7- N -Substituted-3-oxadiazole Quinolones with Potent Antimalarial Activity Target the Cytochrome bc 1 Complex.

Autor: Nguyen W; The Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Australia.; Department of Medical Biology, The University of Melbourne, Parkville 3010, Australia., Dans MG; The Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Australia.; Department of Medical Biology, The University of Melbourne, Parkville 3010, Australia., Currie I; The Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Australia.; Department of Medical Biology, The University of Melbourne, Parkville 3010, Australia., Awalt JK; The Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Australia.; Department of Medical Biology, The University of Melbourne, Parkville 3010, Australia., Bailey BL; The Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Australia.; Department of Medical Biology, The University of Melbourne, Parkville 3010, Australia., Lumb C; The Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Australia., Ngo A; The Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Australia., Favuzza P; The Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Australia.; Department of Medical Biology, The University of Melbourne, Parkville 3010, Australia., Palandri J; The Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Australia.; Department of Medical Biology, The University of Melbourne, Parkville 3010, Australia., Ramesh S; Research School of Biology, The Australian National University, Canberra 2600, Australia., Penington J; The Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Australia.; Department of Medical Biology, The University of Melbourne, Parkville 3010, Australia., Jarman KE; The Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Australia.; Department of Medical Biology, The University of Melbourne, Parkville 3010, Australia., Mukherjee P; TCG Lifesciences, Kolkata, West Bengal 700091, India., Chakraborty A; TCG Lifesciences, Kolkata, West Bengal 700091, India., Maier AG; Research School of Biology, The Australian National University, Canberra 2600, Australia., van Dooren GG; Research School of Biology, The Australian National University, Canberra 2600, Australia., Papenfuss T; The Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Australia.; Department of Medical Biology, The University of Melbourne, Parkville 3010, Australia., Wittlin S; Swiss Tropical and Public Health Institute, Kreuzstrasse 2, 4123 Allschwil, Switzerland.; University of Basel, 4003 Basel, Switzerland., Churchyard A; Department of Life Sciences, Imperial College London, South Kensington, SW7 2AZ U.K., Baum J; Department of Life Sciences, Imperial College London, South Kensington, SW7 2AZ U.K.; School of Biomedical Sciences, University of New South Wales, Sydney 2031, Australia., Winzeler EA; School of Medicine, University of California San Diego, 9500 Gilman Drive 0760, La Jolla, California 92093, United States., Baud D; Medicines for Malaria Venture, Geneva 1215, Switzerland., Brand S; Medicines for Malaria Venture, Geneva 1215, Switzerland., Jackson PF; Global Public Health, Janssen R&D LLC, La Jolla, California 92121, United States., Cowman AF; The Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Australia.; Department of Medical Biology, The University of Melbourne, Parkville 3010, Australia., Sleebs BE; The Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Australia.; Department of Medical Biology, The University of Melbourne, Parkville 3010, Australia.

Publikováno v: ACS infectious diseases [ACS Infect Dis] 2023 Mar 10; Vol. 9 (3), pp. 668-691. Date of Electronic Publication: 2023 Feb 28.

The effect of substance P and its common in vivo-formed metabolites on MRGPRX2 and human mast cell activation.

Autor: Hsin L; Department of Biochemistry and Pharmacology, The University of Melbourne, Parkville, Victoria, Australia., Fernandopulle NA; Department of Biochemistry and Pharmacology, The University of Melbourne, Parkville, Victoria, Australia., Ding J; Department of Biochemistry and Pharmacology, The University of Melbourne, Parkville, Victoria, Australia., Lumb C; Drug Discovery Biology Theme, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia., Veldhuis N; Drug Discovery Biology Theme, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia., Karas JA; School of Chemistry, The University of Melbourne, Parkville, Victoria, Australia., Northfield SE; Department of Biochemistry and Pharmacology, The University of Melbourne, Parkville, Victoria, Australia., Mackay GA; Department of Biochemistry and Pharmacology, The University of Melbourne, Parkville, Victoria, Australia.

Publikováno v: Pharmacology research & perspectives [Pharmacol Res Perspect] 2022 Aug; Vol. 10 (4), pp. e00990.

'What research was carried out on this vaginal mesh?' Health‐related concerns in women following mesh‐augmented prolapse surgery: a thematic analysis.

Autor: Izett‐Kay, ML, Lumb, C, Cartwright, R, Kupelian, AS, Cutner, AS, Jackson, S, Price, N, Vashisht, A

Publikováno v: BJOG: An International Journal of Obstetrics & Gynaecology; Jan2021, Vol. 128 Issue 1, p131-139, 9p

Identification of a Potential PGK1 Inhibitor with the Suppression of Breast Cancer Cells Using Virtual Screening and Molecular Docking.

Autor: Chen, Xianghui^1,2 (AUTHOR), Zuo, Zanwen³ (AUTHOR), Li, Xianbin⁴ (AUTHOR), Li, Qizhang³ (AUTHOR) liqzh5@mail2.sysu.edu.cn, Zhang, Lei^1,2,3,5 (AUTHOR) liqzh5@mail2.sysu.edu.cn

Publikováno v: Pharmaceuticals (14248247). Dec2024, Vol. 17 Issue 12, p1636. 19p.

Genetic characterization of candidate ecdysteroid kinases in Drosophila melanogaster.

Autor: Scanlan, Jack L¹ (AUTHOR), Robin, Charles¹ (AUTHOR) crobin@unimelb.edu.au

Publikováno v: G3: Genes | Genomes | Genetics. Nov2024, Vol. 14 Issue 11, p1-17. 17p.