Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Lukasz Opalinski"'
Autor:
Magdalena Gebert, Sylwia Bartoszewska, Lukasz Opalinski, James F. Collawn, Rafał Bartoszewski
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-20 (2023)
Abstract The unfolded protein response is a survival signaling pathway that is induced during various types of ER stress. Here, we determine IRE1’s role in miRNA regulation during ER stress. During induction of ER stress in human bronchial epitheli
Externí odkaz:
https://doaj.org/article/61931b810a8b4da1bd32d89864aa77c0
Autor:
Aleksandra Gedaj, Dominika Zukowska, Natalia Porebska, Marta Pozniak, Mateusz Krzyscik, Aleksandra Czyrek, Daniel Krowarsch, Malgorzata Zakrzewska, Jacek Otlewski, Lukasz Opalinski
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-12 (2023)
Abstract Fibroblast growth factors (FGFs) and their receptors (FGFRs) constitute complex signaling hubs that are crucial for the development and homeostasis of the human body. Most of FGFs are released by cells using the conventional secretory pathwa
Externí odkaz:
https://doaj.org/article/5369028b02574eedbb75af36e1e6b04b
Autor:
Martyna Sochacka, Radoslaw Karelus, Lukasz Opalinski, Daniel Krowarsch, Martyna Biadun, Jacek Otlewski, Malgorzata Zakrzewska
Publikováno v:
Cell Communication and Signaling, Vol 20, Iss 1, Pp 1-14 (2022)
Abstract Among the FGF proteins, the least characterized superfamily is the group of fibroblast growth factor homologous factors (FHFs). To date, the main role of FHFs has been primarily seen in the modulation of voltage-gated ion channels, but a ful
Externí odkaz:
https://doaj.org/article/a81e8c554fe84a4d83928deb13e1dbef
Autor:
Jakub Szymczyk, Martyna Sochacka, Patryk Chudy, Lukasz Opalinski, Jacek Otlewski, Malgorzata Zakrzewska
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Cancer drug resistance is a common, unpredictable phenomenon that develops in many types of tumors, resulting in the poor efficacy of current anticancer therapies. One of the most common, and yet the most complex causes of drug resistance is a mechan
Externí odkaz:
https://doaj.org/article/045db4a4281e4b349fe0209aea3a1f9a
Autor:
Aleksandra Gedaj, Dominika Zukowska, Natalia Porebska, Marta Pozniak, Mateusz Krzyscik, Aleksandra Czyrek, Daniel Krowarsch, Malgorzata Zakrzewska, Jacek Otlewski, Lukasz Opalinski
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/4263889e564240a8a62044afc630546c
Autor:
Marta Pozniak, Aleksandra Sokolowska‐Wedzina, Kamil Jastrzebski, Jakub Szymczyk, Natalia Porebska, Mateusz Adam Krzyscik, Malgorzata Zakrzewska, Marta Miaczynska, Jacek Otlewski, Lukasz Opalinski
Publikováno v:
Molecular Oncology, Vol 14, Iss 9, Pp 1998-2021 (2020)
Fibroblast growth factor receptor 1 (FGFR1) transmits signals through the plasma membrane regulating essential cellular processes like division, motility, metabolism, and death. Overexpression of FGFR1 is observed in numerous tumors and thus constitu
Externí odkaz:
https://doaj.org/article/41add822f32c4099b544103cf1062b2c
Autor:
Martyna Sochacka, Lukasz Opalinski, Jakub Szymczyk, Marta B. Zimoch, Aleksandra Czyrek, Daniel Krowarsch, Jacek Otlewski, Malgorzata Zakrzewska
Publikováno v:
Cell Communication and Signaling, Vol 18, Iss 1, Pp 1-11 (2020)
Abstract Fibroblast growth factors (FGFs) via their receptors (FGFRs) transduce signals from the extracellular space to the cell interior, modulating pivotal cellular processes such as cell proliferation, motility, metabolism and death. FGF superfami
Externí odkaz:
https://doaj.org/article/9e3057e0259c47fa9f2490faf4ec21a9
Autor:
Anna Szlachcic, Martyna Sochacka, Aleksandra Czyrek, Lukasz Opalinski, Daniel Krowarsch, Jacek Otlewski, Malgorzata Zakrzewska
Publikováno v:
Cells, Vol 8, Iss 8, p 899 (2019)
Fibroblast growth factor 1 (FGF1) has been shown to interact with integrin αvβ3 through a specific binding site, involving Arg35 residue. The FGF1 mutant (R35E) with impaired integrin binding was found to be defective in its proliferative response,
Externí odkaz:
https://doaj.org/article/0c367a45b8d1447bb3ca64eca4bdc6e9
Autor:
Chorążewska, Aleksandra, Regan, Darragh, Kalka, Marta, Ciura, Krzysztof, Porębska, Natalia, Łukasz Opaliński
Publikováno v:
In Protein Expression and Purification March 2025 227
Autor:
Aleksandra Gedaj, Dominika Zukowska, Natalia Porebska, Marta Pozniak, Mateusz Krzyscik, Aleksandra Czyrek, Daniel Krowarsch, Malgorzata Zakrzewska, Jacek Otlewski, Lukasz Opalinski
Publikováno v:
Cell Communication and Signaling. 21
Fibroblast growth factors (FGFs) and their receptors (FGFRs) constitute complex signaling hubs that are crucial for the development and homeostasis of the human body. Most of FGFs are released by cells using the conventional secretory pathway and are