Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Lulin Ji"'
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Dedicator of cytokinesis 2 (DOCK2) can activate the downstream small G protein Rac and regulate cytoskeletal reorganization. DOCK2 is essential for critical physiological processes such as migration, activation, proliferation, and effects of immune c
Externí odkaz:
https://doaj.org/article/bc0a55662ed64a94871ecf3bf8defc49
Autor:
Ruobing Zhang, Tiantian Guo, Lulin Ji, Yirui Yin, Shuitu Feng, Weihong Lu, Fei Zhang, Maoshu Zhu, Shugang Liu, Jinhua Jiang, Fanwei Zeng
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Human gastrointestinal cancer (e.g., gastric cancer and colorectal cancer) has been a leading cause of cancer-related deaths worldwide and has imposed a great threat to the public health. Although early-stage gastrointestinal cancer can be effectivel
Externí odkaz:
https://doaj.org/article/75b96a861a2d4677a6ac321594d51c30
Autor:
Michael L. van de Weijer, Krishna Samanta, Nikita Sergejevs, LuLin Jiang, Maria Emilia Dueñas, Tiaan Heunis, Timothy Y. Huang, Randal J. Kaufman, Matthias Trost, Sumana Sanyal, Sally A. Cowley, Pedro Carvalho
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Immune surveillance by cytotoxic T cells eliminates tumor cells and cells infected by intracellular pathogens. This process relies on the presentation of antigenic peptides by Major Histocompatibility Complex class I (MHC-I) at the cell surf
Externí odkaz:
https://doaj.org/article/48a91d8bd1874f4caa6ab396c81c07b0
Autor:
Yirui Yin, Shugang Liu, Shuitu Feng, Fei Zhang, Fanwei Zeng, Ruobing Zhang, Weihong Lu, Lulin Ji, Tiantian Guo, Maoshu Zhu, Jinhua Jiang
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Frontiers in Oncology
Frontiers in Oncology
Human gastrointestinal cancer (e.g., gastric cancer and colorectal cancer) has been a leading cause of cancer-related deaths worldwide and has imposed a great threat to the public health. Although early-stage gastrointestinal cancer can be effectivel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30c0455476dff3c3394ae53fc300ade0
https://www.frontiersin.org/articles/10.3389/fonc.2021.716339/full
https://www.frontiersin.org/articles/10.3389/fonc.2021.716339/full
Publikováno v:
Clin Exp Immunol
Summary Dedicator of cytokinesis 2 (Dock2), an atypical guanine exchange factor, is specifically expressed on immune cells and mediates cell adhesion and migration by activating Rac and regulates actin cytoskeleton remodeling. It plays a crucial role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8eb0d6c6fddf7a023f75ce10e34fe00c
https://pubmed.ncbi.nlm.nih.gov/33662140
https://pubmed.ncbi.nlm.nih.gov/33662140
Autor:
Qiuyang Zheng, Beibei Song, Guilin Li, Fang Cai, Meiling Wu, Yingjun Zhao, LuLin Jiang, Tiantian Guo, Mingyu Shen, Huan Hou, Ying Zhou, Yini Zhao, Anjie Di, Lishan Zhang, Fanwei Zeng, Xiu-Fang Zhang, Hong Luo, Xian Zhang, Hongfeng Zhang, Zhiping Zeng, Timothy Y. Huang, Chen Dong, Hong Qing, Yun Zhang, Qing Zhang, Xu Wang, Yili Wu, Huaxi Xu, Weihong Song, Xin Wang
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 5 (2022)
Down syndrome (DS), or trisomy 21, is one of the critical risk factors for early-onset Alzheimer’s disease (AD), implicating key roles for chromosome 21–encoded genes in the pathogenesis of AD. We previously identified a role for the deubiquitina
Externí odkaz:
https://doaj.org/article/31b1783f35ed41c69b3c8b868c85a09c
Autor:
Bing Zhu, LuLin Jiang, Timothy Huang, Yingjun Zhao, Tongfei Liu, Yongwang Zhong, Xiaoguang Li, Alexandre Campos, Kenneth Pomeroy, Eliezer Masliah, Dongxian Zhang, Huaxi Xu
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Endoplasmic-reticulum associated degradation (ERAD) regulates protein homeostasis. Here the authors identify an ERAD component membralin, and show that it interacts with a member of the γ-secretase complex to regulate β-amyloid (Aβ) pathology and
Externí odkaz:
https://doaj.org/article/0b2b5777bfa844f4855e75bfcbd6c2fd