Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Luke K, Genutis"'
Autor:
Clara D. Bloomfield, Albert de la Chapelle, John C. Byrd, Richard M. Stone, Andrew J. Carroll, Eunice S. Wang, Geoffrey L. Uy, Jonathan E. Kolitz, Bayard L. Powell, Kellie J. Archer, Shelley Orwick, Sophia E. Maharry, Luke K. Genutis, Brian Giacopelli, Christopher C. Oakes, Dimitrios Papaioannou, Marius Bill, James S. Blachly, Deedra Nicolet, Chi Song, Sandya Liyanarachchi, Krzysztof Mrózek, Ann-Kathrin Eisfeld, Jessica Kohlschmidt, Christopher J. Walker
Supplementary Methods, Supplementary References Supplementary Table S1: Inherited regions of homozygosity in >1% of 1,798 non-leukemic individuals Supplementary Table S2: Acquired uniparental disomies detected in 425 cytogenetically normal AML patien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eb68bd339f94f4dd7b1f367f40a5ade
https://doi.org/10.1158/1078-0432.22471776
https://doi.org/10.1158/1078-0432.22471776
Autor:
Clara D. Bloomfield, Albert de la Chapelle, John C. Byrd, Richard M. Stone, Andrew J. Carroll, Eunice S. Wang, Geoffrey L. Uy, Jonathan E. Kolitz, Bayard L. Powell, Kellie J. Archer, Shelley Orwick, Sophia E. Maharry, Luke K. Genutis, Brian Giacopelli, Christopher C. Oakes, Dimitrios Papaioannou, Marius Bill, James S. Blachly, Deedra Nicolet, Chi Song, Sandya Liyanarachchi, Krzysztof Mrózek, Ann-Kathrin Eisfeld, Jessica Kohlschmidt, Christopher J. Walker
Purpose:Uniparental disomy (UPD) is a way cancer cells duplicate a mutated gene, causing loss of heterozygosity (LOH). Patients with cytogenetically normal acute myeloid leukemia (CN-AML) do not have microscopically detectable chromosome abnormalitie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84cce1f02415f98f1aeac55066dfea0d
https://doi.org/10.1158/1078-0432.c.6528006
https://doi.org/10.1158/1078-0432.c.6528006
Autor:
Clara D. Bloomfield, Albert de la Chapelle, John C. Byrd, Richard M. Stone, Andrew J. Carroll, Eunice S. Wang, Geoffrey L. Uy, Jonathan E. Kolitz, Bayard L. Powell, Kellie J. Archer, Shelley Orwick, Sophia E. Maharry, Luke K. Genutis, Brian Giacopelli, Christopher C. Oakes, Dimitrios Papaioannou, Marius Bill, James S. Blachly, Deedra Nicolet, Chi Song, Sandya Liyanarachchi, Krzysztof Mrózek, Ann-Kathrin Eisfeld, Jessica Kohlschmidt, Christopher J. Walker
Mutations detected in 425 CN-AML patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::035dff51fb36ae6eef5ba48627ecfe72
https://doi.org/10.1158/1078-0432.22471770
https://doi.org/10.1158/1078-0432.22471770
Autor:
Isabella V. Hendrickson, Pamela Brock, Sandya Liyanarachchi, Albert de la Chapelle, Lianbo Yu, Huiling He, Mehek S. Sheikh, Luke K Genutis, Daniel F. Comiskey
Publikováno v:
Journal of Medical Genetics. 57:519-527
BackgroundPapillary thyroid carcinoma (PTC) demonstrates high heritability and a low somatic mutation burden relative to other cancers. Therefore, the genetic risk predisposing to PTC is likely due to a combination of low penetrance variants. A recen
Autor:
Sophia E. Maharry, Clara D. Bloomfield, Marius Bill, Sandya Liyanarachchi, Christopher C. Oakes, Chi Song, Christopher J. Walker, Albert de la Chapelle, Geoffrey L. Uy, Brian Giacopelli, James S. Blachly, Bayard L. Powell, Eunice S. Wang, Shelley Orwick, Jonathan E. Kolitz, Richard Stone, Deedra Nicolet, Kellie J. Archer, Ann-Kathrin Eisfeld, John C. Byrd, Luke K Genutis, Jessica Kohlschmidt, Dimitrios Papaioannou, Krzysztof Mrózek, Andrew J. Carroll
Publikováno v:
Clin Cancer Res
Purpose:Uniparental disomy (UPD) is a way cancer cells duplicate a mutated gene, causing loss of heterozygosity (LOH). Patients with cytogenetically normal acute myeloid leukemia (CN-AML) do not have microscopically detectable chromosome abnormalitie
Autor:
Brynn Hollingsworth, Jennifer A. Sipos, Luke K Genutis, Yi Seok Chang, Christopher J. Walker, Pamela Brock, Electron Kebebew, Patience Green, Fadi Nabhan, W. G. Li, Sandya Liyanarachchi, Gilbert J. Cote, Steven I. Sherman, Sissy M. Jhiang, Albert de la Chapelle, Shuai Xue, Zachary A. Hurst, Huiling He, Eric Menq
Publikováno v:
Thyroid. 29:530-539
Background: Thyroid cancer patients with radioiodine-refractory (RAI-R) disease, resulting from insufficient RAI delivery and/or RAI resistance, have increased mortality and limited treatment options. To date, studies have largely focused on tumor mu
Autor:
Ann-Kathrin Eisfeld, Luke K Genutis, Christopher J. Walker, Clara D. Bloomfield, Jonathan E. Kolitz, Ramiro Garzon, Deedra Nicolet, Albert de la Chapelle, Jessica Kohlschmidt, Richard Stone, Krzysztof Mrózek, Dimitrios Papaioannou, Marius Bill, Geoffrey L. Uy, Andrew J. Carroll, Hatice Gulcin Ozer, Bayard L. Powell, John C. Byrd
Publikováno v:
Blood Adv
Although ∼80% of adult patients with cytogenetically normal acute myeloid leukemia (CN-AML) achieve a complete remission (CR), more than half of them relapse. Better identification of patients who are likely to relapse can help to inform clinical d
Autor:
James M. Church, Lisa LaGuardia, Päivi Peltomäki, Pamela Brock, Anna Lepistö, Johanna Arola, Ann-Kathrin Eisfeld, Luke K Genutis, Ayse Selen Yilmaz, Alisa Olkinuora, Taina T. Nieminen, Margaret O'Malley, Paul E. Wakely, Laura Koskenvuo, Christopher J. Walker, Albert de la Chapelle
Background: Familial adenomatous polyposis (FAP) is a condition typically caused by pathogenic germline mutations in the APC gene. In addition to colon polyps, individuals with FAP have a substantially increased risk of developing papillary thyroid c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe1763a3821bdae6f6759d0bebcdda74
http://hdl.handle.net/10138/327265
http://hdl.handle.net/10138/327265
Autor:
Taina T, Nieminen, Christopher J, Walker, Alisa, Olkinuora, Luke K, Genutis, Margaret, O'Malley, Paul E, Wakely, Lisa, LaGuardia, Laura, Koskenvuo, Johanna, Arola, Anna H, Lepistö, Pamela, Brock, Ayse Selen, Yilmaz, Ann-Kathrin, Eisfeld, James M, Church, Päivi, Peltomäki, Albert, de la Chapelle
Publikováno v:
Thyroid : official journal of the American Thyroid Association. 30(3)
Autor:
Brian Giacopelli, Markus Scholz, Pamela Brock, Sebastian Schwind, Andrew J. Carroll, Marius Bill, Christopher C. Oakes, John C. Byrd, Dietger Niederwieser, Christopher J. Walker, Richard Stone, Krzysztof Mrózek, Eunice S. Wang, Ann-Kathrin Eisfeld, Jonathan E. Kolitz, Clara D. Bloomfield, Bayard L. Powell, Luke K Genutis, Sandya Liyanarachchi, Albert de la Chapelle, Jessica Kohlschmidt, Deedra Nicolet
Publikováno v:
Leukemia. 33:771-775