Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Luke Frankiw"'
Autor:
Yuqian Wang, Zhe Wang, Juan Yang, Xiaobo Lei, Yisu Liu, Luke Frankiw, Jianwei Wang, Guideng Li
Publikováno v:
Advanced Science, Vol 11, Iss 13, Pp n/a-n/a (2024)
Abstract Deciphering cellular interactions is essential to both understand the mechanisms underlying a broad range of human diseases, but also to manipulate therapies targeting these diseases. Here, the formation of cell doublets resulting from speci
Externí odkaz:
https://doaj.org/article/f170345bbb53458abc990235c212b4ad
Autor:
Arun Singh, Begoña Comin-Anduix, Antoni Ribas, Beata Berent-Maoz, Theodore Scott Nowicki, Luke Frankiw, Cole Peters, Mignonette Macabali, Kiana Shammaie, Crystal Quiros, Paula Kaplan-Lefko, Ignacio Baselga Carretero
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 5 (2023)
Background The tumor antigen NY-ESO-1 has been shown to be an effective target for transgenic adoptive cell therapy (ACT) for the treatment of sarcoma and melanoma. However, despite frequent early clinical responses, many patients ultimately develop
Externí odkaz:
https://doaj.org/article/bdb959ecdff84f8485d422907659729b
Autor:
Yapeng Su, Melissa E. Ko, Hanjun Cheng, Ronghui Zhu, Min Xue, Jessica Wang, Jihoon W. Lee, Luke Frankiw, Alexander Xu, Stephanie Wong, Lidia Robert, Kaitlyn Takata, Dan Yuan, Yue Lu, Sui Huang, Antoni Ribas, Raphael Levine, Garry P. Nolan, Wei Wei, Sylvia K. Plevritis, Guideng Li, David Baltimore, James R. Heath
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Detailed understanding of how cancer cells transition from a drug sensitive to a tolerant state is lacking. Here, using single cell proteomic and metabolic data the authors uncover that isogenic BRAF mutant melanoma cells can take two distinct paths
Externí odkaz:
https://doaj.org/article/ef83fd0a40a640fbb4a0b6caefb26789
Autor:
Hongcheng Cheng, Yajing Qiu, Yue Xu, Li Chen, Kaili Ma, Mengyuan Tao, Luke Frankiw, Hongli Yin, Ermei Xie, Xiaoli Pan, Jing Du, Zhe Wang, Wenjie Zhu, Lu Chen, Lianjun Zhang, Guideng Li
Publikováno v:
Nature Metabolism. 5:314-330
The accumulation of acidic metabolic waste products within the tumor microenvironment inhibits effector functions of tumor-infiltrating lymphocytes (TILs). However, it remains unclear how an acidic environment affects T cell metabolism and differenti
Autor:
Luke Frankiw, Arun Singh, Cole Peters, Begoña Comin-Anduix, Beata Berent-Maoz, Mignonette Macabali, Kiana Shammaie, Crystal Quiros, Paula Kaplan-Lefko, Ignacio Baselga Carretero, Antoni Ribas, Theodore Scott Nowicki
Publikováno v:
Journal for immunotherapy of cancer, vol 11, iss 5
BackgroundThe tumor antigen NY-ESO-1 has been shown to be an effective target for transgenic adoptive cell therapy (ACT) for the treatment of sarcoma and melanoma. However, despite frequent early clinical responses, many patients ultimately develop p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e3975fbe7927d123fc9aeb35e4d3d63
https://escholarship.org/uc/item/7262q1p4
https://escholarship.org/uc/item/7262q1p4
Autor:
Luke, Frankiw, Guideng, Li
Publikováno v:
Cancer Letters. 548:215888
Autor:
Marco A. Marra, Rajiv Dixit, Mana Alshehri, Alexandra D. Rogers, Michael D. Blough, Stephen M. Robbins, Samuel Lawn, Lata Adnani, Jennifer A. Chan, Carol Schuurmans, Shiekh Tanveer Ahmad, Luke Frankiw, Wei Wu, Myra J. Chen, J. Gregory Cairncross
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Nature communications, vol 10, iss 1
Nature communications, vol 10, iss 1
Capicua (Cic) is a transcriptional repressor mutated in the brain cancer oligodendroglioma. Despite its cancer link, little is known of Cic’s function in the brain. We show that nuclear Cic expression is strongest in astrocytes and neurons but weak
Autor:
Jessica Wang, Luke Frankiw, Yapeng Su, Raphael D. Levine, Alexander M. Xu, Ronghui Zhu, Kaitlyn Takata, Wei Wei, Garry P. Nolan, Sylvia K. Plevritis, Guideng Li, Melissa E. Ko, Dan Yuan, David Baltimore, Jihoon W. Lee, Antoni Ribas, Stephanie Wong, Min Xue, Yue Lu, Hanjun Cheng, Sui Huang, James R. Heath, Lidia Robert
Publikováno v:
Nature communications, vol 11, iss 1
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
The determination of individual cell trajectories through a high-dimensional cell-state space is an outstanding challenge for understanding biological changes ranging from cellular differentiation to epigenetic responses of diseased cells upon druggi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a946ff3b1225b899db063486b4a7f72
https://escholarship.org/uc/item/4db017db
https://escholarship.org/uc/item/4db017db
Publikováno v:
RNA
At the heart of an innate immune response lies a tightly regulated gene expression program. This precise regulation is crucial because small changes can shift the balance from protective to destructive immunity. Here we identify a frequently used alt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3d700015130e03cb32486a242f3bb33
https://resolver.caltech.edu/CaltechAUTHORS:20191125-134707503
https://resolver.caltech.edu/CaltechAUTHORS:20191125-134707503
Autor:
Guideng Li, Sylvia K. Plevritis, Min Xue, David Baltimore, Jessica Wang, Alexander M. Xu, Stephanie Wong, Antoni Ribas, James R. Heath, Kaitlyn Takata, Garry P. Nolan, Jihoon W. Lee, Sui Huang, Lidia Robert, Melissa E. Ko, Wei Wei, Yapeng Su, Raphael D. Levine, Luke Frankiw, Ronghui Zhu, Hanjun Cheng
The determination of individual cell trajectories through a high-dimensional cell-state space is an outstanding challenge, with relevance towards understanding biological changes ranging from cellular differentiation to epigenetic (adaptive) response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14d16202699313af795ed38046d38cc3
https://doi.org/10.1101/767988
https://doi.org/10.1101/767988