Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Luke Yongkyu Kwon"'
Publikováno v:
iScience, Vol 27, Iss 5, Pp 109750- (2024)
Summary: HER2 heterogeneity is a challenge for molecular imaging or treating HER2-positive breast cancer (BC). EGFR is coexpressed in some tumors exhibiting HER2 heterogeneity. Bispecific radioimmunoconjugates (bsRICs) that bind HER2 and EGFR were co
Externí odkaz:
https://doaj.org/article/1f6222674072471191626dfa25582a11
Autor:
Kevin Wyszatko, Luis Rafael Silva, Teesha Komal, Luke Yongkyu Kwon, Manuela Ventura, Sheila Singh, John Valliant, Saman Sadeghi
Publikováno v:
Nuclear Medicine and Biology. :S19-S20
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::31123612367b48139b58ce661306ebe6
https://doi.org/10.1016/s0969-8051(22)02137-0
https://doi.org/10.1016/s0969-8051(22)02137-0
Publikováno v:
Molecular Pharmaceutics. 14:492-501
Heterodimerization of EGFR with HER2 coexpressed in breast cancer (BC) promotes tumor growth, and increased EGFR expression is associated with trastuzumab resistance. Our aim was to construct 64Cu-labeled bispecific radioimmunoconjugates (bsRIC) comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60df24e811f42d92b69c44aa65e4fb24
https://doi.org/10.1021/acs.molpharmaceut.6b00963
https://doi.org/10.1021/acs.molpharmaceut.6b00963