Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Lukas Schrangl"'
Advanced Quantification of Receptor–Ligand Interaction Lifetimes via Single-Molecule FRET Microscopy
Autor:
Lukas Schrangl, Vanessa Mühlgrabner, René Platzer, Florian Kellner, Josephine Wieland, Reinhard Obst, José L. Toca-Herrera, Johannes B. Huppa, Gerhard J. Schütz, Janett Göhring
Publikováno v:
Biomolecules, Vol 14, Iss 8, p 1001 (2024)
Receptor–ligand interactions at cell interfaces initiate signaling cascades essential for cellular communication and effector functions. Specifically, T cell receptor (TCR) interactions with pathogen-derived peptides presented by the major histocom
Externí odkaz:
https://doaj.org/article/f6adba3fa60549a596c4b8d1a3fc9875
Autor:
Janett Göhring, Florian Kellner, Lukas Schrangl, René Platzer, Enrico Klotzsch, Hannes Stockinger, Johannes B. Huppa, Gerhard J. Schütz
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Mechanical forces acting on ligand-engaged T-cell receptors (TCRs) have previously been implicated in T-cell antigen recognition, yet their sensitivity and specificity are still poorly defined. Here, authors report a FRET-based sensor that informs di
Externí odkaz:
https://doaj.org/article/9aaa195dbacc438b8940b42f235fb0e2
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Efficient scanning of tissue that T cells encounter during their migratory life is pivotal to protective adaptive immunity. In fact, T cells can detect even a single antigenic peptide/MHC complex (pMHC) among thousands of structurally similar yet non
Externí odkaz:
https://doaj.org/article/f1ba4d92a052403e9b4a4fc397e205ba
Autor:
Alexander W. A. F. Reismann, Lea Atanasova, Lukas Schrangl, Susanne Zeilinger, Gerhard J. Schütz
Publikováno v:
Molecules, Vol 23, Iss 12, p 3338 (2018)
Single molecule localization microscopy is currently revolutionizing the life sciences as it offers, for the first time, insights into the organization of biological samples below the classical diffraction limit of light microscopy. While there have
Externí odkaz:
https://doaj.org/article/38c6c6e5b35e44a29af90ceff176c9a9
Publikováno v:
Journal of Visualized Experiments.
Single-molecule Förster resonance energy transfer (smFRET) is a versatile technique reporting on distances in the sub-nanometer to nanometer range. It has been used in a wide range of biophysical and molecular biological experiments, including the m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::035daf853a5861b7565c62d345c78a16
https://doi.org/10.3791/63124-v
https://doi.org/10.3791/63124-v
Autor:
Caroline Kopittke, Joschka Hellmeier, Martin Fölser, Lukas Schrangl, Gerhard J. Schütz, Mario O. Brameshuber
Publikováno v:
Biophysical Journal. 121:84a-85a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f866eb65acb9cddf2da95b19790571b3
https://doi.org/10.1016/j.bpj.2021.11.2284
https://doi.org/10.1016/j.bpj.2021.11.2284
Autor:
Johannes B. Huppa, Lukas Schrangl, Florian Kellner, Enrico Klotzsch, Hannes Stockinger, Janett Göhring, René Platzer, Gerhard J. Schütz
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communications, 12 (1)
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communications, 12 (1)
Mechanical forces acting on ligand-engaged T-cell receptors (TCRs) have previously been implicated in T-cell antigen recognition, yet their magnitude, spread, and temporal behavior are still poorly defined. We here report a FRET-based sensor equipped
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee109d3e934c4d43c3f6fae41077449d
Autor:
Janett Goehring, René Platzer, Johannes B. Huppa, Gerhard J. Schütz, Lukas Schrangl, Hannes Stockinger, Florian Kellner
Publikováno v:
Biophysical Journal. 120:102a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4cb22fcad867478b0ab00a89340d32e3
https://doi.org/10.1016/j.bpj.2020.11.832
https://doi.org/10.1016/j.bpj.2020.11.832
Autor:
Lukas Schrangl, Wolfgang Driever, Philipp Wortmann, Ritwick Sawarkar, Chenyang Lan, Marina Veil, April Garcia Fernando, Gerhard J. Schuetz, Thorsten Hugel, Abhinaya Anandamurugan
Publikováno v:
Biophysical Journal. 120:114a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d08257281a9a3990c853f4441eb8a0fc
https://doi.org/10.1016/j.bpj.2020.11.2272
https://doi.org/10.1016/j.bpj.2020.11.2272
Autor:
Lea Atanasova, Gerhard J. Schütz, Susanne Zeilinger, Lukas Schrangl, Alexander W.A.F. Reismann
Publikováno v:
Molecules
Molecules, Vol 23, Iss 12, p 3338 (2018)
Volume 23
Issue 12
Molecules, Vol 23, Iss 12, p 3338 (2018)
Volume 23
Issue 12
Single molecule localization microscopy is currently revolutionizing the life sciences as it offers, for the first time, insights into the organization of biological samples below the classical diffraction limit of light microscopy. While there have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::583dc35d0898585b46da396a925a9567
https://pubmed.ncbi.nlm.nih.gov/30562966
https://pubmed.ncbi.nlm.nih.gov/30562966