Zobrazeno 1 - 10
of 2 066
pro vyhledávání: '"Lukas S"'
Autor:
Lukas S. Schaffer, Sophie Breunig, Jeremy M. Lawrence, Isabelle F. Foote, Andrew D. Grotzinger
Publikováno v:
Molecular Autism, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Background Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by atypical patterns of social functioning and repetitive/restricted behaviors. ASD commonly co-occurs with ADHD and, despite their clinical distinctiv
Externí odkaz:
https://doaj.org/article/ced400509eef4999839217da22b1ab66
Autor:
Robert Herold, Hayarpi Gevorgyan, Lukas S. Damerau, Ulrich Hartmann, Daniel Friemert, Rolf Ellegast, Christoph Schiefer, Kiros Karamanidis, Volker Harth, Claudia Terschüren
Publikováno v:
Sensors, Vol 24, Iss 20, p 6515 (2024)
The usage of smart glasses in goods logistics and order picking has mainly been studied through cross-sectional experimental studies. Our longitudinal field study investigated the effects of smart glasses on the eyesight of 43 employees at two German
Externí odkaz:
https://doaj.org/article/01ec23a0d32a40e9baa898a77fc84123
Autor:
David Flores-Solis, Irina P. Lushpinskaia, Anton A. Polyansky, Arya Changiarath, Marc Boehning, Milana Mirkovic, James Walshe, Lisa M. Pietrek, Patrick Cramer, Lukas S. Stelzl, Bojan Zagrovic, Markus Zweckstetter
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Eukaryotic gene regulation and pre-mRNA transcription depend on the carboxy-terminal domain (CTD) of RNA polymerase (Pol) II. Due to its highly repetitive, intrinsically disordered sequence, the CTD enables clustering and phase separation of
Externí odkaz:
https://doaj.org/article/d764f11023754998bb583c1d63ee30b3
Publikováno v:
Clinical and Translational Neuroscience, Vol 8, Iss 2, p 21 (2024)
The importance of sleep for healthy brain function is widely acknowledged. However, it remains unclear how the internal generation of dreams might facilitate cognitive processes. In this perspective, we review a computational approach inspired by art
Externí odkaz:
https://doaj.org/article/924cd8aae4544b298054952e9073b4ba
Publikováno v:
JHEP Reports, Vol 5, Iss 11, Pp 100882- (2023)
Summary: Patients with common variable immunodeficiency (CVID) frequently develop liver disease and associated complications, which represent an increasingly prevalent unmet medical need. The main hepatic manifestation of CVID is nodular regenerative
Externí odkaz:
https://doaj.org/article/a06cad66b1454b1ea7a577b33d4e4f11
Autor:
Steven Hiemstra, Mirjam Fehling-Kaschek, Isoude A. Kuijper, Luc J. M. Bischoff, Lukas S. Wijaya, Marcus Rosenblatt, Jeroen Esselink, Allard van Egmond, Jornt Mos, Joost B. Beltman, Jens Timmer, Bob van de Water, Daniel Kaschek
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Cells are exposed to oxidative stress and reactive metabolites every day. The Nrf2 signaling pathway responds to oxidative stress by upregulation of antioxidants like glutathione (GSH) to compensate the stress insult and re-establish homeost
Externí odkaz:
https://doaj.org/article/15080c2445a249f3aa5307f2274fe4e7
Autor:
Lukas S. Stelzl, Lisa M. Pietrek, Andrea Holla, Javier Oroz, Mateusz Sikora, Jürgen Köfinger, Benjamin Schuler, Markus Zweckstetter, Gerhard Hummer
Publikováno v:
JACS Au, Vol 2, Iss 3, Pp 673-686 (2022)
Externí odkaz:
https://doaj.org/article/1ab0d99f678148b7bfcf7450f680de6d
Publikováno v:
Laryngoscope Investigative Otolaryngology, Vol 6, Iss 5, Pp 1024-1030 (2021)
Abstract Background Autologous fat grafting (AFG) is evolving in both aesthetic and reconstructive applications, since the body of evidence for its use has expanded. The earliest controversies were evident in lipofilling for oncological breast recons
Externí odkaz:
https://doaj.org/article/797e3ce0457943bbbfa39c1c34234f58
Autor:
Justus F. Gräf, Ivan Mikicic, Xiaofei Ping, Claudia Scalera, Katharina Mayr, Lukas S. Stelzl, Petra Beli, Sebastian A. Wagner
Publikováno v:
iScience, Vol 25, Iss 9, Pp 104892- (2022)
Summary: PPM1D is a p53-regulated protein phosphatase that modulates the DNA damage response (DDR) and is frequently altered in cancer. Here, we employed chemical inhibition of PPM1D and quantitative mass spectrometry-based phosphoproteomics to ident
Externí odkaz:
https://doaj.org/article/912edcee7e754412a04cbb51e89a815a
Autor:
Muriel M Heldring, Lukas S Wijaya, Marije Niemeijer, Huan Yang, Talel Lakhal, Sylvia E Le Dévédec, Bob van de Water, Joost B Beltman
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 7, p e1010264 (2022)
Interindividual variability in DNA damage response (DDR) dynamics may evoke differences in susceptibility to cancer. However, pathway dynamics are often studied in cell lines as alternative to primary cells, disregarding variability. To compare DDR d
Externí odkaz:
https://doaj.org/article/bd05827ec19846e2a4c97f9f4699496c