Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Luke A Greenhough"'
Autor:
Peter D. Craggs, Faith Mazani, Gabriella Clarke, Carl Haslam, Bhumika Karamshi, Paul Rowland, Sam Rowe, Luke A Greenhough, Ryan P. Bingham, Cassie Messenger, Alexander N Phillipou
Publikováno v:
SLAS discovery : advancing life sciences RD. 26(5)
The predominant assay detection methodologies used for enzyme inhibitor identification during early-stage drug discovery are fluorescence-based. Each fluorophore has a characteristic fluorescence decay, known as the fluorescence lifetime, that occurs
Autor:
Cassie Messenger, Laurie J. Gordon, Simon C. C. Lucas, Aaron T. Cheng, Kelly M Gatfield, John P. Evans, Emma J. Jones, Mahnoor Mahmood, Charles S. Lay, Charlotte E. Carver, Douglas Sammon, Antonia J. Lewis, Alexander N Phillipou, Syandan Chakraborty, Luke A Greenhough, Peter D. Craggs, David J Brierley
Publikováno v:
SLAS discovery : advancing life sciences RD. 25(2)
Malfunctions in the basic epigenetic mechanisms such as histone modifications, DNA methylation, and chromatin remodeling are implicated in a number of cancers and immunological and neurodegenerative conditions. Within GlaxoSmithKline (GSK) we have ut