Výsledky vyhledávání - "Luke Boothman"

Maintenance of murine platelet homeostasis by the kinase Csk and phosphatase CD148

Autor: Arthur Weiss, Louise Tee, Joao Correia, Zoltan Nagy, Mitchell J. Geer, Marijke J.E. Kuijpers, Silke Heising, Bibian M. E. Tullemans, Luke Boothman, Jun Mori, Paul Harrison, Johanna P. van Geffen, Rashid Hafidh Rashid Al Ghaithi, Christopher W Smith, Yotis A. Senis, Johan W. M. Heemskerk, Gavin E. Jarvis, Alexander Tarakhovsky, Giada Di Nunzio, Alexandra Mazharian

Publikováno v: Blood, 131(10), 1122-1144. The American Society of Hematology

Src family kinases (SFKs) coordinate the initiating and propagating activation signals in platelets, but it remains unclear how they are regulated. Here, we show that ablation of C-terminal Src kinase (Csk) and receptor-like protein tyrosine-phosphat

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