Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Luke A. Beggs"'
Autor:
Ean G Phillips, Luke A Beggs, Fan Ye, Christine F Conover, Darren T Beck, Dana M Otzel, Payal Ghosh, Anna C F Bassit, Stephen E Borst, Joshua F Yarrow
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0194440 (2018)
Sclerostin is a circulating osteocyte-derived glycoprotein that negatively regulates Wnt-signaling after binding the LRP5/LRP6 co-receptors. Pharmacologic sclerostin inhibition produces bone anabolic effects after spinal cord injury (SCI), however, t
Externí odkaz:
https://doaj.org/article/1b9b5703cd45433a8670c7492f56764a
Autor:
Joshua F Yarrow, Luke A Beggs, Christine F Conover, Sean C McCoy, Darren T Beck, Stephen E Borst
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e47315 (2012)
Several endocrine factors, including sex-steroid hormones are known to influence adiponectin secretion. Our purpose was to evaluate the influence of testosterone and of the synthetic non-aromatizable/non-5α reducible androgen 17β-hydroxyestra-4,9,1
Externí odkaz:
https://doaj.org/article/65f8eb02874f43d7ac7bf395f5f0a066
Autor:
Joshua F. Yarrow, Luke A. Beggs, Stephen E. Borst, Michael D. Roberts, Wesley C. Kephart, Alexander Balaez, Christine F. Conover, Christopher B. Mobley, Petey W. Mumford, Darren T. Beck
Publikováno v:
Andrologia. 48:1055-1065
Summary The effects of testosterone (TEST) treatment on markers of skeletal muscle ribosome biogenesis in vitro and in vivo were examined. C2C12 myotubes were treated with 100 nm TEST for short-term (24-h) and longer-term (96-h) treatments. Moreover,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6730dd504e9e26a8bceba2f3816af4a
https://doi.org/10.1111/and.12539
https://doi.org/10.1111/and.12539
Autor:
Anna C F Bassit, Fan Ye, Dana M. Otzel, Luke A. Beggs, Payal Ghosh, Stephen E. Borst, Darren T. Beck, Joshua F. Yarrow, Ean G. Phillips, Christine F. Conover
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 3, p e0194440 (2018)
PLoS ONE, Vol 13, Iss 3, p e0194440 (2018)
Sclerostin is a circulating osteocyte-derived glycoprotein that negatively regulates Wnt-signaling after binding the LRP5/LRP6 co-receptors. Pharmacologic sclerostin inhibition produces bone anabolic effects after spinal cord injury (SCI), however, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bb720ddbe8c121c6b967b0625ef63b0
http://europepmc.org/articles/PMC5868788
http://europepmc.org/articles/PMC5868788
Autor:
Darren T. Beck, Alyssa A. Williams, Joshua F. Yarrow, Ean G. Phillips, Payal Ghosh, Julie R Miller, JIgnacio Aguirre, Stephen E. Borst, Christine F. Conover, Thomas J. Wronski, Alexander Balaez, Nigel Zheng, Fan Ye, Prodip Bose, Luke A. Beggs
Publikováno v:
Journal of Bone and Mineral Research. 30:681-689
Spinal cord injury (SCI) results in rapid and extensive sublesional bone loss. Sclerostin, an osteocyte-derived glycoprotein that negatively regulates intraskeletal Wnt signaling, is elevated after SCI and may represent a mechanism underlying this ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e0c157e6555798495d464bff2a7821b
https://doi.org/10.1002/jbmr.2396
https://doi.org/10.1002/jbmr.2396
Autor:
Stephen E. Borst, Alexander Balaez, Darren T. Beck, Dana M. Otzel, Prodip Bose, Luke A. Beggs, Christine F. Conover, Thomas J. Wronski, Joshua F. Yarrow, Julie R Miller, Bryan P. Conrad, Kathleen G Neuville, J. Ignacio Aguirre, Alyssa A. Williams, Chris M. Gregory, Sarah M Combs, Fan Ye
Publikováno v:
Journal of Neurotrauma. 31:834-845
Androgen administration protects against musculoskeletal deficits in models of sex-steroid deficiency and injury/disuse. It remains unknown, however, whether testosterone prevents bone loss accompanying spinal cord injury (SCI), a condition that resu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1612df65a0f6d06ea2f53dd9d0959a42
https://doi.org/10.1089/neu.2013.3155
https://doi.org/10.1089/neu.2013.3155
Autor:
Luke A. Beggs, Stephen E. Borst, Christine F. Conover, Joshua F. Yarrow, Bruce A. Goldberger, Darren T. Beck
Publikováno v:
Steroids
Enzyme immunoassays (EIA) are commonly utilized for the evaluation of androgens in biological fluids; however, careful consideration must be given to cross-reactivity with other endogenous sex-steroid hormones. Our purpose was to determine the validi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40cce8f644c69421bf1ce9b7253dba18
https://doi.org/10.1016/j.steroids.2013.08.013
https://doi.org/10.1016/j.steroids.2013.08.013
Autor:
Luke A. Beggs, C. Brooks Mobley, Wesley C. Kephart, Michael D. Roberts, Darren T. Beck, Stephen E. Borst, Alexander Balaez, Dana M. Otzel, Christine F. Conover, Joshua F. Yarrow, Petey W. Mumford, A. Maleah Holland
Publikováno v:
Journal of applied physiology (Bethesda, Md. : 1985). 121(3)
The influence of the aromatase enzyme on the chronic fat-sparing effects of testosterone requires further elucidation. Our purpose was to determine whether chronic anastrozole (AN, an aromatase inhibitor) treatment alters testosterone-mediated lipoly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c945d49cd97e5a4fbc78d7f49da598eb
https://pubmed.ncbi.nlm.nih.gov/27539493
https://pubmed.ncbi.nlm.nih.gov/27539493
Autor:
Stephen E. Borst, Jonathan J. Shuster, Matthew Morrow, Christine F. Conover, John R. Meuleman, Joshua F. Yarrow, Luke A. Beggs, Baiming Zou, Darren T. Beck
Testosterone (T) stimulates erythropoiesis and regulates iron homeostasis. However, it remains unknown whether the (type II) 5α-reduction of T to dihydrotestosterone (DHT) mediates these androgenic effects, as it does in some other tissues. Our purp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcf9eb415f27e0a1d9b34af9085c47e5
https://europepmc.org/articles/PMC4154071/
https://europepmc.org/articles/PMC4154071/
Autor:
Darren T, Beck, Joshua F, Yarrow, Luke A, Beggs, Dana M, Otzel, Fan, Ye, Christine F, Conover, Julie R, Miller, Alexander, Balaez, Sarah M, Combs, Alicia M, Leeper, Alyssa A, Williams, Stephanie A, Lachacz, Nigel, Zheng, Thomas J, Wronski, Stephen E, Borst
Publikováno v:
J Bone Miner Res
The influence of the aromatase enzyme in androgen-induced bone maintenance after skeletal maturity remains somewhat unclear. Our purpose was to determine whether aromatase activity is essential to androgen-induced bone maintenance. Ten-month-old male
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ff543d2dec22d5083c2566c69c748296
https://pubmed.ncbi.nlm.nih.gov/24764121
https://pubmed.ncbi.nlm.nih.gov/24764121