Zobrazeno 1 - 5 of 5 pro vyhledávání: '"Lulufer Tamer Gumus"'
1
Antioxidant and Neuroprotective Effects of L-arginine Administration After Traumatic Brain Injury and Hemorrhagic Shock in Rats
Autor: Goksu Bozdereli Berikol, Gurkan Berikol, Cuneyt Ayrik, Ataman Kose, Seyran Bozkurt Babus, Lulufer Tamer Gumus, Rabia Bozdogan Arpaci, Ahmet Dag, Erhan Ayan, Aysegul Gorur
Publikováno v: Turkish neurosurgery.
The aim of the current study was to investigate the effect of fluid resuscitation and L-arginine administration on oxidant status markers, blood gases, lactate and apoptosis in the brain tissue of a rat model of TBI with hemorrhagic shock.A total of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df843b2c0712155dc658e76f62502211
https://pubmed.ncbi.nlm.nih.gov/35929035
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2
Modulation of oxidative–nitrosative stress and inflammatory response by rapamycin in target and distant organs in rats exposed to hindlimb ischemia–reperfusion: the role of mammalian target of rapamycin
Autor: Seyhan Sahan-Firat, Senay Balci, Özden Vezir, Lulufer Tamer-Gumus, Bahar Tunctan, Meryem Temiz-Resitoglu, Kafait U. Malik, Zumrut Kocak, Demet Sinem Guden, Nehir Sucu
Publikováno v: Canadian Journal of Physiology and Pharmacology. 97:1193-1203
Mammalian target of rapamycin (mTOR) has been recognized with potential immunomodulatory properties playing an important role in various physiopathological processes including ischemia–reperfusion (I/R) injury. I/R injury stimulate reactive oxygen
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac436769f8ee2eab3293a06a07ba755e
https://doi.org/10.1139/cjpp-2019-0394
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3
The role of Syk/IĸB-α/NF-ĸB pathway activation in the reversal effect of BAY 61-3606, a selective Syk inhibitor, on hypotension and inflammation in a rat model of zymosan-induced non-septic shock
Autor: Meltem Kacan, Lulufer Tamer-Gumus, Demet Sinem Guden, Bahar Tunctan, Seyhan Sahan-Firat, Meryem Temiz-Resitoglu, Ayse Nihal Sari, Belma Korkmaz, Kafait U. Malik, Hatice Yildirim-Yaroglu, Cuneyt Kemal Buharalioglu, Demet Unsal
Publikováno v: Clinical and experimental pharmacologyphysiology. 45(2)
Summary Spleen tyrosine kinase (Syk), a non-receptor tyrosine kinase, plays an important role in allergic diseases and inflammation. Syk triggers several intracellular signalling cascades including Toll-like receptor signalling to activate inflammato
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fffa1fdc818e71356866c60d913ab21a
https://pubmed.ncbi.nlm.nih.gov/28949404
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4
Activation of mTOR/IκB-α/NF-κB pathway contributes to LPS-induced hypotension and inflammation in rats
Autor: Meryem Temiz-Resitoglu, Demet Sinem Guden, Seyhan Sahan-Firat, Lulufer Tamer-Gumus, Aysegul Gorur, Ayse Nihal Sari, Kafait U. Malik, Sefika Pinar Kucukkavruk, Cuneyt Kemal Buharalioglu, Pelin Cecen, Bahar Tunctan
Publikováno v: European journal of pharmacology. 802
Mammalian target of rapamycin (mTOR), a serine/threonine kinase plays an important role in various pathophysiological processes including cancer, metabolic diseases, and inflammation. Although mTOR participates in Toll-like receptor 4 signalling in d
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::416257cfda939d0f9c502739a6b72768
https://pubmed.ncbi.nlm.nih.gov/28228357
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