Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Lukas T. Goerttler"'
Autor:
Thomas F.E. Barth, Silke Brüderlein, Peter Möller, Adrienne M. Flanagan, Markus Schultheiss, Alexandra von Baer, Regine Mayer-Steinacker, Marko Kornmann, Michael Böhm, Kevin Mellert, André Lechel, Holger Barth, Ralf Marienfeld, Lukas T. Goerttler, Adrian von Witzleben
Overview ideogram of CGH data of all chordoma cell lines. Every cell line corresponds to one color. Lines on the left side are losses, and on the right side are gains of chromosomal material. Arrows mark the CDK6 region on 7q and p16 region on 9p.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22432424b3589aded01b88cbefae001b
https://doi.org/10.1158/0008-5472.22405980
https://doi.org/10.1158/0008-5472.22405980
Autor:
Thomas F.E. Barth, Silke Brüderlein, Peter Möller, Adrienne M. Flanagan, Markus Schultheiss, Alexandra von Baer, Regine Mayer-Steinacker, Marko Kornmann, Michael Böhm, Kevin Mellert, André Lechel, Holger Barth, Ralf Marienfeld, Lukas T. Goerttler, Adrian von Witzleben
Detailed CGH karyograms of the chordoma cell lines as shown in the ideogram in Supplementary Figure 1 (according to ISCN: International System for Human Cytogentic Nomenclature).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bfb5a546a6fe306ace804d42f52d913
https://doi.org/10.1158/0008-5472.22405947.v1
https://doi.org/10.1158/0008-5472.22405947.v1
Autor:
Thomas F.E. Barth, Silke Brüderlein, Peter Möller, Adrienne M. Flanagan, Markus Schultheiss, Alexandra von Baer, Regine Mayer-Steinacker, Marko Kornmann, Michael Böhm, Kevin Mellert, André Lechel, Holger Barth, Ralf Marienfeld, Lukas T. Goerttler, Adrian von Witzleben
Results of the single tandem repeats analysis of the cell lines U-CH1, U-CH2, UCH3, UCH6, UCH7, U-CH10, U-CH11 and UCH12. The results of the sex typing marker AMEL and the detected alleles for the markers D3S1358, D1S1656, D2S441, D10S1248, D13S317,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d69c2c151f2d7436e431e5661051d346
https://doi.org/10.1158/0008-5472.22405935
https://doi.org/10.1158/0008-5472.22405935
Autor:
Thomas F.E. Barth, Silke Brüderlein, Peter Möller, Adrienne M. Flanagan, Markus Schultheiss, Alexandra von Baer, Regine Mayer-Steinacker, Marko Kornmann, Michael Böhm, Kevin Mellert, André Lechel, Holger Barth, Ralf Marienfeld, Lukas T. Goerttler, Adrian von Witzleben
Expression data of mRNA as shown by box plot graphs for brachyury (A), collagen 2A1 (B) and CD24 (C).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d76d51bc136c951cf4eb24b0a813b34
https://doi.org/10.1158/0008-5472.22405968
https://doi.org/10.1158/0008-5472.22405968
Autor:
Thomas F.E. Barth, Silke Brüderlein, Peter Möller, Adrienne M. Flanagan, Markus Schultheiss, Alexandra von Baer, Regine Mayer-Steinacker, Marko Kornmann, Michael Böhm, Kevin Mellert, André Lechel, Holger Barth, Ralf Marienfeld, Lukas T. Goerttler, Adrian von Witzleben
Unsupervised cluster analysis of mRNA expression data of all chordoma cell lines. The T-gene (i.e., brachyury) is overexpressed (red). Cluster Analysis of chordoma cell lines with chondrocyte, liposarcoma and sarcoma expression data from GEO and own
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::001350286941634aa2d4c28074da49ef
https://doi.org/10.1158/0008-5472.22405965
https://doi.org/10.1158/0008-5472.22405965
Autor:
Thomas F.E. Barth, Silke Brüderlein, Peter Möller, Adrienne M. Flanagan, Markus Schultheiss, Alexandra von Baer, Regine Mayer-Steinacker, Marko Kornmann, Michael Böhm, Kevin Mellert, André Lechel, Holger Barth, Ralf Marienfeld, Lukas T. Goerttler, Adrian von Witzleben
Effect of Abemaciclib (LY2835219) on the growth of chordoma lines U-CH1, U-CH6, CAL51 (negative control), and MCF7 (positive control). Cells were grown in 96-well-plates were incubated for 3 days at 37{degree sign}C with increasing concentrations of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da51fa6256d47d79bab1ebc007066fa1
https://doi.org/10.1158/0008-5472.22405953.v1
https://doi.org/10.1158/0008-5472.22405953.v1
Autor:
Thomas F.E. Barth, Silke Brüderlein, Peter Möller, Adrienne M. Flanagan, Markus Schultheiss, Alexandra von Baer, Regine Mayer-Steinacker, Marko Kornmann, Michael Böhm, Kevin Mellert, André Lechel, Holger Barth, Ralf Marienfeld, Lukas T. Goerttler, Adrian von Witzleben
Western blot analyses of 8 chordoma cell lines showing expression of brachyury at 47 kDa.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::218778bf53706d7326e13063b4d28807
https://doi.org/10.1158/0008-5472.22405974
https://doi.org/10.1158/0008-5472.22405974
Autor:
Thomas F.E. Barth, Silke Brüderlein, Peter Möller, Adrienne M. Flanagan, Markus Schultheiss, Alexandra von Baer, Regine Mayer-Steinacker, Marko Kornmann, Michael Böhm, Kevin Mellert, André Lechel, Holger Barth, Ralf Marienfeld, Lukas T. Goerttler, Adrian von Witzleben
Clinical data of chordoma patients. Every sample was positive for brachyury. Asterisks (*) mark the parental chordomas of the established chordoma cell lines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e06f53ed9a11b78038228f0184130c3
https://doi.org/10.1158/0008-5472.22405941
https://doi.org/10.1158/0008-5472.22405941
Autor:
Thomas F.E. Barth, Silke Brüderlein, Peter Möller, Adrienne M. Flanagan, Markus Schultheiss, Alexandra von Baer, Regine Mayer-Steinacker, Marko Kornmann, Michael Böhm, Kevin Mellert, André Lechel, Holger Barth, Ralf Marienfeld, Lukas T. Goerttler, Adrian von Witzleben
Proliferation assay using Alamar Blue assay for U-CH2, 3, 6 and 10. Increasing concentrations of Palbociclib lead to an increase of growth inhibition of chordoma cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54b636dcb254f351092b0cb15063436b
https://doi.org/10.1158/0008-5472.22405959.v1
https://doi.org/10.1158/0008-5472.22405959.v1
Autor:
Thomas F.E. Barth, Silke Brüderlein, Peter Möller, Adrienne M. Flanagan, Markus Schultheiss, Alexandra von Baer, Regine Mayer-Steinacker, Marko Kornmann, Michael Böhm, Kevin Mellert, André Lechel, Holger Barth, Ralf Marienfeld, Lukas T. Goerttler, Adrian von Witzleben
Inversion microscopy views of the published chordoma cell lines U-CH1, U-CH2, U-CH 3, 6, 7, 10, 11, and 12. The cells showing the typical physaliphorous cytology; bars=100µm.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::751df4032216c14d0342921d14df243f
https://doi.org/10.1158/0008-5472.22405977
https://doi.org/10.1158/0008-5472.22405977