Výsledky vyhledávání - "Luke A, Granger"

Akademický článek

Increasing the CpG dinucleotide abundance in the HIV-1 genomic RNA inhibits viral replication

Autor: Irati Antzin-Anduetza, Charlotte Mahiet, Luke A. Granger, Charlotte Odendall, Chad M. Swanson

Publikováno v: Retrovirology, Vol 14, Iss 1, Pp 1-18 (2017)

Abstract Background The human immunodeficiency virus type 1 (HIV-1) structural protein Gag is necessary and sufficient to form viral particles. In addition to encoding the amino acid sequence for Gag, the underlying RNA sequence could encode cis-acti

Externí odkaz: https://doaj.org/article/5987dc7c27db4d8eabc1a63fad2684d1

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Broadly neutralizing antibody responses in the longitudinal primary HIV-1 infection Short Pulse Anti-Retroviral Therapy at Seroconversion cohort

Autor: John Frater, Luke A. Granger, Jonathan Weber, Giuseppe Tambussi, David A. Cooper, José M. Miró, Martin Fisher, Gita Ramjee, Isabella Huettner, Julie Fox, Abdel Babiker, Sarah Fidler, Pontiano Kaleebu, Katie J. Doores, Rodney E. Phillips, Franka Debeljak, Mauro Schechter

Publikováno v: AIDS (London, England)

OBJECTIVE: Development of immunogens that elicit an anti-HIV-1 broadly neutralizing antibody (bnAb) response will be a key step in the development of an effective HIV-1 vaccine. Although HIV-1 bnAb epitopes have been identified and mechanisms of acti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0199d9b820b892fbab475f16c31cb00
http://hdl.handle.net/10044/1/101938

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Akademický článek

Retromer regulates HIV-1 envelope glycoprotein trafficking and incorporation into virions.

Autor: Elisabetta Groppelli, Alice C Len, Luke A Granger, Clare Jolly

Publikováno v: PLoS Pathogens, Vol 10, Iss 10, p e1004518 (2014)

The envelope glycoprotein (Env) of the Human Immunodeficiency Virus Type-1 (HIV-1) is a critical determinant of viral infectivity, tropism and is the main target for humoral immunity; however, little is known about the cellular machinery that directs

Externí odkaz: https://doaj.org/article/d1df4b54f9a94f9cb418dc85d9ce5cd8

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Increasing the CpG dinucleotide abundance in the HIV-1 genomic RNA inhibits viral replication

Autor: Charlotte Odendall, Irati Antzin-Anduetza, Chad M. Swanson, Charlotte Mahiet, Luke A. Granger

Publikováno v: Antzin-Anduetza, I, Mahiet, C, Granger, L A, Odendall, C & Swanson, C M 2017, ' Increasing the CpG dinucleotide abundance in the HIV-1 genomic RNA inhibits viral replication ', Retrovirology, vol. 14, 49 . https://doi.org/10.1186/s12977-017-0374-1
Retrovirology
Retrovirology, Vol 14, Iss 1, Pp 1-18 (2017)

Background The human immunodeficiency virus type 1 (HIV-1) structural protein Gag is necessary and sufficient to form viral particles. In addition to encoding the amino acid sequence for Gag, the underlying RNA sequence could encode cis-acting elemen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::992766472f740105db8322d281c537c7
https://kclpure.kcl.ac.uk/en/publications/b30f5f60-7872-489d-91be-ee816728b9ba

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Unravelling the Molecular Basis of High Affinity Nanobodies against HIV p24: In Vitro Functional, Structural, and in Silico Insights

Autor: Eleanor R, Gray, Jennifer C, Brookes, Christophe, Caillat, Valérian, Turbé, Benjamin L J, Webb, Luke A, Granger, Benjamin S, Miller, Laura E, McCoy, Mohamed, El Khattabi, C Theo, Verrips, Robin A, Weiss, Dorothy M, Duffy, Winfried, Weissenhorn, Rachel A, McKendry

Publikováno v: ACS Infectious Diseases
ACS Infectious Diseases, 2017, ⟨10.1021/acsinfecdis.6b00189⟩
ACS Infectious Diseases, American Chemical Society, 2017, ⟨10.1021/acsinfecdis.6b00189⟩

International audience; Preventing the spread of infectious diseases remains an urgent priority worldwide, and this is driving the development of advanced nanotechnology to diagnose infections at the point of care. Herein, we report the creation of a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::b5630792871cceb574d2be8bcb941599
https://hal.univ-grenoble-alpes.fr/hal-01561577

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Retromer Regulates HIV-1 Envelope Glycoprotein Trafficking and Incorporation into Virions

Autor: Alice C. L. Len, Luke A. Granger, Clare Jolly, Elisabetta Groppelli

Publikováno v: PLoS Pathogens
PLoS Pathogens, Vol 10, Iss 10, p e1004518 (2014)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29d72ba2703464a18c6b75729204932e
https://doi.org/10.1371/journal.ppat.1004518

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