Zobrazeno 1 - 10
of 139
pro vyhledávání: '"Lulin, Huang"'
Autor:
Wenjing Liu, Shujin Li, Mu Yang, Jie Ma, Lu Liu, Ping Fei, Qianchun Xiang, Lulin Huang, Peiquan Zhao, Zhenglin Yang, Xianjun Zhu
Publikováno v:
eLife, Vol 13 (2024)
Familial exudative vitreoretinopathy (FEVR) is a severe genetic disorder characterized by incomplete vascularization of the peripheral retina and associated symptoms that can lead to vision loss. However, the underlying genetic causes of approximatel
Externí odkaz:
https://doaj.org/article/d74e1bf8c8cd48a5a233414b8dbc8fa7
Autor:
Lulin Huang, Lin Ye, Runze Li, Shanshan Zhang, Chao Qu, Shujin Li, Jie Li, Mu Yang, Biao Wu, Ran Chen, Guo Huang, Bo Gong, Zheng Li, Hongjie Yang, Man Yu, Yi Shi, Changguan Wang, Wei Chen, Zhenglin Yang
Publikováno v:
Genes and Diseases, Vol 10, Iss 6, Pp 2540-2556 (2023)
The retinal pigment epithelium (RPE) and choroid are located behind the human retina and have multiple functions in the human visual system. Knowledge of the RPE and choroid cells and their gene expression profiles are fundamental for understanding r
Externí odkaz:
https://doaj.org/article/72da488b65714fdaaef59752a62d8d34
Autor:
Haixin Wang, Ping Shuai, Yanhui Deng, Jiyun Yang, Yi Shi, Dongyu Li, Tao Yong, Yuping Liu, Lulin Huang
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-18 (2022)
Abstract As a systematic investigation of the correlations between physical examination indicators (PEIs) is lacking, most PEIs are currently independently used for disease warning. This results in the general physical examination having limited diag
Externí odkaz:
https://doaj.org/article/35d82968e9a9480687f72d07558818e5
Autor:
Bo Gong, Lulin Huang, Yongquan He, Wen Xie, Yi Yin, Yi Shi, Jialing Xiao, Ling Zhong, Yi Zhang, Zhilin Jiang, Fang Hao, Yu Zhou, Huan Li, Li Jiang, Xingxiang Yang, Xiangrong Song, Yan Kang, Lin Tuo, Yi Huang, Ping Shuai, Yuping Liu, Fang Zheng, Zhenglin Yang
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 7, Iss 1, Pp 1-7 (2022)
Abstract Critical coronavirus disease 2019 (COVID-19) is associated with high mortality and potential genetic factors have been reported to be involved in the development of critical COVID-19. We performed a genome-wide association study to identify
Externí odkaz:
https://doaj.org/article/876eaf3a65cf4e2b9ea068010a0aba4c
Publikováno v:
Genes and Diseases, Vol 9, Iss 2, Pp 479-493 (2022)
Huntington's disease (HD) is caused by a CAG repeat expansion in the huntingtin (HTT) gene. Knock-in mice carrying a CAG repeat-expanded Htt will develop HD phenotypes. Previous studies suggested dysregulated molecular networks in a CAG length genoty
Externí odkaz:
https://doaj.org/article/0a9a0085fd6c4d0c9d6fe40e331240af
Publikováno v:
Genes and Diseases, Vol 9, Iss 1, Pp 62-79 (2022)
Age-related macular degeneration (AMD) is a complex eye disorder and is the leading cause of incurable blindness worldwide in the elderly. Clinically, AMD initially affects the central area of retina known as the macula and it is classified as early
Externí odkaz:
https://doaj.org/article/60539f0a425a413baf7617915af588ac
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Müller cell is the most abundant glial cell in mammalian retina, supporting the functions of photoreceptors and other retinal neurons via maintaining environmental homeostasis. In response to injury and/or neuronal degeneration, Müller cells underg
Externí odkaz:
https://doaj.org/article/201d12c5d32b408ea0571dce56eabbf0
Autor:
Lulin Huang, Yi Shi, Bo Gong, Li Jiang, Zhixin Zhang, Xiaoqi Liu, Jialiang Yang, Yongquan He, Zhilin Jiang, Ling Zhong, Juan Tang, Chunfang You, Qi Jiang, Bo Long, Tao Zeng, Mei Luo, Fanwei Zeng, Fanxin Zeng, Shuqiang Wang, Xingxiang Yang, Zhenglin Yang
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-12 (2021)
Abstract The 2019 coronavirus disease (COVID-19) outbreak caused by the SARS-CoV-2 virus is an ongoing global health emergency. However, the virus’ pathogenesis remains unclear, and there is no cure for the disease. We investigated the dynamic chan
Externí odkaz:
https://doaj.org/article/611f51caee664fd8891ccef348d8ce17
Autor:
Yi Yin, Yi Zhang, Lelin Sun, Shuqiang Wang, Yong Zeng, Bo Gong, Lulin Huang, Yongquan He, Zhenglin Yang
Publikováno v:
Virologica Sinica (16740769); Apr2024, Vol. 39 Issue 2, p347-350, 4p
Publikováno v:
BMC Medical Genetics, Vol 20, Iss 1, Pp 1-8 (2019)
Abstract Background Focal segmental glomerulosclerosis (FSGS) is still one of the common causes of refractory nephrotic syndrome. Nephrin, encoded by podocyte-specific NPHS1 gene, participated in the pathogenesis of FSGS. The sites of NPHS1 mutations
Externí odkaz:
https://doaj.org/article/65d98bb91a1a4dd8805fd8e7e654f8a5