MEIS-WNT5A axis regulates development of fourth ventricle choroid plexus.

Autor: Kaiser K; Department of Experimental Biology, Faculty of Science, Masaryk University, Brno 61137, Czech Republic., Jang A; Department of Pathology, Boston Children's Hospital, Boston, MA 02115, USA., Kompanikova P; Department of Experimental Biology, Faculty of Science, Masaryk University, Brno 61137, Czech Republic., Lun MP; Department of Pathology, Boston Children's Hospital, Boston, MA 02115, USA., Prochazka J; Czech Centre for Phenogenomics and Laboratory of Transgenic Models of Diseases, Institute of Molecular Genetics of the CAS, Prague 142 20, Czech Republic., Machon O; Laboratory of Transcriptional Regulation, Institute of Molecular Genetics of the CAS, Prague 142 20, Czech Republic., Dani N; Department of Pathology, Boston Children's Hospital, Boston, MA 02115, USA., Prochazkova M; Czech Centre for Phenogenomics and Laboratory of Transgenic Models of Diseases, Institute of Molecular Genetics of the CAS, Prague 142 20, Czech Republic., Laurent B; Research Center on Aging, CIUSSS de l'Estrie - CHUS, Sherbrooke, QC 75361, Canada.; Department of Biochemistry and Functional Genomics, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, QC 75281, Canada., Gyllborg D; Science for Life Laboratory, Department of Biochemistry and Biophysics, Stockholm University, Solna SE-106 91, Sweden., van Amerongen R; Swammerdam Institute for Life Sciences, Section of Molecular Cytology, Faculty of Science, University of Amsterdam1098 XH, Netherlands., Fame RM; Department of Pathology, Boston Children's Hospital, Boston, MA 02115, USA., Gupta S; Department of Pathology, Boston Children's Hospital, Boston, MA 02115, USA., Wu F; Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, China., Barker RA; John van Geest Centre for Brain Repair and WT-MRC Cambridge Stem Cell Centre, University of Cambridge, Cambridge CB2 0PY, UK., Bukova I; Czech Centre for Phenogenomics and Laboratory of Transgenic Models of Diseases, Institute of Molecular Genetics of the CAS, Prague 142 20, Czech Republic., Sedlacek R; Czech Centre for Phenogenomics and Laboratory of Transgenic Models of Diseases, Institute of Molecular Genetics of the CAS, Prague 142 20, Czech Republic., Kozmik Z; Laboratory of Transcriptional Regulation, Institute of Molecular Genetics of the CAS, Prague 142 20, Czech Republic., Arenas E; Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm 171 77, Sweden., Lehtinen MK; Department of Pathology, Boston Children's Hospital, Boston, MA 02115, USA., Bryja V; Department of Experimental Biology, Faculty of Science, Masaryk University, Brno 61137, Czech Republic.

Publikováno v: Development (Cambridge, England) [Development] 2021 May 15; Vol. 148 (10). Date of Electronic Publication: 2021 May 25.

ZNHIT3 is defective in PEHO syndrome, a severe encephalopathy with cerebellar granule neuron loss.

Autor: Anttonen AK; The Folkhälsan Institute of Genetics, Haartmaninkatu 8, 00290 Helsinki, Finland.; Neuroscience Center, University of Helsinki, Viikinkaari 4, 00790 Helsinki, Finland.; Research Programs Unit, Molecular Neurology, University of Helsinki, Haartmaninkatu 8, 00290 Helsinki, Finland.; Medical and Clinical Genetics, University of Helsinki and Helsinki University Hospital, Haartmaninkatu 8, 00290 Helsinki, Finland., Laari A; The Folkhälsan Institute of Genetics, Haartmaninkatu 8, 00290 Helsinki, Finland.; Neuroscience Center, University of Helsinki, Viikinkaari 4, 00790 Helsinki, Finland.; Research Programs Unit, Molecular Neurology, University of Helsinki, Haartmaninkatu 8, 00290 Helsinki, Finland., Kousi M; Center for Human Disease Modeling, Duke University Medical Center, Carmichael Building, 300 North Duke Street, Suite 48-118, Durham, NC 27701, USA., Yang YJ; Division of Genetics, Howard Hughes Medical Institute.; Institute for Molecular Medicine Finland, University of Helsinki, Haartmaninkatu 8, 00290 Helsinki, Finland.; Department of Pediatric Neurology, Children's Hospital, University of Helsinki and Helsinki University Hospital, Lastenlinnantie 2, 00290 Helsinki, Finland., Jääskeläinen T; Institute of Biomedicine, University of Eastern Finland, Yliopistonranta 1, 70210 Kuopio, Finland.; Institute of Dentistry, University of Eastern Finland, Yliopistonranta 1, 70210 Kuopio, Finland., Somer M; The Norio Centre, The Rinnekoti Foundation, Kornetintie 8, 00380 Helsinki, Finland., Siintola E; The Folkhälsan Institute of Genetics, Haartmaninkatu 8, 00290 Helsinki, Finland.; Neuroscience Center, University of Helsinki, Viikinkaari 4, 00790 Helsinki, Finland., Jakkula E; Institute for Molecular Medicine Finland, University of Helsinki, Haartmaninkatu 8, 00290 Helsinki, Finland., Muona M; The Folkhälsan Institute of Genetics, Haartmaninkatu 8, 00290 Helsinki, Finland.; Neuroscience Center, University of Helsinki, Viikinkaari 4, 00790 Helsinki, Finland.; Research Programs Unit, Molecular Neurology, University of Helsinki, Haartmaninkatu 8, 00290 Helsinki, Finland.; Institute for Molecular Medicine Finland, University of Helsinki, Haartmaninkatu 8, 00290 Helsinki, Finland., Tegelberg S; The Folkhälsan Institute of Genetics, Haartmaninkatu 8, 00290 Helsinki, Finland.; Neuroscience Center, University of Helsinki, Viikinkaari 4, 00790 Helsinki, Finland.; Research Programs Unit, Molecular Neurology, University of Helsinki, Haartmaninkatu 8, 00290 Helsinki, Finland., Lönnqvist T; Department of Pediatric Neurology, Children's Hospital, University of Helsinki and Helsinki University Hospital, Lastenlinnantie 2, 00290 Helsinki, Finland., Pihko H; Department of Pediatric Neurology, Children's Hospital, University of Helsinki and Helsinki University Hospital, Lastenlinnantie 2, 00290 Helsinki, Finland., Valanne L; Department of Radiology, HUS Medical Imaging Center, Haartmaninkatu 4, 00290 Helsinki, Finland., Paetau A; Department of Pathology, Helsinki University Hospital, Haartmaninkatu 3, 00290 Helsinki, Finland., Lun MP; Department of Pathology, Boston Children's Hospital, BCH 3108, 300 Longwood Ave., Boston, MA 02115, USA.; Department of Pathology and Laboratory Medicine, Boston University School of Medicine, 670 Albany Street, Boston, MA 02118, USA., Hästbacka J; The Folkhälsan Institute of Genetics, Haartmaninkatu 8, 00290 Helsinki, Finland.; Department of Pediatrics, Children's Hospital, University of Helsinki and Helsinki University Hospital, Stenbäckinkatu 11, 00290 Helsinki, Finland., Kopra O; The Folkhälsan Institute of Genetics, Haartmaninkatu 8, 00290 Helsinki, Finland.; Neuroscience Center, University of Helsinki, Viikinkaari 4, 00790 Helsinki, Finland.; Research Programs Unit, Molecular Neurology, University of Helsinki, Haartmaninkatu 8, 00290 Helsinki, Finland., Joensuu T; The Folkhälsan Institute of Genetics, Haartmaninkatu 8, 00290 Helsinki, Finland.; Neuroscience Center, University of Helsinki, Viikinkaari 4, 00790 Helsinki, Finland.; Research Programs Unit, Molecular Neurology, University of Helsinki, Haartmaninkatu 8, 00290 Helsinki, Finland., Katsanis N; Center for Human Disease Modeling, Duke University Medical Center, Carmichael Building, 300 North Duke Street, Suite 48-118, Durham, NC 27701, USA., Lehtinen MK; Department of Pathology, Boston Children's Hospital, BCH 3108, 300 Longwood Ave., Boston, MA 02115, USA., Palvimo JJ; Institute of Biomedicine, University of Eastern Finland, Yliopistonranta 1, 70210 Kuopio, Finland., Lehesjoki AE; The Folkhälsan Institute of Genetics, Haartmaninkatu 8, 00290 Helsinki, Finland.; Neuroscience Center, University of Helsinki, Viikinkaari 4, 00790 Helsinki, Finland.; Research Programs Unit, Molecular Neurology, University of Helsinki, Haartmaninkatu 8, 00290 Helsinki, Finland.

Publikováno v: Brain : a journal of neurology [Brain] 2017 May 01; Vol. 140 (5), pp. 1267-1279.

Progressive Differentiation and Instructive Capacities of Amniotic Fluid and Cerebrospinal Fluid Proteomes following Neural Tube Closure.

Autor: Chau KF; Department of Pathology, Boston Children's Hospital, Boston, MA 02115, USA; Program in Biological and Biomedical Sciences, Harvard Medical School, Boston, MA 02115, USA., Springel MW; Department of Pathology, Boston Children's Hospital, Boston, MA 02115, USA., Broadbelt KG; Department of Pathology, Boston Children's Hospital, Boston, MA 02115, USA., Park HY; Department of Pathology, Boston Children's Hospital, Boston, MA 02115, USA; Program in Neuroscience, Harvard Medical School, Boston, MA 02115, USA., Topal S; Department of Pathology, Boston Children's Hospital, Boston, MA 02115, USA., Lun MP; Department of Pathology, Boston Children's Hospital, Boston, MA 02115, USA; Department of Pathology and Laboratory Medicine, Boston University School of Medicine, Boston, MA 02118, USA., Mullan H; Department of Pathology, Boston Children's Hospital, Boston, MA 02115, USA., Maynard T; Department of Pharmacology and Physiology, Institute for Neuroscience, The George Washington University School of Medicine and Health Sciences, Washington, DC 20037, USA., Steen H; Department of Pathology, Boston Children's Hospital, Boston, MA 02115, USA., LaMantia AS; Department of Pharmacology and Physiology, Institute for Neuroscience, The George Washington University School of Medicine and Health Sciences, Washington, DC 20037, USA., Lehtinen MK; Department of Pathology, Boston Children's Hospital, Boston, MA 02115, USA; Program in Biological and Biomedical Sciences, Harvard Medical School, Boston, MA 02115, USA; Program in Neuroscience, Harvard Medical School, Boston, MA 02115, USA. Electronic address: maria.lehtinen@childrens.harvard.edu.

Publikováno v: Developmental cell [Dev Cell] 2015 Dec 21; Vol. 35 (6), pp. 789-802.

Spatially heterogeneous choroid plexus transcriptomes encode positional identity and contribute to regional CSF production.

Autor: Lun MP; Department of Pathology, and Department of Pathology and Laboratory Medicine, Boston University School of Medicine, Boston, Massachusetts 02118., Johnson MB; Division of Genetics, Boston Children's Hospital, Boston, Massachusetts 02115., Broadbelt KG; Department of Pathology, and., Watanabe M; Department of Pathology and Laboratory Medicine, University of California Irvine School of Medicine, Irvine, California 92697., Kang YJ; Department of Pathology and Laboratory Medicine, University of California Irvine School of Medicine, Irvine, California 92697., Chau KF; Department of Pathology, and., Springel MW; Department of Pathology, and., Malesz A; Department of Pathology, and., Sousa AM; Department of Neurobiology and Kavli Institute for Neuroscience, Yale School of Medicine, New Haven, Connecticut 06510., Pletikos M; Department of Neurobiology and Kavli Institute for Neuroscience, Yale School of Medicine, New Haven, Connecticut 06510., Adelita T; Department of Pathology, and Department of Biochemistry, Federal University of São Paulo, São Paulo 04039, Brazil, and., Calicchio ML; Department of Pathology, and., Zhang Y; Pulmonary and Critical Care Medicine, Department of Medicine, Washington University, St Louis, Missouri 63110., Holtzman MJ; Pulmonary and Critical Care Medicine, Department of Medicine, Washington University, St Louis, Missouri 63110., Lidov HG; Department of Pathology, and., Sestan N; Department of Neurobiology and Kavli Institute for Neuroscience, Yale School of Medicine, New Haven, Connecticut 06510., Steen H; Department of Pathology, and., Monuki ES; Department of Pathology and Laboratory Medicine, University of California Irvine School of Medicine, Irvine, California 92697., Lehtinen MK; Department of Pathology, and maria.lehtinen@childrens.harvard.edu.

Publikováno v: The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2015 Mar 25; Vol. 35 (12), pp. 4903-16.