Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Luke A Weyrauch"'
1
Akademický článek
Estrogen receptor-α in female skeletal muscle is not required for regulation of muscle insulin sensitivity and mitochondrial regulation
Autor: Melissa R. Iñigo, Adam J. Amorese, Michael D. Tarpey, Nicholas P. Balestrieri, Keith G. Jones, Daniel J. Patteson, Kathryn C. Jackson, Maria.J. Torres, Chien-Te Lin, Cody D. Smith, Timothy D. Heden, Shawna L. McMillin, Luke A. Weyrauch, Erin C. Stanley, Cameron A. Schmidt, Brita B. Kilburg-Basnyat, Sky W. Reece, Christine E. Psaltis, Leslie A. Leinwand, Katsu Funai, Joseph M. McClung, Kymberly M. Gowdy, Carol A. Witczak, Dawn A. Lowe, P. Darrell Neufer, Espen E. Spangenburg
Publikováno v: Molecular Metabolism, Vol 34, Iss , Pp 1-15 (2020)
Objective: Estrogen receptor-α (ERα) is a nuclear receptor family member thought to substantially contribute to the metabolic regulation of skeletal muscle. However, previous mouse models utilized to assess the necessity of ERα signaling in skelet
Externí odkaz: https://doaj.org/article/cef6092a71cd44739e7411b85eb621c4
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2
Akademický článek
Muscle-Specific Ablation of Glucose Transporter 1 (GLUT1) Does Not Impair Basal or Overload-Stimulated Skeletal Muscle Glucose Uptake
Autor: Shawna L. McMillin, Parker L. Evans, William M. Taylor, Luke A. Weyrauch, Tyler J. Sermersheim, Steven S. Welc, Monique R. Heitmeier, Richard C. Hresko, Paul W. Hruz, Francoise Koumanov, Geoffrey D. Holman, E. Dale Abel, Carol A. Witczak
Publikováno v: Biomolecules, Vol 12, Iss 12, p 1734 (2022)
Glucose transporter 1 (GLUT1) is believed to solely mediate basal (insulin-independent) glucose uptake in skeletal muscle; yet recent work has demonstrated that mechanical overload, a model of resistance exercise training, increases muscle GLUT1 leve
Externí odkaz: https://doaj.org/article/147a73ac6c2d4bab8a2344c5e3fe0de0
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3
Genetically increasing flux through β-oxidation in skeletal muscle increases mitochondrial reductive stress and glucose intolerance
Autor: Cody D. Smith, Cheryl A.S. Smith, Shawna L. McMillin, P. Darrell Neufer, Luke A. Weyrauch, Carol A. Witczak, Chein-Te Lin, Irwin J. Kurland, Cameron A. Schmidt
Publikováno v: Am J Physiol Endocrinol Metab
Elevated mitochondrial hydrogen peroxide (H(2)O(2)) emission and an oxidative shift in cytosolic redox environment have been linked to high-fat-diet-induced insulin resistance in skeletal muscle. To test specifically whether increased flux through mi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa8fa8622d77fcd786f9ff1501e4fa35
https://doi.org/10.1152/ajpendo.00010.2021
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5
Influence of Maternal Exercise on Glucose and Lipid Metabolism in Offspring Stem Cells: ENHANCED by Mom
Autor: Alec Chaves, Luke A Weyrauch, Donghai Zheng, Ericka M Biagioni, Polina M Krassovskaia, Breanna L Davidson, Nicholas T Broskey, Kristen E Boyle, Linda E May, Joseph A Houmard
Publikováno v: The Journal of clinical endocrinology and metabolism. 107(8)
Context Recent preclinical data suggest exercise during pregnancy can improve the metabolic phenotype not only of the mother, but of the developing offspring as well. However, investigations in human offspring are lacking. Objective To characterize t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6767376339934c67f7acf3d04f184427
https://pubmed.ncbi.nlm.nih.gov/35511592
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6
Insulin Resistance Is Not Sustained Following Denervation in Glycolytic Skeletal Muscle
Autor: Carol A. Witczak, Shawna L. McMillin, Jeffrey J. Brault, Luke A. Weyrauch, Erin C. Stanley, Barbara B. Kahn
Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 4913, p 4913 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 9
Denervation rapidly induces insulin resistance (i.e., impairments in insulin-stimulated glucose uptake and signaling proteins) in skeletal muscle. Surprisingly, whether this metabolic derangement is long-lasting is presently not clear. The main goal
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02ced5fba25fa0d8d9883dcf476f5164
https://www.mdpi.com/1422-0067/22/9/4913
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7
Regulation of Skeletal Muscle Glucose Transport and Glucose Metabolism by Exercise Training
Autor: Luke A. Weyrauch, Shawna L. McMillin, Parker L. Evans, Carol A. Witczak
Publikováno v: Nutrients
Nutrients, Vol 11, Iss 10, p 2432 (2019)
Aerobic exercise training and resistance exercise training are both well-known for their ability to improve human health; especially in individuals with type 2 diabetes. However, there are critical differences between these two main forms of exercise
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ec5a574def34994262f22f530a593d3
https://pubmed.ncbi.nlm.nih.gov/31614762
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8
Insulin Resistance Does Not Impair Mechanical Overload-Stimulated Glucose Uptake, but Does Alter the Metabolic Fate of Glucose in Mouse Muscle
Autor: Carol A. Witczak, Shawna McMillin, Luke A. Weyrauch
Publikováno v: International Journal of Molecular Sciences, Vol 21, Iss 4715, p 4715 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 13
Skeletal muscle glucose uptake and glucose metabolism are impaired in insulin resistance. Mechanical overload stimulates glucose uptake into insulin-resistant muscle
yet the mechanisms underlying this beneficial effect remain poorly understood.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::979e752f18942a53d99d20ae77e2fe4b
https://doi.org/10.3390/ijms21134715
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