Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Luke Milross"'
Autor:
Luke Milross, Bethany Hunter, David McDonald, George Merces, Amanda Thomson, Catharien M.U. Hilkens, John Wills, Paul Rees, Kasim Jiwa, Nigel Cooper, Joaquim Majo, Helen Ashwin, Christopher J.A. Duncan, Paul M. Kaye, Omer Ali Bayraktar, Andrew Filby, Andrew J. Fisher
Publikováno v:
EBioMedicine, Vol 99, Iss , Pp 104945- (2024)
Summary: Background: Lung damage in severe COVID-19 is highly heterogeneous however studies with dedicated spatial distinction of discrete temporal phases of diffuse alveolar damage (DAD) and alternate lung injury patterns are lacking. Existing studi
Externí odkaz:
https://doaj.org/article/1b7f1a779bc24e5da70f8643842a6531
Autor:
Luke Milross, Joaquim Majo, Julian Pulle, Sam Hoggard, Nigel Cooper, Bethany Hunter, Christopher J.A. Duncan, Andrew Filby, Andrew J. Fisher
Publikováno v:
ERJ Open Research, Vol 8, Iss 4 (2022)
Background Post mortem examination of lung and heart tissue has been vital to developing an understanding of COVID-19 pathophysiology; however studies to date have almost uniformly used tissue obtained from hospital-based deaths where individuals hav
Externí odkaz:
https://doaj.org/article/15dad7c6b9c14122ae8098f52ffe51a3
Publikováno v:
Transplantology, Vol 2, Iss 4, Pp 387-395 (2021)
Lung transplantation offers a lifesaving therapy for patients with end-stage lung disease but its availability is presently limited by low organ utilization rates with donor lungs frequently excluded due to unsuitability at assessment. When transplan
Externí odkaz:
https://doaj.org/article/79858090a687469dbf39fee950ff5fcd
Publikováno v:
European Respiratory Review, Vol 31, Iss 165 (2022)
Lung transplantation is the optimal treatment for selected patients with end-stage chronic lung diseases. However, chronic lung allograft dysfunction remains the leading obstacle to improved long-term outcomes. Traditionally, lung allograft rejection
Externí odkaz:
https://doaj.org/article/f04d30a02df54d7cbbca59f21e50f06e
Autor:
Luke Milross, Bethany Hunter, David McDonald, George Merces, Amanda Thompson, Catharien M.U. Hilkens, John Wills, Paul Rees, Kasim Jiwa, Nigel Cooper, Joaquim Majo, Helen Ashwin, Christopher J.A. Duncan, Paul M. Kaye, Omer Ali Bayraktar, Andrew Filby, Andrew J. Fisher
BackgroundLung damage in severe COVID-19 is highly heterogeneous however studies with dedicated spatial distinction of discrete temporal phases of diffuse alveolar damage (DAD) and alternate lung injury patterns are lacking. Existing studies have als
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9cf429a92bcf72d3c83f8938e4e163f
https://doi.org/10.1101/2023.05.05.23289594
https://doi.org/10.1101/2023.05.05.23289594
Autor:
Shoumit Dey, Helen Ashwin, Luke Milross, Bethany Hunter, Joaquim Majo, Andrew J Filby, Andrew J Fisher, Paul M Kaye, Dimitris Lagos
Publikováno v:
Clinical and Experimental Immunology.
T cells play key protective but also pathogenic roles in COVID-19. We studied the expression of long non-coding RNAs (lncRNAs) in COVID-19 T-cell transcriptomes by integrating previously published single-cell RNA sequencing datasets. The long interge
Autor:
Bethany Hunter, Ioana Nicorescu, Emma Foster, David McDonald, Gillian Hulme, Fuller Andrew, Amanda Thomson, Catharien M.U. Hilkens, Joaquim Majo, Luke Milross, Andrew Fisher, John Wills, Paul Rees, Andrew Filby, George Merces
Analysis of Imaging Mass Cytometry (IMC) data and other low-resolution multiplexed tissue imaging technologies is often confounded by poor single cell segmentation and sub-optimal approaches for data visualisation and exploration. This can lead to in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35ead2d23b18bdaf7981447730180fc8
https://doi.org/10.1101/2023.02.21.526083
https://doi.org/10.1101/2023.02.21.526083
Autor:
Shoumit Dey, Helen Ashwin, Luke Milross, Bethany Hunter, Joaquim Majo, Andrew J Filby, Andrew J Fisher, Paul M. Kaye, Dimitris Lagos
T cells play key protective but also pathogenic roles in COVID-19. We studied expression of long non-coding RNAs (lncRNAs) in COVID-19 T cell transcriptomes by integrating previously published single-cell RNA sequencing datasets. The long intergenic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a98359f82bf2d12a0341a01b2fd0ef87
https://doi.org/10.1101/2023.01.06.23284229
https://doi.org/10.1101/2023.01.06.23284229
Autor:
Helen Ashwin, Luke Milross, Julie Wilson, Joaquim Majo, Jimmy Tsz Hang Lee, Grant Calder, Bethany Hunter, Sally James, Dimitris Lagos, Nathalie Signoret, Andrew Filby, Omer Ali Bayraktar, Andrew J. Fisher, Paul M. Kaye
Diffuse alveolar damage (DAD) is the histological expression of acute respiratory distress syndrome and characterises lung pathology due to infection with SARS-CoV-2, and other respiratory pathogens of clinical significance. DAD reflects a time-depen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8730fface50f6052e19b7e212d7cba9a
https://doi.org/10.1101/2022.12.09.22283280
https://doi.org/10.1101/2022.12.09.22283280
Publikováno v:
Transplantology, Vol 2, Iss 37, Pp 387-395 (2021)
Lung transplantation offers a lifesaving therapy for patients with end-stage lung disease but its availability is presently limited by low organ utilization rates with donor lungs frequently excluded due to unsuitability at assessment. When transplan