Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Luke Gilbert"'
Autor:
S. John Liu, Tim Casey-Clyde, Nam Woo Cho, Jason Swinderman, Melike Pekmezci, Mark C. Dougherty, Kyla Foster, William C. Chen, Javier E. Villanueva-Meyer, Danielle L. Swaney, Harish N. Vasudevan, Abrar Choudhury, Joanna Pak, Jonathan D. Breshears, Ursula E. Lang, Charlotte D. Eaton, Kamir J. Hiam-Galvez, Erica Stevenson, Kuei-Ho Chen, Brian V. Lien, David Wu, Steve E. Braunstein, Penny K. Sneed, Stephen T. Magill, Daniel Lim, Michael W. McDermott, Mitchel S. Berger, Arie Perry, Nevan J. Krogan, Marlan R. Hansen, Matthew H. Spitzer, Luke Gilbert, Philip V. Theodosopoulos, David R. Raleigh
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Mechanisms specifying cancer cell states and response to therapy are incompletely understood. Here we show epigenetic reprogramming shapes the cellular landscape of schwannomas, the most common tumors of the peripheral nervous system. We fin
Externí odkaz:
https://doaj.org/article/6c3cb10a1a664ce0a55f363c96e7591d
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Context specificity confounds genetic analysis and prevents reproducible genome engineering. Here, the authors report a pan-CRISPR analysis of specificity in mammalian cells and identify ultra-compact sgRNA subsets for genome-scale screens.
Externí odkaz:
https://doaj.org/article/385d48492ec449398682d3f780f164a4
Autor:
Banurea, Rahmadhani, Purwanti, Eva, Syahrina, Maulia, Buysang, Luke Gilbert, Rachmad, Humam Rafi
Publikováno v:
Journal of Physics: Conference Series; 2024, Vol. 2733 Issue 1, p1-6, 6p
Autor:
S. John Liu, Tim Casey-Clyde, Nam Woo Cho, Jason Swinderman, Melike Pekmezci, Mark C. Dougherty, Kyla Foster, William C. Chen, Javier E. Villanueva-Meyer, Danielle L. Swaney, Harish N. Vasudevan, Abrar Choudhury, Jonathan D. Breshears, Ursula E. Lang, Charlotte D Eaton, Kamir J. Hiam-Galvez, Erica Stevenson, Kuei-Ho Chen, Brian V. Lien, David Wu, Steve E. Braunstein, Penny K. Sneed, Stephen T. Magill, Daniel Lim, Michael W. McDermott, Mitchel S. Berger, Arie Perry, Nevan J. Krogan, Marlon Hansen, Matthew H. Spitzer, Luke Gilbert, Philip V. Theodosopoulos, David R. Raleigh
SummaryCell state evolution underlies tumor development and response to therapy1, but mechanisms specifying cancer cell states and intratumor heterogeneity are incompletely understood. Schwannomas are the most common tumors of the peripheral nervous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc6f1b4185d7958479e36fb130929ae6
https://doi.org/10.1101/2022.12.23.521842
https://doi.org/10.1101/2022.12.23.521842
Autor:
Hanqin Li, Oriol Busquets, Yogendra Verma, Khaja Mohieddin Syed, Nitzan Kutnowski, Gabriella R. Pangilinan, Luke Gilbert, Helen Bateup, Donald C. Rio, Dirk Hockemeyer, Frank Soldner
Publikováno v:
eLife. 11
The recent development of prime editing (PE) genome engineering technologies has the potential to significantly simplify the generation of human pluripotent stem cell (hPSC)-based disease models. PE is a multicomponent editing system that uses a Cas9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10c7ab73708d340331b8ba13802a3294
https://doi.org/10.7554/elife.79208
https://doi.org/10.7554/elife.79208
Autor:
Farah M Barakat, Sophie Lewis, James Ashton, Luke Gilbert, Kouros Driscoll, Claire Barnes, Adebola Sholeye-Bolaji, Hang Phan, Guo Cheng, Rachel Haggarty, Akshay Batra, Nadeem A Afzal, R Mark Beattie, Sarah Ennis, Tracy Coelho
Publikováno v:
IBD.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e15e7384353ac98a04f7b30ad6836a72
https://doi.org/10.1136/flgastro-2022-bspghan.53
https://doi.org/10.1136/flgastro-2022-bspghan.53
Autor:
Marcela C. Briones Martin del Campo, Alex Lee, Max Horlbeck, Truc Dinh, Marta Roman-Moreno, Leanne Sayles, Bokyung Seong, Kimberly Stegmaier, Luke Gilbert, E. Alejandro Sweet-Cordero
Publikováno v:
Clinical Cancer Research. 28:B021-B021
While long non-coding RNAs (lncRNAs) are upregulated in many cancers, their role in pediatric cancers is unclear. Among pediatric cancers, Ewing sarcoma is unique in that these tumors show upregulation of a large, specific number of lncRNAs. To perfo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a241a76b4e56207a65534fc3e8176075
https://doi.org/10.1158/1557-3265.sarcomas22-b021
https://doi.org/10.1158/1557-3265.sarcomas22-b021
Autor:
Hao Shao, Shuhei Taguwa, Luke Gilbert, Arielle Shkedi, Sara Sannino, Christopher J. Guerriero, Zachary J. Gale-Day, Zapporah T. Young, Jeffrey L. Brodsky, Jonathan Weissman, Jason E. Gestwicki, Judith Frydman
Publikováno v:
Cell chemical biology. 29(8)
The potential of small molecules to localize within subcellular compartments is rarely explored. To probe this question, we measured the localization of Hsp70 inhibitors using fluorescence microscopy. We found that even closely related analogs had dr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d45ec1cf60ce50a889c13a138e8b8b17
https://pubmed.ncbi.nlm.nih.gov/35830852
https://pubmed.ncbi.nlm.nih.gov/35830852
Autor:
Arman Jahangiri, William Chen, Ankush Chandra, Alan Nguyen, Garima Yagnik, Jacob Weiss, Kayla J. Wolf, Jung-Ming G. Lin, Soeren Mueller, Jonathan Rick, Maxim Sidorov, Patrick Flanigan, W. Shawn Carbonell, Aaron Diaz, Luke Gilbert, Sanjay Kumar, Manish K. Aghi
Bevacizumab treatment of glioblastoma is limited by transient responses and acquired resistance. Because of the lengthy duration of treatment that can precede resistance in patients, in order to study changes underlying the evolution of bevacizumab r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40672d8339acc922d6d90ca4bd5848ce
https://doi.org/10.1101/272328
https://doi.org/10.1101/272328