Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Luke M. Cowan"'
Autor:
Luke M. Cowan, Peter R. Strege, Radda Rusinova, Olaf S. Andersen, Gianrico Farrugia, Arthur Beyder
Publikováno v:
Channels, Vol 16, Iss 1, Pp 9-26 (2022)
SCN5A-encoded NaV1.5 is a voltage-gated Na+ channel that drives the electrical excitability of cardiac myocytes and contributes to slow waves of the human gastrointestinal smooth muscle cells. NaV1.5 is mechanosensitive: mechanical force modulates se
Externí odkaz:
https://doaj.org/article/d7b82b4fe10747dbb4e5da0258790029
Autor:
Peter R Strege, Luke M Cowan, Constanza Alcaino, Amelia Mazzone, Christopher A Ahern, Lorin S Milescu, Gianrico Farrugia, Arthur Beyder
Publikováno v:
eLife, Vol 12 (2023)
Voltage-gated ion channels (VGICs) orchestrate electrical activities that drive mechanical functions in contractile tissues such as the heart and gut. In turn, contractions change membrane tension and impact ion channels. VGICs are mechanosensitive,
Externí odkaz:
https://doaj.org/article/b8dfecfda4b3488889b0906796a76808
Autor:
Marco A Navarro, Autoosa Salari, Jenna L Lin, Luke M Cowan, Nicholas J Penington, Mirela Milescu, Lorin S Milescu
Publikováno v:
eLife, Vol 9 (2020)
Voltage-gated sodium channels play a critical role in cellular excitability, amplifying small membrane depolarizations into action potentials. Interactions with auxiliary subunits and other factors modify the intrinsic kinetic mechanism to result in
Externí odkaz:
https://doaj.org/article/24456da1dd444b96a12bd4105188c12d
Autor:
Peter R Strege, Luke M Cowan, Constanza Alcaino, Amelia Mazzone, Christopher A Ahern, Lorin S Milescu, Gianrico Farrugia, Arthur Beyder
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb9b84cda371b1455221d853f6c46466
https://doi.org/10.7554/elife.79271.sa2
https://doi.org/10.7554/elife.79271.sa2
Autor:
Peter R Strege, Luke M Cowan, Constanza Alcaino, Amelia Mazzone, Christopher A Ahern, Lorin S Milescu, Gianrico Farrugia, Arthur Beyder
Voltage-gated ion channels (VGICs) orchestrate electrical activities that drive mechanical functions in contractile tissues such as the heart and gut. In turn, contractions change membrane tension and impact ion channels. VGICs are mechanosensitive,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4aa01c13a3fb5c865df0c65e92b64791
https://doi.org/10.1101/2022.05.10.491345
https://doi.org/10.1101/2022.05.10.491345
Autor:
Peter R. Strege, Vikram Joshi, Luke M. Cowan, Kaitlyn R. Knutson, Andrew J. Wegner, Gianrico Farrugia, Arthur Beyder
Publikováno v:
Gastroenterology. 162:S-325
Autor:
Autoosa Salari, Nicholas J. Penington, Marco A. Navarro, Luke M Cowan, Mirela Milescu, Jenna L. Lin, Lorin S. Milescu
Publikováno v:
eLife
eLife, Vol 9 (2020)
eLife, Vol 9 (2020)
Voltage-gated sodium channels play a critical role in cellular excitability, amplifying small membrane depolarizations into action potentials. Interactions with auxiliary subunits and other factors modify the intrinsic kinetic mechanism to result in