Guanosine Neuroprotection of Presynaptic Mitochondrial Calcium Homeostasis in a Mouse Study with Amyloid-β Oligomers.

Autor: da Silva JS; Graduate Program in Biological Sciences - Biochemistry. Department of Biochemistry, Institute of Basic Health Sciences, Federal University of Rio Grande do Sul - UFRGS, Porto Alegre, Brazil., Nonose Y; Graduate Program in Biological Sciences - Biochemistry. Department of Biochemistry, Institute of Basic Health Sciences, Federal University of Rio Grande do Sul - UFRGS, Porto Alegre, Brazil., Rohden F; Graduate Program in Biological Sciences - Biochemistry. Department of Biochemistry, Institute of Basic Health Sciences, Federal University of Rio Grande do Sul - UFRGS, Porto Alegre, Brazil., Lukasewicz Ferreira PC; Graduate Program in Biological Sciences - Biochemistry. Department of Biochemistry, Institute of Basic Health Sciences, Federal University of Rio Grande do Sul - UFRGS, Porto Alegre, Brazil., Fontella FU; Graduate Program in Biological Sciences - Biochemistry. Department of Biochemistry, Institute of Basic Health Sciences, Federal University of Rio Grande do Sul - UFRGS, Porto Alegre, Brazil., Rocha A; Graduate Program in Biological Sciences - Biochemistry. Department of Biochemistry, Institute of Basic Health Sciences, Federal University of Rio Grande do Sul - UFRGS, Porto Alegre, Brazil., Brochier AW; Graduate Program in Biological Sciences - Biochemistry. Department of Biochemistry, Institute of Basic Health Sciences, Federal University of Rio Grande do Sul - UFRGS, Porto Alegre, Brazil., Apel RV; Graduate Program in Biological Sciences - Biochemistry. Department of Biochemistry, Institute of Basic Health Sciences, Federal University of Rio Grande do Sul - UFRGS, Porto Alegre, Brazil., de Lima TM; Graduate Program in Biological Sciences - Biochemistry. Department of Biochemistry, Institute of Basic Health Sciences, Federal University of Rio Grande do Sul - UFRGS, Porto Alegre, Brazil., Seminotti B; Graduate Program in Biological Sciences - Biochemistry. Department of Biochemistry, Institute of Basic Health Sciences, Federal University of Rio Grande do Sul - UFRGS, Porto Alegre, Brazil., Amaral AU; Graduate Program in Biological Sciences - Biochemistry. Department of Biochemistry, Institute of Basic Health Sciences, Federal University of Rio Grande do Sul - UFRGS, Porto Alegre, Brazil.; Department of Biological Sciences, Integrated Regional University of High Uruguay and Missions - URI, Erechim, Brazil., Galina A; Laboratory of Bioenergetics and Mitochondrial Physiology. Graduate Program in Cellular Biophysics and Biochemistry. Institute of Medical Biochemistry Leopoldo de Meis, Health Sciences Centre, Federal University of Rio de Janeiro - UFRJ, Rio de Janeiro, Brazil., Souza DO; Graduate Program in Biological Sciences - Biochemistry. Department of Biochemistry, Institute of Basic Health Sciences, Federal University of Rio Grande do Sul - UFRGS, Porto Alegre, Brazil. diogo.bioq@gmail.com.

Publikováno v: Molecular neurobiology [Mol Neurobiol] 2020 Nov; Vol. 57 (11), pp. 4790-4809. Date of Electronic Publication: 2020 Aug 13.

Activated peripheral blood mononuclear cell mediators trigger astrocyte reactivity.

Autor: Bellaver B; Graduate Program in Biological Sciences: Biochemistry, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil., Rocha AS; Graduate Program in Biological Sciences: Biochemistry, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil., Souza DG; Graduate Program in Biological Sciences: Biochemistry, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil., Leffa DT; Graduate Program in Medicine: Medical Sciences, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil., De Bastiani MA; Graduate Program in Biological Sciences: Biochemistry, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil., Schu G; Graduate Program in Biological Sciences: Biochemistry, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil., Lukasewicz Ferreira PC; Graduate Program in Pharmaceutical Science, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil., Venturin GT; Preclinical Imaging Center, Brain Institute (BraIns) of Rio Grande do Sul, Porto Alegre, Brazil., Greggio S; Preclinical Imaging Center, Brain Institute (BraIns) of Rio Grande do Sul, Porto Alegre, Brazil., Ribeiro CT; Graduate Program in Biological Sciences: Biochemistry, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil., da Costa JC; Preclinical Imaging Center, Brain Institute (BraIns) of Rio Grande do Sul, Porto Alegre, Brazil., Moreira JCF; Graduate Program in Biological Sciences: Biochemistry, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil; Department of Biochemistry, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil., Gelain DP; Graduate Program in Biological Sciences: Biochemistry, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil; Department of Biochemistry, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil., Torres ILDS; Graduate Program in Medicine: Medical Sciences, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil; Graduate Program in Biological Sciences: Pharmacology and Therapeutics, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil; Departament of Pharmacology, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil., Klamt F; Graduate Program in Biological Sciences: Biochemistry, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil; Laboratory of Cellular Biochemistry, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil., Zimmer ER; Graduate Program in Biological Sciences: Biochemistry, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil; Graduate Program in Biological Sciences: Pharmacology and Therapeutics, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil; Departament of Pharmacology, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil. Electronic address: http://www.zimmer-lab.org.

Publikováno v: Brain, behavior, and immunity [Brain Behav Immun] 2019 Aug; Vol. 80, pp. 879-888. Date of Electronic Publication: 2019 Jun 05.