Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Lukasz Hajdo"'
Publikováno v:
Proceedings of the National Academy of Sciences. 113
Single-molecule experiments have been used with great success to explore the mechanochemical cycles of processive motor proteins such as kinesin-1, but it has proven difficult to apply these approaches to nonprocessive motors. Therefore, the mechanoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a01719d7013afc5578f0c7959666421c
https://doi.org/10.1073/pnas.1525313113
https://doi.org/10.1073/pnas.1525313113
Publikováno v:
Drug Development Research. 71:383-394
Purine and pyrimidine nucleoside analogs (NAs) are antimetabolites commonly used in cancer therapy. Administered as prodrugs, NAs permeate the mambrane using specialized transporters. Following phosphorylation, they interfere with multiple cellular p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::81093fac82b3a1235b287186219a1e3c
https://doi.org/10.1002/ddr.20390
https://doi.org/10.1002/ddr.20390
Autor:
Cordula Reuther, Andrzej A. Kasprzak, Stefan Diez, Lukasz Hajdo, Gero Fink, Krzysztof Skowronek
Publikováno v:
Nature Cell Biology. 11:717-723
During mitosis and meiosis, the bipolar spindle facilitates chromosome segregation through microtubule sliding as well as microtubule growth and shrinkage. Kinesin-14, one of the motors involved, causes spindle collapse in the absence of kinesin-5 (R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::863fae422e1574d3ba616c2fa2015e6c
https://doi.org/10.1038/ncb1877
https://doi.org/10.1038/ncb1877
Publikováno v:
Nano letters. 6(10)
We report on the generation of nanometer-wide, non-topographical patterns of proteins on planar surfaces. In particular, we used the regular lattice of reconstituted microtubules as template structures to specifically bind and transfer kinesin-1 and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20817b213279c31ed0fa2886945aac90
https://pubmed.ncbi.nlm.nih.gov/17034079
https://pubmed.ncbi.nlm.nih.gov/17034079
Publikováno v:
Archives of biochemistry and biophysics. 421(2)
Kinesins are molecular motors that produce mechanical work at the expense of ATP hydrolysis. Here, we studied Ncd (non-claret disjunctional), a (-)-end-directed member of this superfamily. To gain insight into the mechanism by which Ncd generates for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a0da2726cf2314209a33efe45af8580
https://pubmed.ncbi.nlm.nih.gov/14984201
https://pubmed.ncbi.nlm.nih.gov/14984201
Publikováno v:
Nano Letters; Oct2006, Vol. 6 Issue 10, p2177-2183, 7p