Zobrazeno 1 - 10
of 345
pro vyhledávání: '"Lun‑Xiu Qin"'
Autor:
Sun-Zhe Xie, Lu-Yu Yang, Ran Wei, Xiao-Tian Shen, Jun-Jie Pan, Shi-Zhe Yu, Chen Zhang, Hao Xu, Jian-Feng Xu, Xin Zheng, Hao Wang, Ying-Han Su, Hao-Ting Sun, Lu Lu, Ming Lu, Wen-Wei Zhu, Lun-Xiu Qin
Publikováno v:
Experimental Hematology & Oncology, Vol 13, Iss 1, Pp 1-20 (2024)
Abstract Background The mechanisms by which tumor-derived factors remodel the microenvironment of target organs to facilitate cancer metastasis, especially organ-specific metastasis, remains obscure. Our previous studies have demonstrated that SPP1 p
Externí odkaz:
https://doaj.org/article/c210e9263f8945289f5623c97c582f68
Publikováno v:
Journal of Hematology & Oncology, Vol 17, Iss 1, Pp 1-23 (2024)
Abstract Hepatocellular carcinoma (HCC) is a major health concern worldwide, with limited therapeutic options and poor prognosis. In recent years, immunotherapies such as immune checkpoint inhibitors (ICIs) have made great progress in the systemic tr
Externí odkaz:
https://doaj.org/article/71b3951101c047dbb0dc7a737cd5954a
Autor:
Yan Fu, Keyu Shen, Hao Wang, Shun Wang, Xufeng Wang, Le Zhu, Yan Zheng, Tiantian Zou, Hongfei Ci, Qiongzhu Dong, Lun-Xiu Qin
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-16 (2024)
Abstract Neurotransmitter-initiated signaling pathway were reported to play an important role in regulating the malignant phenotype of tumor cells. Cancer cells could exhibit a “neural addiction” property and build up local nerve networks to achi
Externí odkaz:
https://doaj.org/article/f78aaf069c1a4d48af5794845eee6bbf
Autor:
Xiao-Tian Shen, Sun-Zhe Xie, Xin Zheng, Tian-Tian Zou, Bei-Yuan Hu, Jing Xu, Lu Liu, Yun-Feng Xu, Xu-Feng Wang, Hao Wang, Shun Wang, Le Zhu, Kang-Kang Yu, Wen-Wei Zhu, Lu Lu, Ju-Bo Zhang, Jin-Hong Chen, Qiong-Zhu Dong, Lu-Yu Yang, Lun-Xiu Qin
Publikováno v:
Experimental Hematology & Oncology, Vol 13, Iss 1, Pp 1-18 (2024)
Abstract Background Hepatocellular carcinoma (HCC) is closely associatedwith chronic liver diseases, particularly liver cirrhosis, which has an altered extracellular matrix (ECM) composition. The influence and its mechanism of the cirrhotic-ECM on th
Externí odkaz:
https://doaj.org/article/11f20552fc3944ccb8a7f193cd109f08
Autor:
Yan Zheng, Le Zhu, Zhao-Yu Qin, Yu Guo, Shun Wang, Min Xue, Ke-Yu Shen, Bei-Yuan Hu, Xu-Feng Wang, Chao-Qun Wang, Lun-Xiu Qin, Qiong-Zhu Dong
Publikováno v:
Cell Reports, Vol 42, Iss 7, Pp 112666- (2023)
Summary: Protein lysine crotonylation has been recently identified as a vital posttranslational modification in cellular processes, particularly through the modification of histones. We show that lysine crotonylation is an important modification of t
Externí odkaz:
https://doaj.org/article/20ea196dd601414789280bdba1d989ad
Publikováno v:
Aging and Cancer, Vol 3, Iss 1, Pp 20-43 (2022)
Abstract Cancer metastasis is the leading cause of cancer‐related death. It is a complex, inefficient, and multistep process related to poor prognosis and high mortality of patients. Increasing evidence has shown that metabolic programming is a rec
Externí odkaz:
https://doaj.org/article/021300ff723241c6a5ebf6133f7228c6
Autor:
Jinhong Chen, Zhifei Lin, Lu Liu, Rui Zhang, Yan Geng, Minghao Fan, Wenwei Zhu, Ming Lu, Lu Lu, Huliang Jia, Jubo Zhang, Lun-Xiu Qin
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-15 (2021)
Abstract The immunosuppressive microenvironment plays an important role in tumor progression and immunotherapy responses. Golgi membrane protein 1 (GOLM1) is correlated to hepatocellular carcinoma (HCC) progression and metastasis. However, little is
Externí odkaz:
https://doaj.org/article/655aaff5eb9f4607b3edcf26a5358ed8
Autor:
Yingjie Liu, Peiyuan Zhang, Qiuyao Wu, Houqin Fang, Yuan Wang, Yansen Xiao, Min Cong, Tingting Wang, Yunfei He, Chengxin Ma, Pu Tian, Yajun Liang, Lun-Xiu Qin, Qingcheng Yang, Qifeng Yang, Lujian Liao, Guohong Hu
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Disseminated tumor cells often become dormant before awakening for metastatic growth. Here, the authors report that the lncRNA, NR2F1-AS1, is upregulated in dormant mesenchymal-like breast cancer stem-like cells and promotes dissemination but inhibit
Externí odkaz:
https://doaj.org/article/07e81bee36584122863394784ddcccb2
Autor:
Shun Wang, Yan Zheng, Feng Yang, Le Zhu, Xiao-Qiang Zhu, Zhe-Fang Wang, Xiao-Lin Wu, Cheng-Hui Zhou, Jia-Yan Yan, Bei-Yuan Hu, Bo Kong, De-Liang Fu, Christiane Bruns, Yue Zhao, Lun-Xiu Qin, Qiong-Zhu Dong
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-23 (2021)
Abstract Pancreatic cancer is an increasingly common cause of cancer mortality with a tight correspondence between disease mortality and incidence. Furthermore, it is usually diagnosed at an advanced stage with a very dismal prognosis. Due to the hig
Externí odkaz:
https://doaj.org/article/845ae541dfb74cc49141785ab1aeb2ab
Autor:
Le Zhu, Hao-Ting Sun, Shun Wang, Sheng-Lin Huang, Yan Zheng, Chao-Qun Wang, Bei-Yuan Hu, Wei Qin, Tian-Tian Zou, Yan Fu, Xiao-Tian Shen, Wen-Wei Zhu, Yan Geng, Lu Lu, Hu-liang Jia, Lun-Xiu Qin, Qiong-Zhu Dong
Publikováno v:
Journal of Hematology & Oncology, Vol 13, Iss 1, Pp 1-24 (2020)
Abstract Exosomes are a subset of extracellular vesicles that carry specific combinations of proteins, nucleic acids, metabolites, and lipids. Mounting evidence suggests that exosomes participate in intercellular communication and act as important mo
Externí odkaz:
https://doaj.org/article/10abffa0188540d2943213fd26a615bc