Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Lun, Suo"'
Autor:
Qin Xie, Haibo Wu, Hui Long, Caiwen Xiao, Jiaxin Qiu, Weina Yu, Xueyi Jiang, Junbo Liu, Shuo Zhang, Qifeng Lyu, Lun Suo, Yanping Kuang
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 35, Iss 2, Pp 102170- (2024)
Efficient germline mtDNA editing is required to construct disease-related animal models and future gene therapy. Recently, the DddA-derived cytosine base editors (DdCBEs) have made mitochondrial genome (mtDNA) precise editing possible. However, there
Externí odkaz:
https://doaj.org/article/77b24cc2b5a04d098032ecbeb9941d38
Autor:
Jiaxin Qiu, Haibo Wu, Qin Xie, Yuxiao Zhou, Yining Gao, Junbo Liu, Xueyi Jiang, Lun Suo, Yanping Kuang
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
Introduction: Mitochondrial diseases caused by mtDNA have no effective cures. Recently developed DddA-derived cytosine base editors (DdCBEs) have potential therapeutic implications in rescuing the mtDNA mutations. However, the performance of DdCBEs r
Externí odkaz:
https://doaj.org/article/23daffcfb05e4ec8923ccdd1628971da
Autor:
Hui Long, Weina Yu, Sha Yu, Mingru Yin, Ling Wu, Qiuju Chen, Renfei Cai, Lun Suo, Li wang, Qifeng Lyu, Yanping Kuang
Publikováno v:
Journal of Advanced Research, Vol 33, Iss , Pp 189-199 (2021)
Introduction: As an effective inhibitor of premature ovulation, progestin was introduced to a novel ovarian stimulation regimen for infertility treatment. However, the local action of progestin on the ovary and its effect on clinical outcomes have no
Externí odkaz:
https://doaj.org/article/0f25a268d6ca45e1afd5c19ac868c8eb
Publikováno v:
eLife, Vol 7 (2018)
Diverse clustered protocadherins are thought to function in neurite morphogenesis and neuronal connectivity in the brain. Here, we report that the protocadherin alpha (Pcdha) gene cluster regulates neuronal migration during cortical development and c
Externí odkaz:
https://doaj.org/article/6af6f35a783b4501a25ba33f9c4a27f5
Autor:
Qiang Wu, Jingwei Li, Donghong Cui, Yanping Kuang, Lun Suo, Jin Zheng, Liling Jia, Yuxiao Zhou, Xuehong Zhang
Publikováno v:
Journal of Molecular Cell Biology
Clustered protocadherins (Pcdhs) are a large family of cadherin-like cell adhesion proteins that are central for neurite self-avoidance and neuronal connectivity in the brain. Their downstream nonreceptor tyrosine kinase Pyk2 (proline-rich tyrosine k
Publikováno v:
Journal of Cellular Physiology. 236:1043-1053
Ptk2b has been found playing critical roles in oocyte maturation and subsequent fertilization in vitro. But what is the exact in vivo function in reproduction still elusive. Here, by constructing Ptk2b mutant mice, we found Ptk2b was not essential fo
Autor:
Fu, Xiang-Wei, Wu, Guo-Quan, Li, Jun-Jie, Hou, Yun-Peng, Zhou, Guang-Bin, Lun-Suo, Wang, Yan-Ping, Zhu, Shi-En
Publikováno v:
In Theriogenology 2011 75(2):268-275
Autor:
Zheng Yan, Hongxing Liang, Li Deng, Hui Long, Hong Chen, Weiran Chai, Lun Suo, Chen Xu, Yanping Kuang, Lingqian Wu, Shengsheng Lu, Qifeng Lyu
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0145172 (2015)
Increased risk of monozygotic twinning (MZT) has been shown to be associated with assisted reproduction techniques, particularly blastocyst culture. Interestingly, inner cell mass (ICM) splitting in human '8'-shaped hatching blastocysts that resulted
Externí odkaz:
https://doaj.org/article/1c08765bef1d4d04a1964ac832d2a915
Publikováno v:
Human Reproduction.
STUDY QUESTION Does trophectoderm (TE) quality affect birthweight after single frozen-thawed blastocyst transfer? SUMMARY ANSWER Transfer of single blastocyst with advanced TE quality was associated with higher birthweight and increased risk of a lar
Publikováno v:
Reproductive biomedicine online. 41(2)