Calibrating a network meta-analysis of diabetes trials of sodium glucose cotransporter 2 inhibitors, glucagon-like peptide-1 receptor analogues and dipeptidyl peptidase-4 inhibitors to a representative routine population: a systematic review protocol

Autor: Naveed Sattar, Sofia Dias, Sarah Wild, Laurie A Tomlinson, David McAllister, Amanda I Adler, Nicky Welton, Lili Wei, Katherine Hughes, Peter Hanlon, Elaine Butterly, Jim Lewsey, John Petrie, Robert Lindsay, Saleh A M Almazam, Khalid Alsallumi, Luke A K Blackbourn, Stuart McGurnaghan, David Phillippo

Publikováno v: BMJ Open, Vol 12, Iss 10 (2022)

Introduction Participants in randomised controlled trials (trials) are generally younger and healthier than many individuals encountered in clinical practice. Consequently, the applicability of trial findings is often uncertain. To address this, resu

Externí odkaz: https://doaj.org/article/946d5f6599ce403f8514b5c0facf5297

Effect of serum sample storage temperature on metabolomic and proteomic biomarkers

Autor: Erkka Valo, Marco Colombo, Niina Sandholm, Stuart J. McGurnaghan, Luke A. K. Blackbourn, David B. Dunger, Paul M. McKeigue, Carol Forsblom, Per-Henrik Groop, Helen M. Colhoun, Charles Turner, R. Neil Dalton

Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)

Abstract Prospective biomarker studies can be used to identify biomarkers predictive of disease onset. However, if serum biomarkers are measured years after their collection, the storage conditions might affect analyte concentrations. Few data exists

Externí odkaz: https://doaj.org/article/b58b42738bbf4bd599e01cbd8dcbc87c

Calibrating a network meta-analysis of diabetes trials of sodium glucose cotransporter 2 inhibitors, glucagon-like peptide-1 receptor analogues and dipeptidyl peptidase-4 inhibitors to a representative routine population: a systematic review protocol

Autor: Elaine Butterly, Lili Wei, Amanda I Adler, Saleh A M Almazam, Khalid Alsallumi, Luke A K Blackbourn, Sofia Dias, Peter Hanlon, Katherine Hughes, Jim Lewsey, Robert Lindsay, Stuart McGurnaghan, John Petrie, David Phillippo, Naveed Sattar, Laurie A Tomlinson, Nicky Welton, Sarah Wild, David McAllister

Publikováno v: Butterly, E, Wei, L, Adler, A I, Almazam, S A, Alsallumi, K, Blackbourn, L, Dias, S, Peter, H, Hughes, K A, Lewsey, J, Lindsay, R S, McGurnaghan, S, Petrie, J R, Phillippo, D, Sattar, N A, Tomlinson, L, Welton, N J, Wild, S H & McAllister, D A 2022, ' Calibrating a network meta-analysis of diabetes trials of sodium glucose co-transporter 2 inhibitors, glucagon-like peptide-1 receptor analogues and dipeptidyl peptidase-4 inhibitors to a representative routine population : a systematic review protocol ', BMJ Open, vol. 12, no. 10, 066491, pp. e066491 . https://doi.org/10.1136/bmjopen-2022-066491

IntroductionParticipants in randomised controlled trials (trials) are generally younger and healthier than many individuals encountered in clinical practice. Consequently, the applicability of trial findings is often uncertain. To address this, resul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0969065cc95310742d6794321e8173e1
https://pubmed.ncbi.nlm.nih.gov/36302574

The association of polypharmacy and high-risk drug classes with adverse health outcomes in the Scottish population with type 1 diabetes

Autor: Rory J. McCrimmon, John A. McKnight, Naveed Sattar, Anita Jeyam, Joseph E. O'Reilly, Thomas M Caparrotta, Graham P. Leese, Brian Kennon, Sarah H. Wild, Hohn Andreas, Robert S. Lindsay, Helen M. Colhoun, Paul M. McKeigue, Stuart J. McGurnaghan, Luke A K Blackbourn

Publikováno v: Diabetologia
Colhoun, H M 2021, ' The association of polypharmacy and high-risk drug classes with adverse health outcomes in the Scottish population with type 1 diabetes ', Diabetologia, vol. 64, no. 6, pp. 1309-1319 . https://doi.org/10.1007/s00125-021-05394-7, https://doi.org/10.1007/s00125-021-05394-7, https://doi.org/10.1007/s00125-021-05394-7

Aims/hypothesis The aim of this work was to map the number of prescribed drugs over age, sex and area-based socioeconomic deprivation, and to examine the association between the number of drugs and particular high-risk drug classes with adverse healt

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89b22fe7332bf78f9b04506476b1e5de
http://europepmc.org/articles/PMC8099818

Flash monitor initiation is associated with improvements in HbA1c levels and DKA rates among people with type 1 diabetes in Scotland : a retrospective nationwide observational study

Autor: Fraser W. Gibb, Naveed Sattar, Rory J. McCrimmon, Joseph E. O'Reilly, Graham P. Leese, Brian Kennon, Sam Philip, John A. McKnight, Hohn Andreas, Thomas M Caparrotta, Luke A K Blackbourn, Stuart J. McGurnaghan, Sara Hatam, Helen M. Colhoun, Paul M. McKeigue, Anita Jeyam

Publikováno v: Jeyam, A, Gibb, F W, McKnight, J A, O'Reilly, J, Caparrotta, T, Höhn, A, McGurnaghan, S, Blackbourn, L, Hatam, S, Kennon, B, McCrimmon, R J, Leese, G P, Philip, S, Sattar, N A, McKeigue, P M, Colhoun, H M & Scottish Diabetes Research Network Epidemiology Group, O B 2021, ' Flash monitor initiation is associated with improvements in HbA1c levels and DKA rates among people with Type 1 Diabetes in Scotland, a retrospective nationwide observational study. ', Diabetologia . https://doi.org/10.1007/s00125-021-05578-1
Diabetologia

Aims/hypothesis We assessed the real-world effect of flash monitor (FM) usage on HbA1c levels and diabetic ketoacidosis (DKA) and severe hospitalised hypoglycaemia (SHH) rates among people with type 1 diabetes in Scotland and across sociodemographic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee91350ab18f2a44496b3cfc7a7c0726
https://hdl.handle.net/10023/24158