Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Lukasz Przybyl"'
Autor:
Anna Kotowska-Zimmer, Lukasz Przybyl, Marianna Pewinska, Joanna Suszynska-Zajczyk, Dorota Wronka, Maciej Figiel, Marta Olejniczak
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 28, Iss , Pp 702-715 (2022)
Among the many proposed therapeutic strategies for Huntington's disease (HD), allele-selective therapies are the most desirable but also the most challenging. RNA interference (RNAi) tools that target CAG repeats selectively reduce the mutant hunting
Externí odkaz:
https://doaj.org/article/f010f7696caf4052a9f3bf981d0f4f3f
Autor:
Aleksandra Majchrzak-Celińska, Julia O. Misiorek, Nastassia Kruhlenia, Lukasz Przybyl, Robert Kleszcz, Katarzyna Rolle, Violetta Krajka-Kuźniak
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-18 (2021)
Abstract Background Glioblastoma (GBM) is the deadliest and the most common primary brain tumor in adults. The invasiveness and proliferation of GBM cells can be decreased through the inhibition of Wnt/β-catenin pathway. In this regard, celecoxib is
Externí odkaz:
https://doaj.org/article/a2cc76bcb11e4d9489f8b73501b6fd1f
Autor:
Nadine Haase, Julianna Rugor, Lukasz Przybyl, Fatimunnisa Qadri, Dominik N Müller, Ralf Dechend
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e93743 (2014)
Relaxin is a corpus-luteum produced protein hormone with vasodilatatory, anti-fibrotic, and angiogenic properties that are opposite to angiotensin (Ang) II. We investigated whether or not relaxin ameliorates Ang II-induced target-organ damage. We use
Externí odkaz:
https://doaj.org/article/ed96280a03b74b10bf01a59306c3446f
Autor:
Gregory Kroliczak, Lukasz Przybylski
Publikováno v:
Humanities & Social Sciences Communications, Vol 11, Iss 1, Pp 1-11 (2024)
Abstract The impact of handedness on neural substrates of common tool processing and tool use skills as proxies to the mechanisms underlying modern reciprocal relationships among humans and their brains, the tools they create and use, and technologie
Externí odkaz:
https://doaj.org/article/24a9f414c7ec4954a6e7b919a516e28a
Autor:
Marianna Pewinska, Maciej Figiel, Lukasz Przybyl, Dorota Wronka, Anna Kotowska-Zimmer, Marta Olejniczak, Joanna Suszynska-Zajczyk
Publikováno v:
I: Experimental therapeutics – preclinical.
Background Among many proposed therapeutic strategies for Huntington’s disease (HD), allele-selective therapies are the most desirable and the most challenging at the same time. We have previously demonstrated that RNA interference (RNAi) tools tha
Autor:
Magdalena Jazurek-Ciesiolka, Pawel M. Switonski, Maciej Figiel, Agnieszka Fiszer, Paula Sobieszczanska, Dorota Wronka, Lukasz Przybyl, Joanna Suszynska-Zajczyk, Adam Ciesiolka, Grzegorz Figura, Magdalena Wozna-Wysocka, Julia O. Misiorek, Wlodzimierz J. Krzyzosiak
Publikováno v:
B: Models for HD.
Background Experiments with HD mouse models allow for insight into detailed molecular pathways disrupted in the course of disease development. New aspects of HD pathology need to be determined to bring additional targets and hints for therapeutic app
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 1561, p 1561 (2021)
International Journal of Molecular Sciences, Vol 22, Iss 1561, p 1561 (2021)
Among the main challenges in further advancing therapeutic strategies for Huntington’s disease (HD) is the development of biomarkers which must be applied to assess the efficiency of the treatment. HD is a dreadful neurodegenerative disorder which
Autor:
Katarzyna Rolle, Lukasz Przybyl, Violetta Krajka-Kuźniak, Julia O. Misiorek, Robert Kleszcz, Nastassia Kruhlenia, Aleksandra Majchrzak-Celińska
Publikováno v:
BMC Cancer
BMC Cancer, Vol 21, Iss 1, Pp 1-18 (2021)
BMC Cancer, Vol 21, Iss 1, Pp 1-18 (2021)
Background Glioblastoma (GBM) is the deadliest and the most common primary brain tumor in adults. The invasiveness and proliferation of GBM cells can be decreased through the inhibition of Wnt/β-catenin pathway. In this regard, celecoxib is a promis
Publikováno v:
Arthropod Systematics & Phylogeny, Vol 81, Iss , Pp 371-394 (2023)
The subgenus Parapisa of the genus Apisa is reviewed based on the examination of 104 specimens. Apisa (P.) cinereocostata and A. (P.) subargentea are redescribed and their intraspecific variation is analysed in detail. A new species A. (P.) asipa, si
Externí odkaz:
https://doaj.org/article/a9bb6b1595dc4c0999cb4a0c9c940d6d
Autor:
Ivo Bendix, Lukasz Przybyl, Tarek Ibrahim, Anne Cathrine Staff, Nadine Haase, Julianna Rugor, Michaela Golic, Meray Serdar, Ralf Dechend, Gerd Wallukat, Babette LaMarca, Florian Herse, Thomas Hünig, Ursula Felderhoff-Müser, Dominik N. Müller, Friedrich C. Luft
Publikováno v:
Hypertension. 65:1298-1306
Preeclampsia is a multisystemic syndrome during pregnancy that is often associated with intrauterine growth retardation. Immunologic dysregulation, involving T cells, is implicated in the pathogenesis. The aim of this study was to evaluate the effect