Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Lumelle A. Schneeweis"'
Autor:
Juhi Juneja, Zhou Dai, Daniel Cohen, Lumelle A. Schneeweis, Ruchira Dasgupta, Frank Marsilio, Paul E. Morin
Publikováno v:
BioTechniques. 69(3)
Advances in in vitro display and protein engineering yield therapeutics with affinities in the picomolar range. The Gyrolab® microfluidics platform uses the kinetic exclusion assay principle to measure subnanomolar solution affinities. This work des
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fba2d682eaaf35583a7bc792515be11c
https://pubmed.ncbi.nlm.nih.gov/32672060
https://pubmed.ncbi.nlm.nih.gov/32672060
Autor:
Brenda Stevens, Derek Bond, Hui Wei, Ty M. Brender, Susan H. Julien, Michael L. Gross, Jena Feiner, Johanna Harshman, Richard Y.-C. Huang, Guodong Chen, Nels Hamacher, Luciano Mueller, Lumelle A. Schneeweis, Preeti Sejwal, Jing Li, Stanley R. Krystek, Kristina Moore, Adrienne A. Tymiak, Daniel Cohen, Zheng Lin, Paul O. Sheppard, Claire Noriega
Publikováno v:
Analytical Chemistry. 89:2250-2258
Epitope mapping the specific residues of an antibody/antigen interaction can be used to support mechanistic interpretation, antibody optimization, and epitope novelty assessment. Thus, there is a strong need for mapping methods, particularly integrat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9114ca37113e0a61837a1b73a850d46
https://doi.org/10.1021/acs.analchem.6b03058
https://doi.org/10.1021/acs.analchem.6b03058
Autor:
Michael L. Doyle, Steven Sheriff, Lin Cheng, Melissa Murdock, Wei Yong, Eric J. Lawrence, Vidhyashankar Ramamurthy, Aaron P. Yamniuk, Martin J. Corbett, Lumelle A. Schneeweis
Publikováno v:
Acta Crystallographica Section F Structural Biology Communications. 71:1273-1281
The structure of death receptor 4 (DR4) in complex with TNF-related apoptosis-inducing ligand (TRAIL) has been determined at 3 Å resolution and compared with those of previously determined DR5–TRAIL complexes. Consistent with the high sequence sim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::349f6c6bf63a557ead74d2028c0cfb50
https://doi.org/10.1107/s2053230x15016416
https://doi.org/10.1107/s2053230x15016416
Autor:
Lumelle A. Schneeweis, Steven G. Nadler, Danya Liu, Dawn K. Stetsko, Scott M. Krummey, Maylene E. Wagener, I. Raul Badell, Mandy L. Ford, Suzanne J. Suchard
Publikováno v:
The Journal of Experimental Medicine
Blockade of CD28 signals results in the up-regulation of 2B4 on primary CD8+ effectors and plays a critical role in controlling antigen-specific CD8+ T cell responses.
Mounting evidence in models of both autoimmunity and chronic viral infection
Mounting evidence in models of both autoimmunity and chronic viral infection
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3a14d5044a06fe97f4aa2c78378f4c0
https://doi.org/10.1084/jem.20130902
https://doi.org/10.1084/jem.20130902
Publikováno v:
Microscopy and Microanalysis. 24:1402-1403
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::307799e009f5cba73f575b4784fd59a5
https://doi.org/10.1017/s1431927618007493
https://doi.org/10.1017/s1431927618007493
Functional Dissection of Osteoprotegerin and Its Interaction with Receptor Activator of NF-κB Ligand
Publikováno v:
Journal of Biological Chemistry. 280:41155-41164
The receptor activator of NF-kappaB (RANK) belongs to the neuregulin/tumor necrosis factor (TNF) receptor superfamily and is activated by RANK ligand (RANK-L), a homotrimeric, TNF-like cytokine. RANK is present on the surface of osteoclast cell precu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc5142e6f2fa59f98907c32b065161b8
https://doi.org/10.1074/jbc.m506366200
https://doi.org/10.1074/jbc.m506366200
Autor:
Michael L. Doyle, Aaron P. Yamniuk, Joseph Yanchunas, Zheng Lin, Lumelle A. Schneeweis, Paul E. Morin, James William Bryson, Virginie Lafont
Publikováno v:
Biophysical Methods for Biotherapeutics: Discovery and Development Applications
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::81a36e916d371b22bc51043e3d0e8ce1
https://doi.org/10.1002/9781118354698.ch1
https://doi.org/10.1002/9781118354698.ch1
Autor:
Madhusmita Mitra, Lumelle A. Schneeweis, Sandeep Burma, Matthew Portnoy, B. Franklin Pugh, Amy J. Jackson-Fisher, Robert A. Coleman, Carmelata Chitikila
Publikováno v:
Biochemistry. 38:11340-11348
A kinetic analysis of dimer dissociation, TATA DNA binding, and thermal inactivation of the yeast Saccharomyces cerevisiae and human TATA binding proteins (TBP) was conducted. We find that yeast TBP dimers, like human TBP dimers, are slow to dissocia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::265a5ec1ee0908c35e3a3f9b1e26dd73
https://doi.org/10.1021/bi990911p
https://doi.org/10.1021/bi990911p
Autor:
Catherine A. Fleener, Dawn K. Stetsko, Patricia M. Davis, James K. Tamura, Steven G. Nadler, Haiqing Wang, James William Bryson, Ruth Brosius, Plummer Christopher, Steven Grant, Theodora W. Salcedo, Olga Ignatovich, Lumelle A. Schneeweis, Suzanne J. Suchard, Selena Kansal, Zheng Yang
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 191(9)
Targeting the CD28-CD80/86 pathway with an anti-CD28 antagonist is a promising alternative to current therapies for autoimmunity. However, attempts at generating conventional anti-CD28 mAbs lacking stimulatory activity has been challenging. In this s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f089ba47d75e4524dcc3f204fe5c4249
https://pubmed.ncbi.nlm.nih.gov/24081989
https://pubmed.ncbi.nlm.nih.gov/24081989
Autor:
Parminder Kaur, Alexander Fuhrmann, Stuart Lindsay, Lei Xie, Ralph Abraham, Robert Ros, Michael J. Grace, Ryman Navoa, Christopher R. Yonan, Linda Obenauer Kutner, Lumelle A. Schneeweis, Qiang-Fu, Kirby Steger
Force spectroscopy and recognition imaging are important techniques for characterizing and mapping molecular interactions. In both cases, an antibody is pulled away from its target in times that are much less than the normal residence time of the ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47a73f3dd8b48d44db611c38452e1083
https://europepmc.org/articles/PMC3010837/
https://europepmc.org/articles/PMC3010837/