Integrative analyses reveal outcome-associated and targetable molecular partnerships between TP53, BRD4, TNFRSF10B, and CDKN1A in diffuse large B-cell lymphoma.

Autor: Forberg, Aidan L., Unrau, Jordan, Weber, Kennedee S., Rutz, Alison C., Lund, Shelby, Guidinger, Jinda, Pelzel, Andrew, Hauge, Jackson, Hemmen, Ainslee J., Hartert, Keenan T.

Publikováno v: Annals of Hematology; Jan2024, Vol. 103 Issue 1, p199-209, 11p

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

EFS24 Failure, BRD4 Expression, and TP53 Are Linked to Reduced CDKN1A Expression in DLBCL and May be Targeted By Single-Agent Protac ARV-825 or in Synergistic Combination with the CDK4/6 Inhibitor Abemaciclib

Autor: Rutz, Alison ^*, Weber, Kennedee ^*, Lund, Shelby ^*, Guidinger, Jinda ^*, Forberg, Aidan ^*, Hartert, Keenan T.

Publikováno v: In Blood 15 November 2022 140 Supplement 1:3525-3526

Enrichment of TP53 alterations within GCB-like DNA subclassifications of diffuse large B-cell lymphoma after transition from de-novo to relapsed or refractory disease.

Autor: Lund S; Department of Biological Sciences, College of Science Engineering and Technology, Minnesota State University Mankato, Mankato, MN, USA., Ngisa V; Department of Biological Sciences, College of Science Engineering and Technology, Minnesota State University Mankato, Mankato, MN, USA., Weber K; Department of Biological Sciences, College of Science Engineering and Technology, Minnesota State University Mankato, Mankato, MN, USA., Rutz A; Department of Biological Sciences, College of Science Engineering and Technology, Minnesota State University Mankato, Mankato, MN, USA., Guidinger J; Department of Biological Sciences, College of Science Engineering and Technology, Minnesota State University Mankato, Mankato, MN, USA., Hartert KT; Department of Biological Sciences, College of Science Engineering and Technology, Minnesota State University Mankato, Mankato, MN, USA.

Publikováno v: Blood research [Blood Res] 2022 Jun 30; Vol. 57 (2), pp. 164-169. Date of Electronic Publication: 2022 May 13.