Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Luna Benvenisti-Zarom"'
Publikováno v:
Neurobiology of Disease, Vol 31, Iss 2, Pp 242-249 (2008)
The effect of iron regulatory protein-2 (IRP2) on ferritin expression and neuronal vulnerability to hemoglobin was assessed in primary cortical cell cultures prepared from wild-type and IRP2 knockout mice. Baseline levels of H and L-ferritin subunits
Externí odkaz:
https://doaj.org/article/08df20c8b57c4e96b4bdecd01a1e8291
Publikováno v:
Neurobiology of Disease, Vol 26, Iss 3, Pp 688-695 (2007)
In prior studies, we have observed that HO activity protects astrocytes from heme-mediated injury, but paradoxically increases neuronal injury. In this study, we tested the hypothesis that an adenovirus encoding the human HO-1 gene driven by an enhan
Externí odkaz:
https://doaj.org/article/388a05678661495c90d1edb1ddfe6410
Publikováno v:
Neurobiology of Disease, Vol 31, Iss 2, Pp 242-249 (2008)
The effect of iron regulatory protein-2 (IRP2) on ferritin expression and neuronal vulnerability to hemoglobin was assessed in primary cortical cell cultures prepared from wild-type and IRP2 knockout mice. Baseline levels of H and L-ferritin subunits
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9eba6ffa590b7baca1a4bfcd1fe5f7d
https://doi.org/10.1016/j.nbd.2008.04.008
https://doi.org/10.1016/j.nbd.2008.04.008
Publikováno v:
Journal of Neurosurgery. 106:428-435
Object Experimental evidence suggests that hemoglobin degradation products contribute to cellular injury after intracerebal hemorrhage (ICH). Hemoglobin breakdown is catalyzed in part by the heme oxygenase (HO) enzymes. In the present study, the auth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86172240df3aae552199658b5d770b59
https://doi.org/10.3171/jns.2007.106.3.428
https://doi.org/10.3171/jns.2007.106.3.428
Publikováno v:
Neuroscience Letters. 398:230-234
Hemin is an oxidant that accumulates in intracranial hematomas. Its neurotoxicity is increased by its breakdown, which is catalyzed by the heme oxygenase (HO) enzymes. In this study we tested the hypothesis that inhibiting signaling events mediating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f528a0d3f1860f9987f194cc4974907
https://doi.org/10.1016/j.neulet.2006.01.003
https://doi.org/10.1016/j.neulet.2006.01.003
Publikováno v:
Neuropharmacology. 49:687-694
Clioquinol is a metal chelator that may attenuate beta-amyloid deposition and mitigate the progression of Alzheimer's disease. Its prior use as a systemic antibiotic was associated with a neurodegenerative syndrome, subacute myelo-optico-neuropathy (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3de7bdcc7067e93d3d7e28d4971c1afd
https://doi.org/10.1016/j.neuropharm.2005.04.023
https://doi.org/10.1016/j.neuropharm.2005.04.023
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 25:1466-1475
The heme oxygenase (HO) enzymes catalyze the rate-limiting step in the breakdown of heme to iron, carbon monoxide, and biliverdin. A prior cell culture study demonstrated that deletion of HO-2, the isoform constitutively expressed in neurons, attenua
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ae3fc94fff52a983ce6ba7d7392ab43
https://doi.org/10.1038/sj.jcbfm.9600143
https://doi.org/10.1038/sj.jcbfm.9600143
Publikováno v:
Journal of neuroscience research. 82(6)
Hemin, the oxidized form of heme, is released from hemoglobin after CNS hemorrhage and may contribute to injury to surrounding tissue. The heme oxygenase (HO) enzymes catalyze the breakdown of hemin to biliverdin, carbon monoxide, and ferric iron. Al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73748e1117666ff6b4e9345aebe555b2
https://pubmed.ncbi.nlm.nih.gov/16273550
https://pubmed.ncbi.nlm.nih.gov/16273550
Publikováno v:
BMC Neuroscience. 5:34
Background: Hemin, the oxidized form of heme, accumulates in intracranial hematomas and is a potent oxidant. Growing evidence suggests that it contributes to delayed injury to surrounding tissue, and that this process is affected by the heme oxygenas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33628bcb694a6c5580caa78d411efcee
https://doi.org/10.1186/1471-2202-5-34
https://doi.org/10.1186/1471-2202-5-34
Publikováno v:
Journal of Neuroscience Research; Dec2005, Vol. 82 Issue 6, p802-810, 0p