Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Luke McCarty"'
Autor:
Michelle Irwin, Tomasz K. Baginski, Leslie Welch, Daniel P. Hewitt, Christina Tsai, Luke McCarty, Xiao Dong
Publikováno v:
Journal of Chromatography B. 1092:158-167
Free thiol content, and its consistency, is one of the product quality attributes of interest during technical development of manufactured recombinant monoclonal antibodies (mAbs). We describe a new, mid/high-throughput reversed-phase-high performanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97009584ddb4cd7c761bce9561ce26bc
https://doi.org/10.1016/j.jchromb.2018.05.039
https://doi.org/10.1016/j.jchromb.2018.05.039
Autor:
Jianhui Zhou, Jacob E. Corn, Zhilan Hu, Christoph Spiess, Yiyuan Yin, Teemu T. Junttila, Dionysos Slaga, Kedan Lin, Paul Carter, Michael Dillon, Luke McCarty, Meric A. Ovacik, Wendy Sandoval, Amy Shen, Guanghui Han, Diego Ellerman
Publikováno v:
mAbs
Bispecific IgG production in single host cells has been a much sought-after goal to support the clinical development of these complex molecules. Current routes to single cell production of bispecific IgG include engineering heavy chains for heterodim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dc9875c0041693f4385ea982de0d838
https://doi.org/10.1080/19420862.2016.1267089
https://doi.org/10.1080/19420862.2016.1267089
Autor:
Paul Carter, Luis F. Schachner, Yiyuan Yin, Christoph Spiess, Guanghui Han, Jennie R. Lill, Luke McCarty, Jianhui Zhou, Diego Ellerman, Wendy Sandoval, Michael Dillon
Publikováno v:
Analytical Chemistry. 88:12122-12127
Bispecific antibodies, including bispecific IgG, show some promise in clinical trials as a means to extend the therapeutic potential of antibodies. Bispecific IgG can be made by separate expression and purification of each parent half antibody follow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba22455a3fccea3b2a6d7a34ae27e7cf
https://doi.org/10.1021/acs.analchem.6b02866
https://doi.org/10.1021/acs.analchem.6b02866
Autor:
Paul Carter, Jianhui Zhou, Lou Gavino, Christoph Spiess, Michael Dillon, Diego Ellerman, Wendy Sandoval, Guanghui Han, Luke McCarty, Yiyuan Yin
Publikováno v:
mAbs
Bispecific IgG are heterotetramers comprising 2 pairs of heavy and light chains. Co-expression of the 4 component chains in a single host cell typically yields the desired bispecific IgG plus up to 9 additional incorrect chain pairings. Several prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad2e6d16e6c472c3bfebfbd2dddad60c
http://europepmc.org/articles/PMC5098441
http://europepmc.org/articles/PMC5098441
Akademický článek
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Publikováno v:
Molecular and Cellular Proteomics (MCP Online); January 2014, Vol. 13 Issue: 1 pS33-S40, 8p
Autor:
Dillon, Michael, Yin, Yiyuan, Zhou, Jianhui, McCarty, Luke, Ellerman, Diego, Slaga, Dionysos, Junttila, Teemu T., Han, Guanghui, Sandoval, Wendy, Ovacik, Meric A., Lin, Kedan, Hu, Zhilan, Shen, Amy, Corn, Jacob E., Spiess, Christoph, Carter, Paul J.
Publikováno v:
mAbs; Feb/Mar2017, Vol. 9 Issue 2, p213-230, 18p
Autor:
Yin, Yiyuan, Han, Guanghui, Zhou, Jianhui, Dillon, Michael, McCarty, Luke, Gavino, Lou, Ellerman, Diego, Spiess, Christoph, Sandoval, Wendy, Carter, Paul J.
Publikováno v:
mAbs; Nov/Dec2016, Vol. 8 Issue 8, p1467-1476, 10p
Autor:
Armand Léon van Ommen, Brian R. Brock
John Swinton has indelibly shaped the discipline of practical theology not only in the United Kingdom but globally, and has been especially influential in the areas of disability theology, dementia, health care, and chaplaincy. Swinton presses one qu
