articles/PMC9017347/
https://europepmc.org/articles/PMC9017347/
Autor:
Kellie S. Reynolds, Yaning Wang, Jeffry Florian, Seong H. Jang, Yichao Yu, Xiaohui Wei, Luning Zhuang
Publikováno v:
The Journal of Clinical Pharmacology. 60:1011-1021
The objectives of this study were to evaluate the effect of hemodialysis (HD) on the pharmacokinetics (PK) of meropenem/vaborbactam, an approved beta-lactam/beta-lactamase inhibitor combination, and provide the rationale for the recommended timing of
Autor:
Jingyu Yu, Janet Maynard, Gilbert J. Burckart, Jianmeng Chen, Anshu Marathe, Mark Borigini, Luning Zhuang, Yaning Wang, Chandra Sahajwalla
Publikováno v:
Clinical Pharmacology & Therapeutics. 106:557-567
Periodic fever syndromes are a group of rare diseases with a highly variable onset, yet limited treatment options are available for children at an early age. Canakinumab has been approved to treat patients with cryopyrin-associated periodic syndrome,
Autor:
Justin C. Earp, Yaning Wang, Fang Li, Yuching Yang, Michael Bewernitz, Jingyu Yu, Xinyuan Zhang, Ruo-Jing Li, Luning Zhuang, Youwei Bi, Jiang Liu, Atul Bhattaram, Lian Ma, Hao Zhu, Jihye Ahn
Publikováno v:
Journal of clinical pharmacologyReferences. 61
Model-informed drug development (MIDD) has been a powerful and efficient tool applied widely in pediatric drug development due to its ability to integrate and leverage existing knowledge from different sources to narrow knowledge gaps. The dose selec