Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Luke R K, Hughson"'
Publikováno v:
International Journal of Cell Biology, Vol 2012 (2012)
Accumulating evidence indicates that therapies designed to trigger apoptosis in tumor cells cause mitochondrial depolarization, nuclear damage, and the accumulation of misfolded protein aggregates, resulting in the activation of selective forms of au
Externí odkaz:
https://doaj.org/article/180367eaef8f46cc8279934c7f0ee30b
Publikováno v:
International Journal of Cell Biology, Vol 2011 (2011)
Hypoxia is a signature feature of growing tumors. This cellular state creates an inhospitable condition that impedes the growth and function of all cells within the immediate and surrounding tumor microenvironment. To adapt to hypoxia, cells activate
Externí odkaz:
https://doaj.org/article/e3b28313b8e24ddea220038aed65aee4
Autor:
Mary A. Elrick, Vincent I. Poon, Jillian M. Brandon, Luke R. K. Hughson, Ninan Abraham, Katelin N. Townsend, Izabelle Gadawski, Julian J. Lum, E. John Wherry, Sarah MacPherson, Katrin Schlie, Lindsay DeVorkin, Hélène C. F. Côté, Ashley Westerback, Noboru Mizushima
Publikováno v:
The Journal of Immunology. 194:4277-4286
The activation and expansion of effector CD8+ T cells are essential for controlling viral infections and tumor surveillance. During an immune response, T cells encounter extrinsic and intrinsic factors, including oxidative stress, nutrient availabili
Autor:
Luke R. K. Hughson, Katelin N. Townsend, Julian J. Lum, Vincent I. Poon, Katrin Schlie, Ashley Westerback
Publikováno v:
Immunological Reviews. 249:176-194
Tumors and the immune system are intertwined in a competition where tilting the fine balance between tumor-specific immunity and tolerance can ultimately decide the fate of the host. Defensive and suppressive immunological responses to cancer are exq
Publikováno v:
International Journal of Cell Biology, Vol 2012 (2012)
International Journal of Cell Biology
International Journal of Cell Biology
Accumulating evidence indicates that therapies designed to trigger apoptosis in tumor cells cause mitochondrial depolarization, nuclear damage, and the accumulation of misfolded protein aggregates, resulting in the activation of selective forms of au
Publikováno v:
International Journal of Cell Biology
International Journal of Cell Biology, Vol 2011 (2011)
International Journal of Cell Biology, Vol 2011 (2011)
Hypoxia is a signature feature of growing tumors. This cellular state creates an inhospitable condition that impedes the growth and function of all cells within the immediate and surrounding tumor microenvironment. To adapt to hypoxia, cells activate
Autor:
Katelin N, Townsend, Luke R K, Hughson, Katrin, Schlie, Vincent I, Poon, Ashley, Westerback, Julian J, Lum
Publikováno v:
Immunological reviews. 249(1)
Tumors and the immune system are intertwined in a competition where tilting the fine balance between tumor-specific immunity and tolerance can ultimately decide the fate of the host. Defensive and suppressive immunological responses to cancer are exq