Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Luminita H Pojoga"'
Autor:
Andrea V Haas, Paul N Hopkins, Nancy J Brown, Luminita H Pojoga, Jonathan S Williams, Gail K Adler, Gordon H Williams
Publikováno v:
Endocrine Connections, Vol 8, Iss 6, Pp 634-640 (2019)
There are conflicting data on whether variations of physiologic cortisol levels associated with cardiovascular risk. We hypothesize that prior discordant findings are related to problems associated with varying sample size, techniques for assessing c
Externí odkaz:
https://doaj.org/article/87bc0b6894e74183acdc85cbfd2b1d85
Autor:
Isis Akemi Katayama, Yuefei Huang, Amanda E. Garza, Danielle L. Brooks, Jonathan S. Williams, Mariana M. Nascimento, Joel C. Heimann, Luminita H. Pojoga
Publikováno v:
Experimental Gerontology, Vol 173, Iss , Pp 112114- (2023)
Background: Dietary sodium is a well-known risk factor for cardiovascular and renal disease; however, direct evidence of the longitudinal changes that occur with aging, and the influence of dietary sodium on the age-associated alterations are scarce.
Externí odkaz:
https://doaj.org/article/29ed570a00834436b50e4c4d49da4fce
Autor:
Mahyar Heydarpour, Wasita W. Parksook, Paul N. Hopkins, Luminita H. Pojoga, Gordon H. Williams, Jonathan S. Williams
Publikováno v:
Journal of Hypertension. 41:723-732
Autor:
Wasita W Parksook, Mahyar Heydarpour, Shadi K Gholami, James M Luther, Paul N Hopkins, Luminita H Pojoga, Jonathan S Williams
Publikováno v:
J Clin Endocrinol Metab
Context Salt sensitivity of blood pressure (SSBP) is associated with increased cardiovascular risk, especially in individuals of African descent, although the underlying mechanisms remain obscure. Lysine-specific demethylase 1 (LSD1) is a salt-sensit
Autor:
Yi Jun Desmond Tan, Danielle L Brooks, Kelly Yin Han Wong, Yuefei Huang, Jose R Romero, Jonathan S Williams, Luminita H Pojoga
Publikováno v:
J Endocrinol
Biologic sex influences the development of cardiovascular disease and modifies aldosterone (ALDO) and blood pressure (BP) phenotypes: females secrete more ALDO, and their adrenal glomerulosa cell is more sensitive to stimulation. Lysine-specific deme
Autor:
Shadi K Gholami, Sanjay Ranjit, Fatty Fazzila Abidin, Elijah Trefts, Siti khairani Mohd Hafiz Ngoo, Amanda Garza, Luminita H Pojoga
Publikováno v:
Hypertension. 79
In humans, caveolin-1 (cav-1) gene polymorphisms confer a metabolic syndrome (MetS) phenotype and higher aldosterone (Aldo) levels. Further, global cav-1 knock out (KO) mice recapitulate the MetS phenotype, with both cardiovascular (CV) and metabolic
Autor:
Tsuyoshi Homma, Mika Homma, Yuefei Huang, Korapat Mayurasakorn, Nurul Mahamad Rodi, Anis Amalina Abdul Hamid, Shelley Hurwitz, Tham Yao, Gail K. Adler, Luminita H. Pojoga, Gordon H. Williams, Jose R. Romero
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 6, Iss 10 (2017)
BackgroundWe hypothesized that caloric restriction (CR) and salt restriction (ResS) would have similar effects on reducing cardiovascular risk markers and that combining CR and ResS would be synergistic in modulating these markers. Methods and Result
Externí odkaz:
https://doaj.org/article/afce01e53cac434ab95872072109b9e7
Autor:
Jiayan Huang, Ezgi Caliskan Guzelce, Shadi K. Gholami, Kara L. Gawelek, Richard N. Mitchell, Luminita H. Pojoga, Jose R. Romero, Gordon H. Williams, Gail K. Adler
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 7; Pages: 6500
Kidney injury molecule-1 (KIM-1) is a biomarker of renal injury and a predictor of cardiovascular disease. Aldosterone, via activation of the mineralocorticoid receptor, is linked to cardiac and renal injury. However, the impact of mineralocorticoid
Autor:
Rene Baudrand, Nidhi Gupta, Amanda E. Garza, Anand Vaidya, Jane A. Leopold, Paul N. Hopkins, Xavier Jeunemaitre, Claudio Ferri, Jose R. Romero, Jonathan Williams, Joseph Loscalzo, Gail K. Adler, Gordon H. Williams, Luminita H. Pojoga
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 5, Iss 10 (2016)
BackgroundOveractivation of the aldosterone and mineralocorticoid receptor (MR) pathway is associated with hyperglycemia and dyslipidemia. Caveolin 1 (cav‐1) is involved in glucose/lipid homeostasis and may modulate MR signaling. We investigated th
Externí odkaz:
https://doaj.org/article/a7ed1ec70b2b4a6b8a2e50760751ff45
Autor:
Burhanuddin Moize, Elijah Trefts, Tham M. Yao, Rene Baudrand, Sanjay Ranjit, Gail K. Adler, Thitinan Treesaranuwattana, Isis Katayama Rangel, Luminita H. Pojoga, Amanda E Garza, Jose R. Romero, Gordon H. Williams, Danielle L Brooks
Publikováno v:
The Journal of Endocrinology
Aldosterone modulates the activity of both epithelial (specifically renal) and non-epithelial cells. Binding to the mineralocorticoid receptor (MR), activates two pathways: the classical genomic and the rapidly activated non-genomic that is substanti