Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Luke S. Uebelhoer"'
Autor:
Michelle L. Underwood, Byung Park, Luke S. Uebelhoer, Geoffrey Gu, Lynn E. Kunkel, Philip T. Korthuis, Ryan R. Cook, Rafick Pierre Sekaly, Susan Pereira Ribeiro, Christina L. Lancioni
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Despite advances in antiretroviral therapy, chronic immune activation continues to be observed among individuals with well-controlled HIV viral loads, and is associated with non-AIDS defining morbidities among people living with HIV. Alcohol use diso
Externí odkaz:
https://doaj.org/article/7121c15dcf3e4788b335243beb7cdbb4
Autor:
Ruth J. Napier, Ellen J. Lee, Michael P. Davey, Emily E. Vance, João M. Furtado, Paige E. Snow, Kimberly A. Samson, Sydney J. Lashley, Brieanna R. Brown, Reiko Horai, Mary J. Mattapallil, Biying Xu, Michelle C. Callegan, Luke S. Uebelhoer, Christina L. Lancioni, Richard K. Vehe, Bryce A. Binstadt, Justine R. Smith, Rachel R. Caspi, Holly L. Rosenzweig
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
How mutations in the microbial receptor NOD2 induce Blau syndrome in humans and related uveitis is unclear. Here the authors show, using Nod2-deficient mice and experimental uveitis, that Nod2 negatively regulates T cell activation and transcription
Externí odkaz:
https://doaj.org/article/5c09fe5a329b4c398f56c7642549fe79
Autor:
Luke S. Uebelhoer, Agnes Gwela, Bonnie Thiel, Sophie Nalukwago, John Mukisa, Christopher Lwanga, Justine Getonto, Emily Nyatichi, Grace Dena, Alexander Makazi, Shalton Mwaringa, Ezekiel Mupere, James A. Berkley, Christina L. Lancioni
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
Severely ill children in low- and middle-income countries (LMICs) experience high rates of mortality from a broad range of infectious diseases, with the risk of infection-related death compounded by co-existing undernutrition. How undernutrition and
Externí odkaz:
https://doaj.org/article/3ee35c74c50f4083a5f71553c615a3d8
Autor:
Amy J. Schuh, Brian R. Amman, Megan E. B. Jones, Tara K. Sealy, Luke S. Uebelhoer, Jessica R. Spengler, Brock E. Martin, Jo Ann D. Coleman-McCray, Stuart T. Nichol, Jonathan S. Towner
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Bats are natural hosts for Marburg virus (MARV), but the mechanism of bat-to-bat transmission is unclear. Here, Schuhet al. monitor MARV infection in a cohort of 38 bats over nine months, find ‘supershedders’ and show that MARV can horizontally t
Externí odkaz:
https://doaj.org/article/2bb3d5f00f8942d0b1156cddf271bc29
Autor:
Megan E.B. Jones, Brian R. Amman, Tara K. Sealy, Luke S. Uebelhoer, Amy J. Schuh, Timothy Flietstra, Brian H. Bird, JoAnn D. Coleman-McCray, Sherif R. Zaki, Stuart T. Nichol, Jonathan S. Towner
Publikováno v:
Viruses, Vol 11, Iss 3, p 214 (2019)
Egyptian rousette bats (Rousettus aegyptiacus) are natural reservoir hosts of Marburg virus (MARV), and Ravn virus (RAVV; collectively called marburgviruses) and have been linked to human cases of Marburg virus disease (MVD). We investigated the clin
Externí odkaz:
https://doaj.org/article/2c0fed7169fc48b1ba01613b1cf441e9
Autor:
Husam Taher, Eisa Mahyari, Craig Kreklywich, Luke S Uebelhoer, Matthew R McArdle, Matilda J Moström, Amruta Bhusari, Michael Nekorchuk, Xiaofei E, Travis Whitmer, Elizabeth A Scheef, Lesli M Sprehe, Dawn L Roberts, Colette M Hughes, Kerianne A Jackson, Andrea N Selseth, Abigail B Ventura, Hillary C Cleveland-Rubeor, Yujuan Yue, Kimberli A Schmidt, Jason Shao, Paul T Edlefsen, Jeremy Smedley, Timothy F Kowalik, Richard J Stanton, Michael K Axthelm, Jacob D Estes, Scott G Hansen, Amitinder Kaur, Peter A Barry, Benjamin N Bimber, Louis J Picker, Daniel N Streblow, Klaus Früh, Daniel Malouli
Publikováno v:
PLoS Pathogens, Vol 16, Iss 11, p e1008666 (2020)
Cytomegaloviruses (CMVs) are highly adapted to their host species resulting in strict species specificity. Hence, in vivo examination of all aspects of CMV biology employs animal models using host-specific CMVs. Infection of rhesus macaques (RM) with
Externí odkaz:
https://doaj.org/article/18b74986983c43189be2f692f0340704
Autor:
Harriet M, Babikako, Celine, Bourdon, Emmie, Mbale, Peace, Aber, Annet, Birabwa, Josephine, Chimoyo, Wieger, Voskuijl, Zaubina, Kazi, Paraskevi, Massara, John, Mukisa, Ezekiel, Mupere, Margaret, Nampijja, Ali Faisal, Saleem, Luke S, Uebelhoer, Robert, Bandsma, Judd L, Walson, James A, Berkley, Christina, Lancioni, Melissa, Gladstone, Meta, van den Heuvel
Publikováno v:
Pediatrics, 150(5). American Academy of Pediatrics
BACKGROUND AND OBJECTIVES Acute illness with malnutrition is a common indication for hospitalization among children in low- and middle-income countries. We investigated the association between wasting recovery trajectories and neurodevelopmental outc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc9428e93afce269c5a8c957a8a41121
https://doi.org/10.1542/peds.2021-055615
https://doi.org/10.1542/peds.2021-055615
Autor:
Bryce A. Binstadt, João M. Furtado, Michael P. Davey, Paige E. Snow, Biying Xu, Ruth J. Napier, Christina Lancioni, Kimberly A. Samson, Michelle C. Callegan, E. J. Lee, Mary J. Mattapallil, Holly L. Rosenzweig, Emily E. Vance, Sydney Lashley, Reiko Horai, Luke S. Uebelhoer, Brieanna Brown, Rachel R. Caspi, Richard K. Vehe, Justine R. Smith
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Nature Communications
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Nature Communications
Mutations in nucleotide-binding oligomerization domain-containing protein 2 (NOD2) cause Blau syndrome, an inflammatory disorder characterized by uveitis. The antimicrobial functions of Nod2 are well-established, yet the cellular mechanisms by which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b42c7e920b9a31c5f909265b99df89d
https://doaj.org/article/5c09fe5a329b4c398f56c7642549fe79
https://doaj.org/article/5c09fe5a329b4c398f56c7642549fe79
Autor:
Daniel Malouli, Roxanne M. Gilbride, Helen L. Wu, Joseph M. Hwang, Nicholas Maier, Colette M. Hughes, Daniel Newhouse, David Morrow, Abigail B. Ventura, Lynn Law, Jennifer Tisoncik-Go, Leanne Whitmore, Elise Smith, Inah Golez, Jean Chang, Jason S. Reed, Courtney Waytashek, Whitney Weber, Husam Taher, Luke S. Uebelhoer, Jennie L. Womack, Matthew R. McArdle, Junwei Gao, Courtney R. Papen, Jeffrey D. Lifson, Benjamin J. Burwitz, Michael K. Axthelm, Jeremy Smedley, Klaus Früh, Michael Gale, Louis J. Picker, Scott G. Hansen, Jonah B. Sacha
Publikováno v:
Cell Host & Microbe. 30:1207-1218.e7
Strain 68-1 rhesus cytomegalovirus expressing simian immunodeficiency virus (SIV) antigens (RhCMV/SIV) primes MHC-E-restricted CD8+ T cells that control SIV replication in 50%-60% of the vaccinated rhesus macaques. Whether this unconventional SIV-spe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbeca3c5f31b92deb05830f7216b8bf8
https://doi.org/10.1016/j.chom.2022.07.013
https://doi.org/10.1016/j.chom.2022.07.013
Autor:
Travis Whitmer, Jason Shao, Scott G. Hansen, Richard J. Stanton, Xiaofei E, Paul T. Edlefsen, Lesli M. Sprehe, Hillary C. Cleveland-Rubeor, Amitinder Kaur, Matilda J. Moström, Matthew R. McArdle, Colette M. Hughes, Peter A. Barry, Daniel Malouli, Andrea N. Selseth, Michael Nekorchuk, Eisa Mahyari, Jacob D. Estes, Michael K. Axthelm, Kerianne A. Jackson, Craig N. Kreklywich, Daniel N. Streblow, Yujuan Yue, Timothy F. Kowalik, Jeremy Smedley, Klaus Früh, Husam Taher, Benjamin N. Bimber, Luke S. Uebelhoer, Amruta Bhusari, Dawn L. Roberts, Louis J. Picker, Kimberli A. Schmidt, Elizabeth A. Scheef, Abigail B. Ventura
Publikováno v:
PLoS Pathogens
PLoS pathogens, vol 16, iss 11
PLoS Pathogens, Vol 16, Iss 11, p e1008666 (2020)
PLoS pathogens, vol 16, iss 11
PLoS Pathogens, Vol 16, Iss 11, p e1008666 (2020)
Cytomegaloviruses (CMVs) are highly adapted to their host species resulting in strict species specificity. Hence, in vivo examination of all aspects of CMV biology employs animal models using host-specific CMVs. Infection of rhesus macaques (RM) with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64e2377ed8fabf22acd1f59ded60bf34
http://europepmc.org/articles/PMC7723282
http://europepmc.org/articles/PMC7723282