Quantifying full-length circular RNAs in cancer.

Autor: Yu KH; Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong.; Department of Computer Science and Engineering, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong., Shi CH; Department of Computer Science and Engineering, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong., Wang B; Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong., Chow SH; Department of Computer Science and Engineering, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong.; School of Life Sciences, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong., Chung GT; Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong., Lung RW; Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong., Tan KE; Institute of Biological Sciences, Faculty of Science, University of Malaya, Kuala Lumpur 50603, Malaysia., Lim YY; Institute of Biological Sciences, Faculty of Science, University of Malaya, Kuala Lumpur 50603, Malaysia., Tsang AC; Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong., Lo KW; Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong., Yip KY; Department of Computer Science and Engineering, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong.; Hong Kong Bioinformatics Centre, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong.; Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong.

Publikováno v: Genome research [Genome Res] 2021 Dec; Vol. 31 (12), pp. 2340-2353. Date of Electronic Publication: 2021 Oct 18.

Distinct Molecular Landscape of Epstein-Barr Virus Associated Pulmonary Lymphoepithelioma-Like Carcinoma Revealed by Genomic Sequencing.

Autor: Chau SL; Department of Anatomical and Cellular Pathology, State Key Laboratory of Translational Oncology, The Chinese University of Hong Kong, Hong Kong, China.; Sir Y.K. Pao Cancer Center, The Chinese University of Hong Kong, Hong Kong, China., Tong JH; Department of Anatomical and Cellular Pathology, State Key Laboratory of Translational Oncology, The Chinese University of Hong Kong, Hong Kong, China.; Sir Y.K. Pao Cancer Center, The Chinese University of Hong Kong, Hong Kong, China., Chow C; Department of Anatomical and Cellular Pathology, State Key Laboratory of Translational Oncology, The Chinese University of Hong Kong, Hong Kong, China.; Sir Y.K. Pao Cancer Center, The Chinese University of Hong Kong, Hong Kong, China., Kwan JS; Department of Anatomical and Cellular Pathology, State Key Laboratory of Translational Oncology, The Chinese University of Hong Kong, Hong Kong, China.; Sir Y.K. Pao Cancer Center, The Chinese University of Hong Kong, Hong Kong, China., Lung RW; Department of Anatomical and Cellular Pathology, State Key Laboratory of Translational Oncology, The Chinese University of Hong Kong, Hong Kong, China.; Sir Y.K. Pao Cancer Center, The Chinese University of Hong Kong, Hong Kong, China., Chung LY; Department of Anatomical and Cellular Pathology, State Key Laboratory of Translational Oncology, The Chinese University of Hong Kong, Hong Kong, China.; Sir Y.K. Pao Cancer Center, The Chinese University of Hong Kong, Hong Kong, China., Tin EK; Department of Anatomical and Cellular Pathology, State Key Laboratory of Translational Oncology, The Chinese University of Hong Kong, Hong Kong, China.; Sir Y.K. Pao Cancer Center, The Chinese University of Hong Kong, Hong Kong, China., Wong SS; Department of Anatomical and Cellular Pathology, State Key Laboratory of Translational Oncology, The Chinese University of Hong Kong, Hong Kong, China.; Sir Y.K. Pao Cancer Center, The Chinese University of Hong Kong, Hong Kong, China., Cheung AH; Department of Anatomical and Cellular Pathology, State Key Laboratory of Translational Oncology, The Chinese University of Hong Kong, Hong Kong, China.; Sir Y.K. Pao Cancer Center, The Chinese University of Hong Kong, Hong Kong, China., Lau RW; Division of Cardiothoracic Surgery, Department of Surgery, The Chinese University of Hong Kong, Hong Kong, China., Ng CS; Division of Cardiothoracic Surgery, Department of Surgery, The Chinese University of Hong Kong, Hong Kong, China., Mok TS; Department of Clinical Oncology, The Chinese University of Hong Kong, Hong Kong, China., Lo KW; Department of Anatomical and Cellular Pathology, State Key Laboratory of Translational Oncology, The Chinese University of Hong Kong, Hong Kong, China.; Sir Y.K. Pao Cancer Center, The Chinese University of Hong Kong, Hong Kong, China., To KF; Department of Anatomical and Cellular Pathology, State Key Laboratory of Translational Oncology, The Chinese University of Hong Kong, Hong Kong, China.; Sir Y.K. Pao Cancer Center, The Chinese University of Hong Kong, Hong Kong, China.

Publikováno v: Cancers [Cancers (Basel)] 2020 Jul 27; Vol. 12 (8). Date of Electronic Publication: 2020 Jul 27.

The Landscape of Actionable Molecular Alterations in Immunomarker-Defined Large-Cell Carcinoma of the Lung.

Autor: Chan AW; Department of Anatomical and Cellular Pathology, State Key Laboratory of Translational Oncology, the Chinese University of Hong Kong, Hong Kong, China; Li Ka-Shing Institute of Health Sciences, Sir Y.K. Pao Cancer Center, the Chinese University of Hong Kong, Hong Kong, China; Institute of Digestive Disease, State Key Laboratory of Digestive Disease, the Chinese University of Hong Kong, Hong Kong, China., Chau SL; Department of Anatomical and Cellular Pathology, State Key Laboratory of Translational Oncology, the Chinese University of Hong Kong, Hong Kong, China; Li Ka-Shing Institute of Health Sciences, Sir Y.K. Pao Cancer Center, the Chinese University of Hong Kong, Hong Kong, China; Institute of Digestive Disease, State Key Laboratory of Digestive Disease, the Chinese University of Hong Kong, Hong Kong, China., Tong JH; Department of Anatomical and Cellular Pathology, State Key Laboratory of Translational Oncology, the Chinese University of Hong Kong, Hong Kong, China; Li Ka-Shing Institute of Health Sciences, Sir Y.K. Pao Cancer Center, the Chinese University of Hong Kong, Hong Kong, China; Institute of Digestive Disease, State Key Laboratory of Digestive Disease, the Chinese University of Hong Kong, Hong Kong, China., Chow C; Department of Anatomical and Cellular Pathology, State Key Laboratory of Translational Oncology, the Chinese University of Hong Kong, Hong Kong, China; Li Ka-Shing Institute of Health Sciences, Sir Y.K. Pao Cancer Center, the Chinese University of Hong Kong, Hong Kong, China; Institute of Digestive Disease, State Key Laboratory of Digestive Disease, the Chinese University of Hong Kong, Hong Kong, China., Kwan JSH; Department of Anatomical and Cellular Pathology, State Key Laboratory of Translational Oncology, the Chinese University of Hong Kong, Hong Kong, China; Li Ka-Shing Institute of Health Sciences, Sir Y.K. Pao Cancer Center, the Chinese University of Hong Kong, Hong Kong, China; Institute of Digestive Disease, State Key Laboratory of Digestive Disease, the Chinese University of Hong Kong, Hong Kong, China., Chung LY; Department of Anatomical and Cellular Pathology, State Key Laboratory of Translational Oncology, the Chinese University of Hong Kong, Hong Kong, China; Li Ka-Shing Institute of Health Sciences, Sir Y.K. Pao Cancer Center, the Chinese University of Hong Kong, Hong Kong, China; Institute of Digestive Disease, State Key Laboratory of Digestive Disease, the Chinese University of Hong Kong, Hong Kong, China., Lung RW; Department of Anatomical and Cellular Pathology, State Key Laboratory of Translational Oncology, the Chinese University of Hong Kong, Hong Kong, China; Li Ka-Shing Institute of Health Sciences, Sir Y.K. Pao Cancer Center, the Chinese University of Hong Kong, Hong Kong, China; Institute of Digestive Disease, State Key Laboratory of Digestive Disease, the Chinese University of Hong Kong, Hong Kong, China., Tong CY; Department of Anatomical and Cellular Pathology, State Key Laboratory of Translational Oncology, the Chinese University of Hong Kong, Hong Kong, China; Li Ka-Shing Institute of Health Sciences, Sir Y.K. Pao Cancer Center, the Chinese University of Hong Kong, Hong Kong, China; Institute of Digestive Disease, State Key Laboratory of Digestive Disease, the Chinese University of Hong Kong, Hong Kong, China., Tin EK; Department of Anatomical and Cellular Pathology, State Key Laboratory of Translational Oncology, the Chinese University of Hong Kong, Hong Kong, China; Li Ka-Shing Institute of Health Sciences, Sir Y.K. Pao Cancer Center, the Chinese University of Hong Kong, Hong Kong, China; Institute of Digestive Disease, State Key Laboratory of Digestive Disease, the Chinese University of Hong Kong, Hong Kong, China., Law PP; Department of Anatomical and Cellular Pathology, State Key Laboratory of Translational Oncology, the Chinese University of Hong Kong, Hong Kong, China; Li Ka-Shing Institute of Health Sciences, Sir Y.K. Pao Cancer Center, the Chinese University of Hong Kong, Hong Kong, China; Institute of Digestive Disease, State Key Laboratory of Digestive Disease, the Chinese University of Hong Kong, Hong Kong, China., Law WT; Department of Anatomical and Cellular Pathology, State Key Laboratory of Translational Oncology, the Chinese University of Hong Kong, Hong Kong, China; Li Ka-Shing Institute of Health Sciences, Sir Y.K. Pao Cancer Center, the Chinese University of Hong Kong, Hong Kong, China; Institute of Digestive Disease, State Key Laboratory of Digestive Disease, the Chinese University of Hong Kong, Hong Kong, China., Ng CSH; Division of Cardiothoracic Surgery, Department of Surgery, the Chinese University of Hong Kong, Hong Kong, China., Wan IYP; Division of Cardiothoracic Surgery, Department of Surgery, the Chinese University of Hong Kong, Hong Kong, China., Mok TSK; Department of Clinical Oncology, State Key Laboratory of Translational Oncology, the Chinese University of Hong Kong, Hong Kong, China., To KF; Department of Anatomical and Cellular Pathology, State Key Laboratory of Translational Oncology, the Chinese University of Hong Kong, Hong Kong, China; Li Ka-Shing Institute of Health Sciences, Sir Y.K. Pao Cancer Center, the Chinese University of Hong Kong, Hong Kong, China; Institute of Digestive Disease, State Key Laboratory of Digestive Disease, the Chinese University of Hong Kong, Hong Kong, China. Electronic address: kfto@cuhk.edu.hk.

Publikováno v: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer [J Thorac Oncol] 2019 Jul; Vol. 14 (7), pp. 1213-1222. Date of Electronic Publication: 2019 Apr 09.

Aberrant enhancer hypomethylation contributes to hepatic carcinogenesis through global transcriptional reprogramming.

Autor: Xiong L; Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Hong Kong SAR, China.; School of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China., Wu F; Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Hong Kong SAR, China.; School of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China., Wu Q; School of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China., Xu L; School of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China., Cheung OK; School of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China., Kang W; Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Hong Kong SAR, China., Mok MT; School of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China., Szeto LLM; School of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China., Lun CY; School of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China., Lung RW; Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Hong Kong SAR, China., Zhang J; Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Hong Kong SAR, China., Yu KH; Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Hong Kong SAR, China.; Department of Computer Science and Engineering, The Chinese University of Hong Kong, Hong Kong SAR, China., Lee SD; Department of Computer Science and Engineering, The Chinese University of Hong Kong, Hong Kong SAR, China., Huang G; Department of Molecular Medicine, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78245, USA., Wang CM; Department of Molecular Medicine, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78245, USA., Liu J; Department of Molecular Medicine, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78245, USA., Yu Z; Department of Liver Disease, Shuguang Hospital affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China., Yu DY; Disease Model Research Laboratory, Genome Editing Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 305-806, Republic of Korea., Chou JL; Department of Biomedical Sciences, National Chung Cheng University, Chia-Yi 62102, Taiwan, Republic of China., Huang WH; Department of Biomedical Sciences, National Chung Cheng University, Chia-Yi 62102, Taiwan, Republic of China., Feng B; School of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China., Cheung YS; Department of Surgery, The Chinese University of Hong Kong, Hong Kong SAR, China., Lai PB; Department of Surgery, The Chinese University of Hong Kong, Hong Kong SAR, China., Tan P; Program in Cancer and Stem Cell Biology, Duke-NUS Medical School, Singapore 169857, Singapore.; Genome Institute of Singapore, Singapore 138672, Singapore., Wong N; Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Hong Kong SAR, China., Chan MW; Department of Biomedical Sciences, National Chung Cheng University, Chia-Yi 62102, Taiwan, Republic of China., Huang TH; Department of Molecular Medicine, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78245, USA., Yip KY; Department of Computer Science and Engineering, The Chinese University of Hong Kong, Hong Kong SAR, China. kevinyip@cse.cuhk.edu.hk., Cheng AS; School of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China. alfredcheng@cuhk.edu.hk., To KF; Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Hong Kong SAR, China. kfto@cuhk.edu.hk.; State Key Laboratory of Translational Oncology, The Chinese University of Hong Kong, Hong Kong SAR, China. kfto@cuhk.edu.hk.

Publikováno v: Nature communications [Nat Commun] 2019 Jan 18; Vol. 10 (1), pp. 335. Date of Electronic Publication: 2019 Jan 18.

EBV-encoded miRNAs target ATM-mediated response in nasopharyngeal carcinoma.

Autor: Lung RW; Department of Anatomical and Cellular Pathology, State Key Laboratory in Oncology in South China and Li Ka Shing Institute of Health Science, The Chinese University of Hong Kong, Hong Kong., Hau PM; Department of Anatomical and Cellular Pathology, State Key Laboratory in Oncology in South China and Li Ka Shing Institute of Health Science, The Chinese University of Hong Kong, Hong Kong., Yu KH; Department of Computer Science and Engineering, The Chinese University of Hong Kong, Hong Kong., Yip KY; Department of Computer Science and Engineering, The Chinese University of Hong Kong, Hong Kong., Tong JH; Department of Anatomical and Cellular Pathology, State Key Laboratory in Oncology in South China and Li Ka Shing Institute of Health Science, The Chinese University of Hong Kong, Hong Kong., Chak WP; Department of Anatomical and Cellular Pathology, State Key Laboratory in Oncology in South China and Li Ka Shing Institute of Health Science, The Chinese University of Hong Kong, Hong Kong., Chan AW; Department of Anatomical and Cellular Pathology, State Key Laboratory in Oncology in South China and Li Ka Shing Institute of Health Science, The Chinese University of Hong Kong, Hong Kong., Lam KH; Department of Anatomical and Cellular Pathology, State Key Laboratory in Oncology in South China and Li Ka Shing Institute of Health Science, The Chinese University of Hong Kong, Hong Kong., Lo AK; Department of Anatomical and Cellular Pathology, State Key Laboratory in Oncology in South China and Li Ka Shing Institute of Health Science, The Chinese University of Hong Kong, Hong Kong., Tin EK; Department of Anatomical and Cellular Pathology, State Key Laboratory in Oncology in South China and Li Ka Shing Institute of Health Science, The Chinese University of Hong Kong, Hong Kong., Chau SL; Department of Anatomical and Cellular Pathology, State Key Laboratory in Oncology in South China and Li Ka Shing Institute of Health Science, The Chinese University of Hong Kong, Hong Kong., Pang JC; Department of Anatomical and Cellular Pathology, State Key Laboratory in Oncology in South China and Li Ka Shing Institute of Health Science, The Chinese University of Hong Kong, Hong Kong., Kwan JS; Department of Anatomical and Cellular Pathology, State Key Laboratory in Oncology in South China and Li Ka Shing Institute of Health Science, The Chinese University of Hong Kong, Hong Kong., Busson P; UMR8126 CNRS, Université Paris-Sud, Université Paris-Saclay, Gustave Roussy, Villejuif, France., Young LS; Warwick Medical School, University of Warwick, Coventry, UK., Yap LF; Department of Oral and Craniofacial Sciences and Oral Cancer Research and Coordinating Centre, Faculty of Dentistry, University of Malaya, Kuala Lumpur, Malaysia., Tsao SW; School of Biomedical Sciences and Center for Cancer Research, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong., To KF; Department of Anatomical and Cellular Pathology, State Key Laboratory in Oncology in South China and Li Ka Shing Institute of Health Science, The Chinese University of Hong Kong, Hong Kong., Lo KW; Department of Anatomical and Cellular Pathology, State Key Laboratory in Oncology in South China and Li Ka Shing Institute of Health Science, The Chinese University of Hong Kong, Hong Kong.

Publikováno v: The Journal of pathology [J Pathol] 2018 Apr; Vol. 244 (4), pp. 394-407. Date of Electronic Publication: 2018 Feb 16.