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Akademický článek

Whole-genome sequencing of glioblastoma reveals enrichment of non-coding constraint mutations in known and novel genes

Autor: Sharadha Sakthikumar, Ananya Roy, Lulu Haseeb, Mats E. Pettersson, Elisabeth Sundström, Voichita D. Marinescu, Kerstin Lindblad-Toh, Karin Forsberg-Nilsson

Publikováno v: Genome Biology, Vol 21, Iss 1, Pp 1-22 (2020)

Abstract Background Glioblastoma (GBM) has one of the worst 5-year survival rates of all cancers. While genomic studies of the disease have been performed, alterations in the non-coding regulatory regions of GBM have largely remained unexplored. We a

Externí odkaz: https://doaj.org/article/bace325326104f708a9d8e09bc2fb81c

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Supplementary Figure S1 from Inhibition of Heparanase in Pediatric Brain Tumor Cells Attenuates their Proliferation, Invasive Capacity, and In Vivo Tumor Growth

Autor: Karin Forsberg-Nilsson, Israel Vlodavsky, Uri Barash, Edward Hammond, Keith Dredge, Tommie Olofsson, Di Yu, Lulu Haseeb, Soumi Kundu, Argyris Spyrou

Combinatorial effect of PG545 and conditioned medium (CM) on cell viability, and examination of apoptosis after downregulation of HPSE

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2eb2d25db09561c4bb86d75386ae1ba9
https://doi.org/10.1158/1535-7163.22507746

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Supplementary Figure Legends from Inhibition of Heparanase in Pediatric Brain Tumor Cells Attenuates their Proliferation, Invasive Capacity, and In Vivo Tumor Growth

Autor: Karin Forsberg-Nilsson, Israel Vlodavsky, Uri Barash, Edward Hammond, Keith Dredge, Tommie Olofsson, Di Yu, Lulu Haseeb, Soumi Kundu, Argyris Spyrou

Supplementary Figure Legends

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28e704d66517e983fd5a0f9d9c708e88
https://doi.org/10.1158/1535-7163.22507749

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Data from Inhibition of Heparanase in Pediatric Brain Tumor Cells Attenuates their Proliferation, Invasive Capacity, and In Vivo Tumor Growth

Autor: Karin Forsberg-Nilsson, Israel Vlodavsky, Uri Barash, Edward Hammond, Keith Dredge, Tommie Olofsson, Di Yu, Lulu Haseeb, Soumi Kundu, Argyris Spyrou

Curative therapy for medulloblastoma and other pediatric embryonal brain tumors has improved, but the outcome still remains poor and current treatment causes long-term complications. Malignant brain tumors infiltrate the healthy brain tissue and, thu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53805dcf0956a957656703bf08a20cd5
https://doi.org/10.1158/1535-7163.c.6538773.v1

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