Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Luke V. Blakeway"'
Autor:
Hoai-An Nguyen, Anton Y. Peleg, Jiangning Song, Bhavna Antony, Geoffrey I. Webb, Jessica A. Wisniewski, Luke V. Blakeway, Gnei Z. Badoordeen, Ravali Theegala, Helen Zisis, David L. Dowe, Nenad Macesic
Publikováno v:
mSystems, Vol 9, Iss 9 (2024)
ABSTRACT Matrix-assisted laser desorption/ionization–time of flight mass spectrometry (MALDI-TOF MS) is widely used in clinical microbiology laboratories for bacterial identification but its use for detection of antimicrobial resistance (AMR) remai
Externí odkaz:
https://doaj.org/article/7cdd394611be42aa8483358a964f7057
Autor:
Nenad Macesic, Jane Hawkey, Ben Vezina, Jessica A. Wisniewski, Hugh Cottingham, Luke V. Blakeway, Taylor Harshegyi, Katherine Pragastis, Gnei Zweena Badoordeen, Amanda Dennison, Denis W. Spelman, Adam W. J. Jenney, Anton Y. Peleg
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Infections caused by metallo-beta-lactamase-producing organisms (MBLs) are a global health threat. Our understanding of transmission dynamics and how MBLs establish endemicity remains limited. We analysed two decades of bla IMP-4 evolution i
Externí odkaz:
https://doaj.org/article/85869f653dc24df6bcd7067f96605c72
Autor:
Michael J. Loftus, Tracey E.M.W. Young-Sharma, Sue J. Lee, Shitanjni Wati, Gnei Z. Badoordeen, Luke V. Blakeway, Sally M.H. Byers, Allen C. Cheng, Ben S. Cooper, Hugh Cottingham, Adam W.J. Jenney, Jane Hawkey, Nenad Macesic, Ravi Naidu, Amitesh Prasad, Vinita Prasad, Litia Tudravu, Timoci Vakatawa, Elke van Gorp, Jessica A. Wisniewski, Eric Rafai, Anton Y. Peleg, Andrew J. Stewardson
Publikováno v:
Journal of Global Antimicrobial Resistance, Vol 30, Iss , Pp 286-293 (2022)
ABSTRACT: Objectives: There are scant primary clinical data on antimicrobial resistance (AMR) burden from low- and middle-income countries (LMICs). We adapted recent World Health Organization methodology to measure the effect of third-generation ceph
Externí odkaz:
https://doaj.org/article/9e5c3937b73c473fb03a980ad3b100e1
Autor:
Michael J. Loftus, Tracey E.M.W. Young-Sharma, Shitanjni Wati, Gnei Z. Badoordeen, Luke V. Blakeway, Sally M.H. Byers, Allen C. Cheng, Adam W.J. Jenney, Ravi Naidu, Amitesh Prasad, Vinita Prasad, Litia Tudravu, Timoci Vakatawa, Elke van Gorp, Jessica A. Wisniewski, Eric Rafai, Andrew J. Stewardson, Anton Y. Peleg
Publikováno v:
The Lancet Regional Health. Western Pacific, Vol 22, Iss , Pp 100438- (2022)
Summary: Background: Staphylococcus aureus bacteraemia (SAB) is one of the commonest bloodstream infections globally and is associated with a high mortality rate. Most published data comes from temperate, high-income countries. We describe the clinic
Externí odkaz:
https://doaj.org/article/1b047287029a4157b9514c14f9e0c931
Autor:
Luke V. Blakeway, Aimee Tan, Joseph A. Jurcisek, Lauren O. Bakaletz, John M. Atack, Ian R. Peak, Kate L. Seib
Publikováno v:
BMC Microbiology, Vol 19, Iss 1, Pp 1-14 (2019)
Abstract Background Moraxella catarrhalis is a leading cause of otitis media (OM) and chronic obstructive pulmonary disease (COPD). M. catarrhalis contains a Type III DNA adenine methyltransferase (ModM) that is phase-variably expressed (i.e., its ex
Externí odkaz:
https://doaj.org/article/5ec23ad9abc04ad38a899e8299026829
Autor:
Aimee Tan, Luke V Blakeway, Taha, Yuedong Yang, Yaoqi Zhou, John M Atack, Ian R Peak, Kate L Seib
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0234306 (2020)
Moraxella catarrhalis is a human-adapted, opportunistic bacterial pathogen of the respiratory mucosa. Although asymptomatic colonization of the nasopharynx is common, M. catarrhalis can ascend into the middle ear, where it is a prevalent causative ag
Externí odkaz:
https://doaj.org/article/c0027d8ed68a438aa769ee502b44cb26
Autor:
Nenad Macesic, Jane Hawkey, Ben Vezina, Jessica A. Wisniewski, Hugh Cottingham, Luke V. Blakeway, Taylor Harshegyi, Katherine Pragastis, Gnei Zweena Badoordeen, Amanda Dennison, Denis W. Spelman, Adam W.J. Jenney, Anton Y. Peleg
Infections caused by metallo-beta-lactamase-producing organisms (MBLs) are a global health threat. Our understanding of transmission dynamics and how MBLs establish endemicity remains limited. We analysed two decades ofblaIMP-4evolution in a hospital
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2090faa1feb0eaf193a67f90843e050c
https://doi.org/10.1101/2023.03.25.534241
https://doi.org/10.1101/2023.03.25.534241
Autor:
Micaela Mossop, Luca Robinson, Jhih-Hang Jiang, Anton Y. Peleg, Luke V. Blakeway, Nenad Macesic, Audrey Perry, Stephen Bourke, Fatima R. Ulhuq, Tracy Palmer
IntroductionOne third of people with CF in the UK are co-infected by bothStaphylococcus aureusandPseudomonas aeruginosa. Chronic bacterial infection in CF contributes to the gradual destruction of lung tissue, and eventually respiratory failure in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce11cc9b549d7fc68319e88cf2f46bf5
https://doi.org/10.1101/2022.12.20.520977
https://doi.org/10.1101/2022.12.20.520977
Autor:
Ian R. Peak, Lauren O. Bakaletz, Aimee Tan, John M. Atack, Joseph A. Jurcisek, Luke V. Blakeway, Kate L. Seib
Publikováno v:
BMC Microbiology, Vol 19, Iss 1, Pp 1-14 (2019)
BMC Microbiology
BMC Microbiology
Background Moraxella catarrhalis is a leading cause of otitis media (OM) and chronic obstructive pulmonary disease (COPD). M. catarrhalis contains a Type III DNA adenine methyltransferase (ModM) that is phase-variably expressed (i.e., its expression
Autor:
Anthony D. Verderosa, Wing-Sze Li, Makrina Totsika, Kate L. Seib, Tsitsi D. Mubaiwa, Aimee Tan, Luke V. Blakeway
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
Scientific Reports
Scientific Reports
Moraxella catarrhalis is a host-adapted bacterial pathogen that causes otitis media and exacerbations of chronic obstructive pulmonary disease. This study characterises the conserved M. catarrhalis extracellular nuclease, a member of the ββα metal