P2 - VARIANT PROFILING IN PEDIATRIC CHRONIC MYELOID LEUKEMIA

Autor: Behrens, Yvonne Lisa, Göhring, Gudrun, Gaschler, Laura, Nienhold, Ronny, Reinkens, Thea, Schirmer, Elke, Lukat, Sabine, Knöß, Sabine, Strasser, Renate, Sembill, Stephanie, Wotschofsky, Zofia, Suttorp, Meinolf, Krumbholz, Manuela, Schlegelberger, Brigitte, Metzler, Markus, Karow, Axel

Publikováno v: In EJC Paediatric Oncology December 2023 2 Supplement 1

A new semisynthetic cardenolide analog 3β-[2-(1-amantadine)- 1-on-ethylamine]-digitoxigenin (AMANTADIG) affects G2/M cell cycle arrest and miRNA expression profiles and enhances proapoptotic survivin-2B expression in renal cell carcinoma cell lines.

Autor: Nolte E; Department of Urology, University Hospital Erlangen, Erlangen, Germany., Wach S; Department of Urology, University Hospital Erlangen, Erlangen, Germany., Silva IT; Department of Pharmaceutical Sciences, Universidade Federal de Santa Catarina, Florianópolis, Brazil.; Department of Pharmacy, Federal University of Minas Gerais, Belo Horizonte, Brazil., Lukat S; Department of Urology, University Hospital Erlangen, Erlangen, Germany., Ekici AB; Institute of Human Genetics, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany., Munkert J; Department of Biology, Chair of Pharmaceutical Biology, Friedrich-Alexander-University Erlangen-Nürnberg, Erlangen, Germany., Müller-Uri F; Department of Biology, Chair of Pharmaceutical Biology, Friedrich-Alexander-University Erlangen-Nürnberg, Erlangen, Germany., Kreis W; Department of Biology, Chair of Pharmaceutical Biology, Friedrich-Alexander-University Erlangen-Nürnberg, Erlangen, Germany., Oliveira Simões CM; Department of Pharmaceutical Sciences, Universidade Federal de Santa Catarina, Florianópolis, Brazil., Vera J; Laboratory of Systems Tumor Immunology, Department of Dermatology, University Hospital Erlangen, Friedrich-Alexander-University Erlangen-Nürnberg, Erlangen, Germany., Wullich B; Department of Urology, University Hospital Erlangen, Erlangen, Germany., Taubert H; Department of Urology, University Hospital Erlangen, Erlangen, Germany., Lai X; Laboratory of Systems Tumor Immunology, Department of Dermatology, University Hospital Erlangen, Friedrich-Alexander-University Erlangen-Nürnberg, Erlangen, Germany.

Publikováno v: Oncotarget [Oncotarget] 2017 Feb 14; Vol. 8 (7), pp. 11676-11691.