Discovery of a nonpeptidic small molecule antagonist of the human platelet thrombin receptor (PAR-1)

Autor: Nantermet, Philippe G, Barrow, James C, Lundell, George F, Pellicore, Janetta M, Rittle, Kenneth E, Young, MaryBeth, Freidinger, Roger M, Connolly, Thomas M, Condra, Cindra, Karczewski, Jerzy, Bednar, Rodney A, Gaul, Stanley L, Gould, Robert J, Prendergast, Kris, Selnick, Harold G

Publikováno v: In Bioorganic & Medicinal Chemistry Letters 2002 12(3):319-323

Discovery and evaluation of potent P1 aryl heterocycle-based thrombin inhibitors.

Autor: Young MB; Medicinal Chemistry, Merck Research Laboratories, Merck and Co., Inc., WP14-3, Post Office Box 4, Sumneytown Pike, West Point, PA 19486, USA. mary_beth_young@merck.com, Barrow JC, Glass KL, Lundell GF, Newton CL, Pellicore JM, Rittle KE, Selnick HG, Stauffer KJ, Vacca JP, Williams PD, Bohn D, Clayton FC, Cook JJ, Krueger JA, Kuo LC, Lewis SD, Lucas BJ, McMasters DR, Miller-Stein C, Pietrak BL, Wallace AA, White RB, Wong B, Yan Y, Nantermet PG

Publikováno v: Journal of medicinal chemistry [J Med Chem] 2004 Jun 03; Vol. 47 (12), pp. 2995-3008.