Zobrazeno 1 - 10
of 478
pro vyhledávání: '"Luke P. Lee"'
Autor:
Peiran Zhang, Zhenhua Tian, Ke Jin, Kaichun Yang, Wesley Collyer, Joseph Rufo, Neil Upreti, Xianjun Dong, Luke P. Lee, Tony Jun Huang
Publikováno v:
Microsystems & Nanoengineering, Vol 10, Iss 1, Pp 1-16 (2024)
Abstract Laboratory automation technologies have revolutionized biomedical research. However, the availability of automation solutions at the single-cell level remains scarce, primarily owing to the inherent challenges of handling cells with such sma
Externí odkaz:
https://doaj.org/article/1cabda1c4499449db0397d3086c39f67
Autor:
Mengxi Wu, Zhiteng Ma, Zhenhua Tian, Joseph T. Rich, Xin He, Jianping Xia, Ye He, Kaichun Yang, Shujie Yang, Kam W. Leong, Luke P. Lee, Tony Jun Huang
Publikováno v:
Microsystems & Nanoengineering, Vol 10, Iss 1, Pp 1-19 (2024)
Abstract Advanced biofabrication techniques can create tissue-like constructs that can be applied for reconstructive surgery or as in vitro three-dimensional (3D) models for disease modeling and drug screening. While various biofabrication techniques
Externí odkaz:
https://doaj.org/article/99ecbb12ab86479bb3e05411cf845060
Autor:
Minsup Shin, Wooyeon Kim, Kwanghee Yoo, Hye-Seong Cho, Sohyeon Jang, Han-Joo Bae, Jaehyun An, Jong-chan Lee, Hyejin Chang, Dong-Eun Kim, Jaehi Kim, Luke P. Lee, Bong-Hyun Jun
Publikováno v:
Nano Convergence, Vol 11, Iss 1, Pp 1-13 (2024)
Abstract Lateral flow assay (LFA) systems use metal nanoparticles for rapid and convenient target detection and are extensively studied for the diagnostics of various diseases. Gold nanoparticles (AuNPs) are often used as probes in LFAs, displaying a
Externí odkaz:
https://doaj.org/article/737b79f3b6ab47af85ee68c9a05b6700
Autor:
Taewoon Kim, Harshitha Kallubhavi Choodinatha, Kwang Sik Kim, Kyusoon Shin, Hyeon Ji Kim, Jee Yoon Park, Jong Wook Hong, Luke P. Lee
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Preeclampsia is a hypertensive disorder of pregnancy that can lead to stillbirth and preterm birth if not treated promptly. Currently, the diagnosis of preeclampsia relies on clinical symptoms such as hypertension and proteinuria, along with
Externí odkaz:
https://doaj.org/article/fcc2478748fc4512968862591e50cbbf
Autor:
Mengxi Wu, Zhiteng Ma, Xianchen Xu, Brandon Lu, Yuyang Gu, Janghoon Yoon, Jianping Xia, Zhehan Ma, Neil Upreti, Imran J. Anwar, Stuart J. Knechtle, Eileen T. Chambers, Jean Kwun, Luke P. Lee, Tony Jun Huang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract Therapeutic apheresis aims to selectively remove pathogenic substances, such as antibodies that trigger various symptoms and diseases. Unfortunately, current apheresis devices cannot handle small blood volumes in infants or small animals, hi
Externí odkaz:
https://doaj.org/article/94286a8fbbe7487ea7886bf0eb6155d4
Publikováno v:
Nano Convergence, Vol 11, Iss 1, Pp 1-15 (2024)
Abstract Extracellular vesicles (EVs) are promising tools for the early diagnosis of diseases, and bacterial membrane vesicles (MVs) are especially important in health and environment monitoring. However, detecting EVs or bacterial MVs presents signi
Externí odkaz:
https://doaj.org/article/9c9b0e6d5cb64b83b03263b89b45586b
Autor:
Sarnai Amartumur, Huong Nguyen, Thuy Huynh, Testaverde S. Kim, Ran-Sook Woo, Eungseok Oh, Kyeong Kyu Kim, Luke P. Lee, Chaejeong Heo
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-34 (2024)
Abstract Developing diagnostics and treatments for neurodegenerative diseases (NDs) is challenging due to multifactorial pathogenesis that progresses gradually. Advanced in vitro systems that recapitulate patient-like pathophysiology are emerging as
Externí odkaz:
https://doaj.org/article/33b5c01ee25d4cfe930e683927721137
Autor:
Joseph Rufo, Peiran Zhang, Zeyu Wang, Yuyang Gu, Kaichun Yang, Joseph Rich, Chuyi Chen, Ruoyu Zhong, Ke Jin, Ye He, Jianping Xia, Ke Li, Jiarong Wu, Yingshi Ouyang, Yoel Sadovsky, Luke P. Lee, Tony Jun Huang
Publikováno v:
Microsystems & Nanoengineering, Vol 10, Iss 1, Pp 1-11 (2024)
Abstract Extracellular vesicles (EVs) have been identified as promising biomarkers for the noninvasive diagnosis of various diseases. However, challenges in separating EVs from soluble proteins have resulted in variable EV recovery rates and low puri
Externí odkaz:
https://doaj.org/article/1efd678afc8f48d5819840f73155898c
Autor:
Ye He, Shujie Yang, Pengzhan Liu, Ke Li, Ke Jin, Ryan Becker, Jinxin Zhang, Chuanchuan Lin, Jianping Xia, Zhehan Ma, Zhiteng Ma, Ruoyu Zhong, Luke P. Lee, Tony Jun Huang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract While mesenchymal stem cells (MSCs) have gained enormous attention due to their unique properties of self-renewal, colony formation, and differentiation potential, the MSC secretome has become attractive due to its roles in immunomodulation,
Externí odkaz:
https://doaj.org/article/9aba877a6999499c843d510d18ccc5cb
Autor:
Lixue Wang, Guosheng Wang, Wenjun Mao, Yundi Chen, Md. Mofizur Rahman, Chuandong Zhu, Peter M. Prisinzano, Bo Kong, Jing Wang, Luke P. Lee, Yuan Wan
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Cell-derived small extracellular vesicles have been exploited as potent drug vehicles. However, significant challenges hamper their clinical translation, including inefficient cytosolic delivery, poor target-specificity, low yield, and incon
Externí odkaz:
https://doaj.org/article/bf5ab3291395474baaa4e0192fa89dd2