Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Luke Manlove"'
Publikováno v:
Cancer Research. 78:1789-1789
Brentuximab vedotin (BV) is an antibody-drug conjugate (ADC) directed against CD30, a TNF receptor superfamily (TNFRSF) member highly expressed on Reed Sternberg cells in Hodgkin lymphoma (HL) and also commonly expressed in a number of other lymphoid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7d07fbb556e8dfaa59965503bca3df5
https://doi.org/10.1158/1538-7445.am2018-1789
https://doi.org/10.1158/1538-7445.am2018-1789
Autor:
Birgit Schultes, Seth Ettenberg, Shyra Gardai, Lori Westendorf, Katie O'Callaghan, Heather Huet, Ryan M. Boomer, Taylor Hickman, Django Sussman, Allison Nelson, Luke Manlove, Kathleen E. McGinness, Tooba A. Cheema
Publikováno v:
Cancer Research. 77:4605-4605
B cell maturation antigen (BCMA) has recently emerged as an attractive therapeutic target in multiple myeloma. BCMA has restricted expression on plasma cells with little to no expression on other normal tissues, but is upregulated on the surface of m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a5b967a976b2949823a1f347bdcc099c
https://doi.org/10.1158/1538-7445.am2017-4605
https://doi.org/10.1158/1538-7445.am2017-4605
Autor:
Pamela Rosato, Luke Manlove, Christine Nelson, Christopher Pennell, Vaiva Vezys, David Masopust
Publikováno v:
The Journal of Immunology. 198:196.10-196.10
The immunosuppressive tumor microenvironment is barrier to successful cancer therapies. Newly discovered tissue resident memory CD8+ T cells (TRM) function to create a potent immunostimulatory environment to protect against local reinfection. As TRM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a457384024c174f989d5410af6347acb
https://doi.org/10.4049/jimmunol.198.supp.196.10
https://doi.org/10.4049/jimmunol.198.supp.196.10
Autor:
Luke Manlove, Katherine Vrieze, Kezia Manlove, Kristen Pauken, Jason Schenkel, Richard Williams, Marc Jenkins, Michael Farrar
Publikováno v:
The Journal of Immunology. 194:210.22-210.22
Current therapies induce only transient responses in patients with BCR-ABL+ B Acute Lymphoblastic Leukemia. Thus augmenting immune responses to the BCR-ABL fusion peptide could be therapeutically beneficial. The fusion between BCR and ABL encodes a n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c4c64fa3731f336fa5bc6dc292c7b49
https://doi.org/10.4049/jimmunol.194.supp.210.22
https://doi.org/10.4049/jimmunol.194.supp.210.22
Autor:
Michael Farrar, Shawn Mahmud, Luke Manlove, Heather Schmitz, Yan Xing, Yanyan Wang, David Owen, Jason Schenkel, Jonathan Boomer, Jonathan Green, Hideo Yagita, Hongbo Chi, Kristin Hogquist
Publikováno v:
The Journal of Immunology. 192:177.14-177.14
Regulatory T cells express several TNF receptor superfamily (TNFRSF) members, but their role in thymic Treg development is undefined. We demonstrate that Treg progenitors express high levels of the TNFRSF members GITR, OX40, and TNFR2. Expression of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a3b35dcda12b63feab23fb97fb845497
https://doi.org/10.4049/jimmunol.192.supp.177.14
https://doi.org/10.4049/jimmunol.192.supp.177.14
Autor:
Luke Manlove, Michael Farrar
Publikováno v:
The Journal of Immunology. 190:174.18-174.18
The related co-repressors NCOR1 and NCOR2 interact with transcription factors required for lymphocyte development and function. To examine the role of NCOR2 in lymphocytes, we generated CD4-Cre x Ncor2FL/FL and Mb1-Cre x Ncor2FL/FL mice. Deletion of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a005cd4b217dbd83e85bbe652035149f
https://doi.org/10.4049/jimmunol.190.supp.174.18
https://doi.org/10.4049/jimmunol.190.supp.174.18
Publikováno v:
The Journal of Immunology. 190:52.35-52.35
CD4+FOXP3+ regulatory T cells (Tregs) express several TNF receptor superfamily (TNFRSF) members, but what role these molecules play in thymic Treg development is unclear. We found that CD25+FOXP3- Treg progenitors and CD25+FOXP3+ thymic Tregs highly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49f727a26019681b5f9d95bcc8205762
https://doi.org/10.4049/jimmunol.190.supp.52.35
https://doi.org/10.4049/jimmunol.190.supp.52.35
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Publikováno v:
Blood; December 2017, Vol. 130 Issue: 1, Number 1 Supplement 1 p3881-3881, 1p