Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Luke J. Kubiatowicz"'
Publikováno v:
Exploration, Vol 2, Iss 6, Pp n/a-n/a (2022)
Abstract The rational design and application of mRNA‐based medicine have recently yielded some key successes in the clinical management of human diseases. mRNA technology allows for the facile and direct production of proteins in vivo, thus circumv
Externí odkaz:
https://doaj.org/article/6e4420c726104649963502ae01d0995c
Autor:
Woo‐jin Jeong, Jiyoon Bu, Roya Jafari, Pavel Rehak, Luke J. Kubiatowicz, Adam J. Drelich, Randall H. Owen, Ashita Nair, Piper A. Rawding, Michael J. Poellmann, Caroline M. Hopkins, Petr Král, Seungpyo Hong
Publikováno v:
Advanced Science, Vol 9, Iss 4, Pp n/a-n/a (2022)
Abstract The multivalent binding effect has been the subject of extensive studies to modulate adhesion behaviors of various biological and engineered systems. However, precise control over the strong avidity‐based binding remains a significant chal
Externí odkaz:
https://doaj.org/article/4af1a67e58d74c08af7fc734c51953e7
Autor:
Woo-jin Jeong, Jiyoon Bu, Luke J. Kubiatowicz, Stephanie S. Chen, YoungSoo Kim, Seungpyo Hong
Publikováno v:
Nano Convergence, Vol 5, Iss 1, Pp 1-18 (2018)
Abstract Peptide–nanoparticle conjugates (PNCs) have recently emerged as a versatile tool for biomedical applications. Synergism between the two promising classes of materials allows enhanced control over their biological behaviors, overcoming intr
Externí odkaz:
https://doaj.org/article/3c55f0d9d480461a92591ed23563f49f
Autor:
Diana Dehaini, Luke J. Kubiatowicz, Ronnie H. Fang, Igor Landa, Liangfang Zhang, Grant R. Campbell, Jia Zhuang, Gang Zhang, Stephen A. Spector
Publikováno v:
Theranostics, vol 11, iss 18
Theranostics
Theranostics
HIV-1 is a major global health challenge. The development of an effective vaccine and a therapeutic cure are top priorities. The creation of vaccines that focus an antibody response toward a particular epitope of a protein has shown promise, but the
Autor:
Taehee Lee, Piper A. Rawding, Jiyoon Bu, Sunghee Hyun, Woosun Rou, Hongjae Jeon, Seokhyun Kim, Byungseok Lee, Luke J. Kubiatowicz, Dawon Kim, Seungpyo Hong, Hyuksoo Eun
Publikováno v:
Cancers; Volume 14; Issue 9; Pages: 2061
(1) Background: Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related death worldwide. Although various serum enzymes have been utilized for the diagnosis and prognosis of HCC, the currently available biomarkers lack the sensi
Autor:
Ashita Nair, Kara Mudd, Elizabeth W. Liu, Mari Iida, Woo Jin Jeong, Jiyoon Bu, Luke J. Kubiatowicz, Michael J. Poellmann, Deric L. Wheeler, Seungpyo Hong
Publikováno v:
Nano Lett
Upregulation of programmed death ligand 1 (PD-L1) allows cancer cells to evade antitumor immunity. Despite tremendous efforts in developing PD-1/PD-L1 immune checkpoint inhibitors (ICIs), clinical trials using such ICIs have shown inconsistent benefi
Autor:
Nishta Krishnan, Luke J. Kubiatowicz, Maya Holay, Jiarong Zhou, Ronnie H. Fang, Liangfang Zhang
Publikováno v:
Advanced drug delivery reviews. 185
Vaccines have been highly successful in the management of many diseases. However, there are still numerous illnesses, both infectious and noncommunicable, for which there are no clinically approved vaccine formulations. While there are unique difficu
Autor:
Jiyoon Bu, Woo-jin Jeong, Roya Jafari, Luke J. Kubiatowicz, Ashita Nair, Michael J. Poellmann, Rachel S. Hong, Elizabeth W. Liu, Randall H. Owen, Piper A. Rawding, Caroline M. Hopkins, DaWon Kim, Daniel J. George, Andrew J. Armstrong, Petr Král, Andrew Z. Wang, Justine Bruce, Tian Zhang, Randall J. Kimple, Seungpyo Hong
Publikováno v:
Biosensors and Bioelectronics. 213:114445
Despite its high potential, PD-L1 expressed by tumors has not been successfully utilized as a biomarker for estimating treatment responses to immunotherapy. Circulating tumor cells (CTCs) and tumor-derived exosomes that express PD-L1 can potentially
Autor:
Taehee Lee, Piper A. Rawding, Jiyoon Bu, Sung Hee Hyun, Woo Sun Rou, Kim Seok Hyun, Byung Seok Lee, Luke J. Kubiatowicz, DaWon Kim, Seungpyo Hong, Hyuk Soo Eun
Publikováno v:
Journal of Hepatology. 77:S921
Autor:
Andrew Z. Wang, Ashita Nair, Jiyoon Bu, Daniel J. George, Tian Zhang, Woo Jin Jeong, Andrew J. Armstrong, Luke J. Kubiatowicz, Marco Reyes-Martinez, Seungpyo Hong, Michael J. Poellmann
Publikováno v:
Biosensorsbioelectronics. 162
Sensitive detection of circulating tumor cells (CTCs) from patients' peripheral blood facilitates on-demand monitoring of tumor progression. However, clinically significant capture of renal cell carcinoma CTCs (RCC-CTCs) remains elusive due to their