Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Lulin Nie"'
Autor:
Lulin Nie, Kaiwu He, Chaoming Qiu, Qing Li, Bocheng Xiong, Chuanyue Gao, Xiufen Zhang, Mei Jing, Wei Wu, Jianjun Liu, Gaoxiao Zhang, Zaijun Zhang, Xifei Yang, Yewei Sun, Yuqiang Wang
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 173, Iss , Pp 116415- (2024)
Tetramethylpyrazine nitrone (TBN), a novel derivative of tetramethylpyrazine (TMP) designed and synthesized by our group, possesses multi-functional mechanisms of action and displays broad protective effects in vitro and in animal models of age-relat
Externí odkaz:
https://doaj.org/article/9c28d0d3e49e4ca0ace1f7b19d2bea3f
Publikováno v:
Experimental Gerontology, Vol 187, Iss , Pp 112375- (2024)
Stress response is a fundamental mechanism for cell survival, providing protection under unfavorable conditions. Mitochondrial stress, in particular, can trigger mitophagy, a process that restores cellular health. Exhaustive exercise (EE) is a form o
Externí odkaz:
https://doaj.org/article/7b4bb9f19ba34cbb8c58507e56ddf758
Autor:
Kaiwu He, Lulin Nie, Tahir Ali, Zizhen Liu, Weifen Li, Ruyan Gao, Zena Zhang, Jianjun Liu, Zhongliang Dai, Yongmei Xie, Zaijun Zhang, Gongping Liu, Ming Dong, Zhi-Jian Yu, Shupeng Li, Xifei Yang
Publikováno v:
Immunity & Ageing, Vol 20, Iss 1, Pp 1-13 (2023)
Abstract Background A wide spectrum of changes occurs in the brain with age, from molecular to morphological aspects, and inflammation accompanied by mitochondria dysfunction is one of the significant factors associated with age. Adiponectin (APN), a
Externí odkaz:
https://doaj.org/article/bef7bd9f1a1e4a68bb8431eaa56116a4
Autor:
Jiacheng Zhong, Xiaohu Ren, Wei Liu, Shuqi Wang, Yuan Lv, Lulin Nie, Rongying Lin, Xiaoping Tian, Xifei Yang, Feiqi Zhu, Jianjun Liu
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
Alzheimer’s disease (AD), the predominant cause of late-life dementia, has a multifactorial etiology. Since there are few therapeutic options for symptomatic AD, research is increasingly focused on the identification of pre-symptomatic biomarkers.
Externí odkaz:
https://doaj.org/article/e7e8de703c6d46cfbd15e0ba4a5d3f42
Autor:
Li Liu, Xian Wang, Li Zhou, Jing Yuan, Jianjun Liu, Weihong Chen, Lulin Nie, Zhiwei Guo, Yi Luo, Weimin Liu, Feiqi Zhu, Jiafei Zhang, Tian Li, Erwei Gao, Kaiwu He, Yidan Huang, Chunjie Yuan, Qingqing Zhu, Fang Ye, Xingchen Yu
Publikováno v:
BMJ Open, Vol 10, Iss 6 (2020)
Purpose The Shenzhen ageing-related disorder cohort was designed to detect the associations of lifestyle, environmental and genetic factors with major ageing-related disorders, especially neurological and mental disorders.Participants The cohort was
Externí odkaz:
https://doaj.org/article/2f9c5535763b4794bd434e13fc4dc2a1
Autor:
Shupeng Li, Kaiwu He, Fengzhu Xie, Li Zhou, Lulin Nie, Liangyu Zou, Xifei Yang, Shifeng Xiao, Jia Xu, Chen Yang, Kaiqin Zhang, Jianjun Liu
Publikováno v:
Aging (Albany NY)
Alzheimer’s disease (AD) is the most common age-related neurodegenerative disease threatening the health of the elderly, but the available therapeutic and preventive drugs remain suboptimal. Loganin, an iridoid glycoside extracted from Cornus offic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d468eed0e4e29d2789e6df481d54a15
https://doi.org/10.18632/aging.203646
https://doi.org/10.18632/aging.203646
Autor:
Kaiwu He, Lulin Nie, Tahir Ali, Zizhen Liu, Weifen Li, Ruyan Gao, Jianjun Liu, Zhongliang Dai, Yongmei Xie, Zaijun Zhang, Gongping Liu, Ming Dong, Zhi-Jian Yu, Shupeng Li, Xifei Yang
A wide spectrum of changes occur in the brain with age, from molecular to morphological aspects, and inflammation accompanied by mitochondria dysfunctions is one of the significant processes and factors associated with age. Adiponectin (APN), an adip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d170c9db640f0690bb14940466512879
https://doi.org/10.21203/rs.3.rs-1549257/v1
https://doi.org/10.21203/rs.3.rs-1549257/v1
Autor:
Shupeng Li, Lulin Nie, Zhongliang Dai, Xifei Yang, Kaiwu He, Kaiqin Zhang, Jianjun Liu, Dingxin Long, Jia Xu
Publikováno v:
Toxicology and industrial health. 37(12)
Manganese (Mn) is required for normal brain development and function. Excess Mn may trigger a parkinsonian movement disorder but the underlying mechanisms are incompletely understood. We explored changes in the brain proteomic profile and movement be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be1acf8ad7d86650b7ca7cd933769e3f
https://pubmed.ncbi.nlm.nih.gov/34706592
https://pubmed.ncbi.nlm.nih.gov/34706592
Autor:
Tahir Ali, Weifen Li, Jia Xu, Shupeng Li, Zhi-Jian Yu, Lulin Nie, Kaiwu He, Jianjun Liu, Xiao Chen, Shujin Wang, Xifei Yang, Kaiqin Zhang, Zizhen Liu
Publikováno v:
Aging Cell
Adiponectin (APN) deficiency has also been associated with Alzheimer‐like pathologies. Recent studies have illuminated the importance of APN signaling in reducing Aβ accumulation, and the Aβ elimination mechanism remains rudimentary. Therefore, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5475569df58dca03e5779d472f6a5ea
https://pubmed.ncbi.nlm.nih.gov/34775673
https://pubmed.ncbi.nlm.nih.gov/34775673
Autor:
Chao Yang, Lulin Nie, Kaiqin Zhang, Chang-E Zhang, Kaiwu He, Jianjun Liu, Ding Dan, Jia Xu, Xifei Yang
Publikováno v:
Oxidative Medicine and Cellular Longevity, Vol 2021 (2021)
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity
Depression is one of the most common neuropsychiatric disorders. Although the pathogenesis of depression is still unknown, environmental risk factors and genetics are implicated. Copper (Cu), a cofactor of multiple enzymes, is involved in regulating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9c47d65e8d77ad6f2f64b2e001678f4
https://pubmed.ncbi.nlm.nih.gov/33833851
https://pubmed.ncbi.nlm.nih.gov/33833851