Zobrazeno 1 - 10
of 186
pro vyhledávání: '"Luke P Brewster"'
Autor:
Sean M. Carr, PhD, Katherine Owsiany, MD, PhD, Ottis Scrivner, PhD, Dylan McLaughlin, MD, Hanjoong Jo, PhD, Luke P. Brewster, Katherine E. Hekman, MD, PhD
Publikováno v:
JVS - Vascular Science, Vol 5, Iss , Pp 100193- (2024)
Background: Induced pluripotent stem cells (iPSCs) directed to endothelial identity (iPSC-ECs) are emerging as a potent tool for regenerative medicine in vascular disease. However, iPSC-ECs lose expression of key identity markers under standard in vi
Externí odkaz:
https://doaj.org/article/64bb1a5600c84eac8dd7e571d75bdc88
Autor:
Gloriani Sánchez Marrero, Nicolas Villa-Roel, Feifei Li, Christian Park, Dong-Won Kang, Katherine E. Hekman, Hanjoong Jo, Luke P. Brewster
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
Peripheral arterial disease (PAD) is an age-related medical condition affecting mostly muscular arteries of the limb. It is the 3rd leading cause of atherosclerotic morbidity. The mechanical environment of endothelial cells (ECs) in PAD is characteri
Externí odkaz:
https://doaj.org/article/61b2ee7740b748fc945a0bebbdf83520
Autor:
Dylan K. McLaughlin, MD, Carson Hoffmann, MD, Maiko Sasaki, MS, MPH, Feifei Li, MD, Jing Ma, BS, Xiangqin Cui, PhD, Roy L. Sutliff, PhD, Luke P. Brewster, MD, PhD
Publikováno v:
JVS - Vascular Science, Vol 4, Iss , Pp 100122- (2023)
Objective: Arterial ring testing is the gold standard for measuring arterial function. Increased arterial tone through arterial contraction and impaired endothelial relaxation (endothelial dysfunction) are key metrics of impaired arterial health in p
Externí odkaz:
https://doaj.org/article/33c0a6f6f8c649818adfc71643e6d92e
Publikováno v:
JVS - Vascular Science, Vol 3, Iss , Pp 410- (2022)
Externí odkaz:
https://doaj.org/article/07f43dcf043744e1bdcfdb239376b355
Autor:
Mark A, Eid, Michael J, Barry, Gale L, Tang, Peter K, Henke, Jason M, Johanning, Edith, Tzeng, Salvatore T, Scali, David H, Stone, Bjoern D, Suckow, Eugene S, Lee, Shipra, Arya, Benjamin S, Brooke, Peter R, Nelson, Emily L, Spangler, Leila, Murebee, Hasan H, Dosluoglu, Joseph D, Raffetto, Panos, Kougais, Luke P, Brewster, Olamide, Alabi, Alan, Dardik, Vivienne J, Halpern, Jessica B, O'Connell, Daniel M, Ihnat, Wei, Zhou, Brenda E, Sirovich, Kunal, Metha, Kayla O, Moore, Amy, Voorhees, Philip P, Goodney, Ashley, Langston
Publikováno v:
JAMA surgery. 157(9)
Patients with abdominal aortic aneurysm (AAA) can choose open repair or endovascular repair (EVAR). While EVAR is less invasive, it requires lifelong surveillance and more frequent aneurysm-related reinterventions than open repair. A decision aid may
Autor:
Ottis Scrivner, Emma Fletcher, Carson Hoffmann, Feifei Li, Trevor Wilkinson, Dimitrios Miserlis, Robert S Smith, William T Bohannon, Roy Sutliff, William D Jordan, Panagiotis Koutakis, Luke P Brewster
Publikováno v:
Journal of the American College of Surgeons. 236:588-598
Autor:
Ahmed Ismaeel, Evlampia Papoutsi, Dimitrios Miserlis, Ramon Lavado, Gleb Haynatzki, George P. Casale, William T. Bohannon, Robert S. Smith, Jack Leigh Eidson, Robert Brumberg, Aaron Hayson, Jeffrey S. Kirk, Carlos Castro, Ian Sawicki, Charalambos Konstantinou, Luke P. Brewster, Iraklis I. Pipinos, Panagiotis Koutakis
Publikováno v:
Antioxidants, Vol 9, Iss 7, p 590 (2020)
Peripheral artery disease (PAD) pathophysiology extends beyond hemodynamics to include other operating mechanisms, including endothelial dysfunction. Oxidative stress may be linked to endothelial dysfunction by reducing nitric oxide (NO) bioavailabil
Externí odkaz:
https://doaj.org/article/610c7cbb1b1141d3b5cb076be7c8210c
Autor:
Shipra Arya, Zachary Binney, Anjali Khakharia, Luke P. Brewster, Phil Goodney, Rachel Patzer, Jason Hockenberry, Peter W. F. Wilson
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 7, Iss 2 (2018)
BackgroundBlack race has been shown to be a risk factor for amputation in peripheral artery disease (PAD); however, race has been argued to be a marker for socioeconomic status (SES) rather than true disparity. The aim of this study is to study the i
Externí odkaz:
https://doaj.org/article/157229e1a4c142b0a18589809d92a5e2
Autor:
Mengyu Di, Manila Gaddh, Yue Xie, Luke P. Brewster, Yazan Duwayri, Milad Sharifpour, Richard A. Meena, Olamide Alabi, Xiangqin Cui
Publikováno v:
Seminars in Vascular Surgery
Patients with coronavirus disease 2019 (COVID-19) seem to be at high risk for venous thromboembolism (VTE) development, but there is a paucity of data exploring both the natural history of COVID-19-associated VTE and the risk for poor outcomes after
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 42
CCN2 or connective tissue growth factor is up-regulated in response to disturbed flow and arterial stiffening. Carotid artery disease and peripheral arterial disease (PAD) are associated with disturbed flow and arterial stiffening. We have identified