Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Lukasz Jaskiewicz"'
Publikováno v:
Cells, Vol 12, Iss 3, p 468 (2023)
Aquaporins (AQPs) are selective, transmembrane proteins, which are primarily responsible for the transport of water and small molecules. They have been demonstrated to play a key role in the development and progression of cancer. Lung adenocarcinoma
Externí odkaz:
https://doaj.org/article/7cd5d83fe26640a597415f1dac624ad9
Autor:
Jean Hausser, Afzal Pasha Syed, Nathalie Selevsek, Erik van Nimwegen, Lukasz Jaskiewicz, Ruedi Aebersold, Mihaela Zavolan
Publikováno v:
Molecular Systems Biology, Vol 9, Iss 1, Pp 1-13 (2013)
Abstract MiRNAs are post‐transcriptional regulators that contribute to the establishment and maintenance of gene expression patterns. Although their biogenesis and decay appear to be under complex control, the implications of miRNA expression dynam
Externí odkaz:
https://doaj.org/article/0d7b2f3867684ba591fbf7dba2a03dea
Autor:
Valentina Vongrad, Jochen Imig, Pejman Mohammadi, Shivendra Kishore, Lukasz Jaskiewicz, Jonathan Hall, Huldrych F Günthard, Niko Beerenwinkel, Karin J Metzner
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0132127 (2015)
BACKGROUND:MiRNAs and other small noncoding RNAs (sncRNAs) are key players in post-transcriptional gene regulation. HIV-1 derived small noncoding RNAs (sncRNAs) have been described in HIV-1 infected cells, but their biological functions still remain
Externí odkaz:
https://doaj.org/article/07a157720b9d4c299ef111f384c70e2b
Autor:
Alessia Galgano, Michael Forrer, Lukasz Jaskiewicz, Alexander Kanitz, Mihaela Zavolan, André P Gerber
Publikováno v:
PLoS ONE, Vol 3, Iss 9, p e3164 (2008)
Genome-wide identification of mRNAs regulated by RNA-binding proteins is crucial to uncover post-transcriptional gene regulatory systems. The conserved PUF family RNA-binding proteins repress gene expression post-transcriptionally by binding to seque
Externí odkaz:
https://doaj.org/article/d2fc1fabeebf47e8b2fa89c7a7b3ef95
Autor:
Lukasz Jaskiewicz, Karolina Hejne, Blazej Szostak, Karolina Osowiecka, Mariusz T. Skowronski, Ewa Lepiarczyk, Anna Doboszynska, Marta Majewska, Pawel Kordowitzki, Agnieszka Skowronska
Publikováno v:
Journal of Clinical Medicine; Volume 11; Issue 19; Pages: 5954
Aquaporins (AQPs) are highly conserved channel proteins which are mainly responsible for the exchange of water and small molecules and have shown to play a pivotal role in the development and progression of cancer. Lung adenocarcinoma is the most com
Autor:
Patrycja Młotkowska, Mariusz T. Skowronski, Agnieszka Skowronska, Bartosz Kempisty, Chandra S. Pareek, Lukasz Jaskiewicz, Damian Tanski, Ewa Lepiarczyk
Publikováno v:
International Journal of Molecular Sciences
Volume 20
Issue 19
International Journal of Molecular Sciences, Vol 20, Iss 19, p 4914 (2019)
Volume 20
Issue 19
International Journal of Molecular Sciences, Vol 20, Iss 19, p 4914 (2019)
This study aimed to examine the effect of follicle-stimulating hormone (FSH), luteinizing hormone (LH), prolactin (PRL), and growth hormone (GH) on Aquaporin 5 (AQP5) expression in granulosa (Gc) and theca cells (Tc) from medium (MF) and large (LF) o
Autor:
David J. Lewis, Sandra Jullian, Hans-Jürgen Pfannkuche, Jeremy Parker, Philippe Close, Isabelle Lalande-Luesink, Lukasz Jaskiewicz
Publikováno v:
Pharmacoepidemiology and Drug Safety. 24:971-979
Purpose Marketing authorization holders (MAHs) are expected to provide high-quality periodic safety update reports (PSURs) on their pharmaceutical products to health authorities (HAs). We present a novel instrument aiming at improving quality of PSUR
Autor:
Ralf Zimmer, Mihaela Zavolan, Diana Lieber, Lars Dölken, Jürgen Haas, Lukasz Jaskiewicz, Florian Erhard, Georg Malterer
Publikováno v:
Erhard, F, Haas, J, Lieber, D, Malterer, G, Jaskiewicz, L, Zavolan, M, Doelken, L & Zimmer, R 2014, ' Widespread context dependency of microRNA-mediated regulation ', Genome Research, vol. 24, no. 6, pp. 906-919 . https://doi.org/10.1101/gr.166702.113
Gene expression is regulated in a context-dependent, cell-type-specific manner. Condition-specific transcription is dependent on the presence of transcription factors (TFs) that can activate or inhibit its target genes (global context). Additional fa
Publikováno v:
Medicina, Vol 60, Iss 3, p 392 (2024)
Macrophage activation syndrome is an uncommon yet dangerous and potentially fatal complication of many rheumatic diseases, inducing multiple organ failure, including, although rarely, acute heart failure. In the following paper, we present a case of
Externí odkaz:
https://doaj.org/article/5d03bd7c741d499389b79d1b84eede38
Publikováno v:
Genome Research. 19:2009-2020
How miRNAs recognize their target sites is a puzzle that many experimental and computational studies aimed to solve. Several features, such as perfect pairing of the miRNA seed, additional pairing in the 3′ region of the miRNA, relative position in