Mechanical stimulation modulates osteocyte regulation of cancer cell phenotype

Autor: Verbruggen, S.W., Thompson, C.L., Duffy, M.P., Lunetto, S., Nolan, J., Pearce, O.M.T., Jacobs, C.R., Knight, M.M.

Breast and prostate cancers preferentially metastasise to bone tissue, with metastatic lesions forming in the skeletons of most patients. On arriving in bone tissue, disseminated tumour cells enter a mechanical microenvironment that is substantially

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::1662ad0798cc1788a24e9bd5da5e9d50

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Mechanical Stimulation Modulates Osteocyte Regulation of Cancer Cell Phenotype.

Autor: Verbruggen SW; Department of Biomedical Engineering, Columbia University in the City of New York, New York, NY 10027, USA.; Centre for Predictive in vitro Models, School of Engineering and Materials Science, Queen Mary University of London, London E1 4NS, UK.; Department of Mechanical Engineering and INSIGNEO Institute for in silico Medicine, University of Sheffield, Sheffield S1 3JD, UK., Thompson CL; Centre for Predictive in vitro Models, School of Engineering and Materials Science, Queen Mary University of London, London E1 4NS, UK.; Queen Mary + Emulate Organs-on-Chips Centre, Queen Mary University of London, London E1 4NS, UK., Duffy MP; Department of Biomedical Engineering, Columbia University in the City of New York, New York, NY 10027, USA., Lunetto S; Centre for Predictive in vitro Models, School of Engineering and Materials Science, Queen Mary University of London, London E1 4NS, UK., Nolan J; Centre for Predictive in vitro Models, School of Engineering and Materials Science, Queen Mary University of London, London E1 4NS, UK.; Queen Mary + Emulate Organs-on-Chips Centre, Queen Mary University of London, London E1 4NS, UK.; Barts Cancer Institute, School of Medicine and Dentistry, Queen Mary University of London, London EC1M 5PZ, UK., Pearce OMT; Barts Cancer Institute, School of Medicine and Dentistry, Queen Mary University of London, London EC1M 5PZ, UK., Jacobs CR; Department of Biomedical Engineering, Columbia University in the City of New York, New York, NY 10027, USA., Knight MM; Centre for Predictive in vitro Models, School of Engineering and Materials Science, Queen Mary University of London, London E1 4NS, UK.; Queen Mary + Emulate Organs-on-Chips Centre, Queen Mary University of London, London E1 4NS, UK.

Publikováno v: Cancers [Cancers (Basel)] 2021 Jun 10; Vol. 13 (12). Date of Electronic Publication: 2021 Jun 10.